Name: Premature Neural Differentiation Regulated by FABP7 in Organoids Derived from Autism Individuals
Start: 2023-10-04T14:30:00.000+05:30
End: 2023-10-04T15:30:00.000+05:30
Location: Room 7C, Level 7, Duke-NUS

Overview Venue

Overview

You are invited to the upcoming seminar:
Presenter:
Prof Liu Yan
Professor in Neuroscience
Institute for Stem Cell and Neural Regeneration
Nanjing Medical University

Title: Premature neural differentiation regulated by FABP7 in organoids derived from autism individuals

Abstract:
The diverse clinical phenotypes of ASD have hampered the elucidation of pathological mechanisms. Based on iPSCs-derived cerebral organoids from ASD individuals, multiple cell lines and time series scRNA-seq combined with histomorphological analysis showed premature neural differentiation of neural stem cells and decreased expression of Fatty acid binding protein 7 (FABP7) in the ASD organoids. Meanwhile, upregulation of FABP7 rescued improper neural differentiation in the ASD organoids.

Seminar Details:
Date: 4 October 2023, Wednesday
Time: 2:30pm to 3:30pm

Venue:
Room 7C, Level 7, Duke-NUS

Host:
Asst Prof Alfred Sun
Principal Investigator
Neuroscience & Behavioural Disorders Programme
Duke-NUS

All are welcome. No registration is required.

Event Details

Date & Time

04 Oct 2023, 05:00 pm to 06:00 pm

Venue

Room 7C, Level 7, Duke-NUS

Audience

Community Partners,Healthcare Professionals

Language

English

Cost

Free

Venue

Room 7C, Level 7, Duke-NUS

Current Session

04 Oct 2023

Seminars Premature Neural Differentiation Regulated by FABP7 in Organoids Derived from Autism Individuals

Free 05:00 pm to 06:00 pm