Professor Ooi received his medical training at the University of Nottingham Medical School and his Ph.D. from the National University of Singapore in 1998. He was awarded a Fellowship from the Royal College of Pathologists, UK in 2013.
His research on dengue pathogenesis and immunity interfaces several different disciplines, namely clinical epidemiology, virology and immunology. His laboratory is keen to learn how antibodies either protect against or enhance dengue virus infection and what viral factors influence epidemic dengue activity.
Dr Jenny Low is a senior consultant with the Department of Infectious Diseases, Singapore General Hospital. Apart from patient consultations, her research addresses translational therapeutics and vaccinology for acute viral diseases with a focus on first-in-human and proof-of-concept clinical trials.
Eugenia OngPhD, Principal Research Scientist
Eugenia completed her PhD training in Integrated Biology and Medicine at Duke-NUS Medical School under the supervision of Prof. Eng Eong Ooi. Her PhD thesis focused on investigating Fc-gamma receptor signaling during antibody-enhanced dengue virus infection. She is interested in developing molecular tools that can provide an accurate assessment of safety and efficacy for evaluating vaccines and therapeutics for infectious diseases during early phase clinical trials. Other Affiliations:Principal Research Scientist, Programme in Emerging Infectious Diseases, Duke-NUS Medical School
Research interests: Antibody-dependent enhancement; Host-pathogen interactions; Pre-clinical development and adaptive trial design for therapeutics and vaccines
Contact: +65 6576 7090Email: eugenia.ong@duke-nus.edu.sg
Ayesa SyeninaPhD, Research Fellow
Ayesa completed her PhD training in Public Health at the Saw Swee Hock School of Public Health under the supervision of Prof. Eng Eong Ooi. Her PhD thesis focused on investigating the molecular determinants of dengue virus epidemiological fitness. She is interested in developing molecular tools to assess the outcome of early phase clinical trials of vaccines and therapeutics for infectious diseases.
Other Affiliations: Research Fellow, Programme in Emerging Infectious Diseases, Duke-NUS Medical School
Research interests: Host-pathogen interactions;Molecular determinants of viral epidemiological fitness; Pre-clinical and clinical development of therapeutics and vaccines.
Contact: +65 6576 7090Email: ayesa.syenina@duke-nus.edu.sg
Christine Tham PhD, Research Fellow Christine was an A*STAR scholar and obtained her PhD from the NUS Graduate School for Integrative Sciences and Technology, where she investigated the immunomodulatory role of viral hepatitis and its implications in immunotherapy. She is currently evaluating T cell responses in early phase human clinical trials involving vaccines and therapeutics. Other Affiliations: Research Fellow, Programme in Emerging Infectious Diseases, DUKE-NUS Medical School Research interests: Infectious diseases; Immuno-pathogenesis and clearance of viral infections; Clinical development of therapeutics Contact: +65 6576 7090Email: christinetham@duke-nus.edu.sg
Ngoh An Qi
PhD, Research Fellow
An Qi completed her PhD training in Integrated Biology and Medicine at Duke-NUS Medical School under the supervision of Prof. Subhash Vasudevan. Her PhD research centred on elucidating the native structure of the secreted non-structural protein 1 (sNS1) during DENV infection, where she developed and optimised protocols for sNS1 purification. She is interested in developing new and targeted assays that would better inform the clinical efficacy of vaccines and therapeutics.
Research interests:Infectious diseases;Assay Development;Clinical development of vaccines and therapeutics
Contact: +65 6576 7090Email: anqi.ngoh@duke-nus.edu.sg
Yan Shan LeongBSc, Senior Research AssistantYan Shan completed her BSc in Biomedical Science at the University of Bradford with specialisation in Medical Cell Biology. Subsequently, she joined Duke-NUS Medical School and the ViREMiCS team, where she is involved in virology and serology projects.
Research interests:Serology;Antibody responses to vaccination and natural infections;Pre-clinical and clinical vaccine development
Yee Jia Xin BBMED, Senior Research Assistant
Jia Xin received her Bachelor in Biomedicine from The University of Melbourne. She worked in Duke-NUS Medical School and subsequently joined ViREMiCS. She is interested in the development of vaccines and therapeutics, assessing the efficacy and optimising the clinical translation process. Research interests:Host-pathogen interaction;Pre-clinical and clinical development of vaccines and therapeutics Contact: +65 6576 7090Email: jiaxin.yee@duke-nus.edu.sg Valerie Chew MSc, Senior Research AssistantValerie completed her BSc and subsequently MSc in Infectious Diseases at the University of Western Australia. She then joined Duke-NUS Medical School and the ViREMiCS team, where she is involved in virology and serology projects.
Research interests:Flavivirus host-pathogen interaction;Pre-clinical and clinical vaccine development Contact: +65 6576 7090Email: valchew@duke-nus.edu.sg
Noor Zayanah HamisMScR, Senior Research AssistantZayanah completed her Master’s by Research in Cellular and Molecular Medicine at the University of Bristol under the supervision of Assoc Prof Dr Laura Rivino, where she studied responding T cells in acute dengue infection.
Research interests:Immunology of viral infections;Pre-clinical and clinical vaccine development of vaccines and therapeutics Contact: +65 6576 7090Email: noorzayanah@duke-nus.edu.sg
Nur Saffiah Zakaria BSc, Assistant Manager Saffiah completed her BSc in Accounting and Finance (Hons) at the University of London; LSE (SIM). She then joined Duke-NUS Medical School and the ViREMiCS team, where she is involved in managing the business administrative and finance related matters. Contact: +65 6576 7090Email: nur.saffiah@duke-nus.edu.sg
