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Rheumatology Plenary
Statin Myopathy: Self-Limited or Autoimmune Disease?

Date: 22 Sep 2023, Friday | Time: 1610 - 1655 | Track Type: Plenary Lecture | Venue: L2-S3 Combined, Academia

Speaker: Prof Lisa Christopher-Stine


This Plenary is proudly sponsored by:
Goh Cheng Liang Rheumatology ARISE Program Fund
 


In the last decade, there has been an increasing awareness that statin myopathy extends beyond that secondary to a direct toxic injury to the muscle that is usually self-limited. In addition to the more common self-limited statin myopathy, autoimmune statin myopathy (sometimes called statin associated necrotizing autoimmune myopathy (SANAM)) was described. Such patients have distinct clinical characteristics that can be distinguished from the more widely recognised self-limited toxic statin myopathy. With the applicability of anti-HMGCR auto anti-body testing, the diagnosis of autoimmune myopathy can be made from the combination of clinical recognition and laboratory testing. This presentation will shed insights on the distinction and clinical relevancy between these two entities with regards to long-term follow-up, safety of further lipid-lowering therapy and the appropriate therapeutic measures to be undertaken.


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