Bioinformatics

The PRISM bioinformatics team has extensive experience in analyzing large-scale genomics datasets.

1) WGS analysis

• Germline variant calling (GATK) and annotation.
• Germline joint genotyping (GATK)
• Somatic variant calling (Strelka2) and annotation.
• Mutation signature analysis (deconstructSig).
• Copy-number variation (CNVnator) analysis
• Structural variation (Manta) analysis.

2) WES/Targeted analysis

• Germline variant calling (GATK) and annotation.
• Germline joint genotyping (GATK)
• Somatic variant calling (Strelka2) and annotation.

3) RNA-seq analysis

•   Gene/Transcript quantification and differential expression analysis

Bioinformatics Services Enquiry
We have a wide experience working with most -omics data types. Email prism@singhealth.com.sg and we will see how we can help you.

Other forms:
PRISM Data deposition policy -  SHS-RSH-OOR-CWP-204 PRISM Data Deposition Policy (Final).pdf