News

01 Feb 2024 - CIRB Updates

- Upcoming Trainings on ECOS

Click here.

15 Sep 2023 - CIRB Updates

The updates include:
- Revised CIRB Review Fee for Industry Sponsored Studies
- Management of IRB Study Documents in iSHaRe
- IRB Renewal and Extension of Validity Period
- Minimum Training Requirements

Click here for more details.

01 Mar 2023 - CIRB Updates

The updates include:
- Informed Consent Document (ICD) Template Update
- Revised Guidance on Requirements For Informed Consent Documents

Click here for more details.

30 Aug 2022 - CIRB Updates

The updates include:
- Assent Requirements and Template Update
- Informed Consent Document (ICD) Template Update
- Revised Guidance on Requirements For Informed Consent Documents
- New Consent Elements Checklist for Clinical Trials
- CIRB Application/ Amendment Form Update
- Change of CIRB Hotline Number

Click here for more details.

7 Apr 2022 - iSHaRe Internet Access
We regret to inform you that internet access to iSHaRe will not be available indefinitely.  iSHaRe is available for access via intranet and HVPN for SingHealth, NHG and NUHS users (Public Healthcare Institutions (PHI) users) only. Click here for more details. We apologize for any inconvenience caused.

26 NOV 2021 - CIRB Researcher Handbook

Have a research proposal in mind, but not sure where to begin? The handbook serves as a “one-stop center” to provide you with all the necessary information that guides you through the entire process till approval.

Click here to download a copy.

JUL 2021 - Human Subject Research Start-Up Course

The Human Subject Research Start-Up course is intended for Investigators, Researchers and any individual intending to conduct or be involved in Clinical Research involving human subjects. It will equip learners with essential information and key elements to plan start-up, carry out pre-study activities and initiate a Human Subject Research successfully. After completing the course, learners will be able to download a certificate of completion. The self-registration course can be accessed from the SingHealth eLearning portal by clicking here.

 
This course is optional but strongly encouraged for all researchers involved in a Human Subject Research.

  

19 MAR 2021: Update on iSHaRe

iSHaRe is currently available for access via intranet for SingHealth, NHG and NUHS users (Public Healthcare Institutions (PHI) users) only. The internet access remains unavailable. Please contact your collaborator or study team member from PHIs for assistance.

The registration of new iSHaRe account is currently not available for non-PHI users. For non-PHI users who need to be added to an IRB application or IRB approved studies, please download this "Changes to External Study Team members Form" and attach it under "Other Attachments" section of the CIRB Application/Amendment Form. Once the iSHaRe account is accessible, study team member (non-PHI user) should be added back to Section B2 through amendment. Please review the Study Team Members definition on CIRB FAQs page before submitting the form.

For Industry sponsored studies, sponsors are advised to work with the principal investigators’ institutions on the submissions of CIRB forms, checking of study status (e.g. Expiry Date) and retrieval of CIRB approved documents and decision letters.

15 FEB 2021: Revised CIRB Review Fees and Renewal Fee for Industry Sponsored Studies

With effect from 1 April 2021, CIRB review fee will be revised. In addition, renewal fee will be applied to Study Renewal Report Form and Study Reactivation Report Form received from 1 April 2021 onwards. Click here for more details.

15 SEP 2020 : CIRB Updates

The updates include:
- Reporting Timeline for Protocol Deviation and Non-compliance
- Removal of requirement to submit translated documents
- Revised Participant Information Sheet and Consent Form Template
- Additional/Extra Human Tissue Collection

Click here for more details.

27 MAY 2020 : HBRA Updates

SingHealth's Office of Research Integrity and Compliance (ORIC) has released guidance documents on de-identification and obtaining remote consent. Click on the links to find out more.

19 MAY 2020 : CIRB Updates

The updates include:
- Study Closure for Exemption Study
- Assessment of the Suitability of the Research Site by Department Representative/HOD and Institution Representative
- Revamped Participant Information Sheet and Consent Form Template
- iSHaRe Enhancement – Form Changes
- Updated Reporting Requirement and Timeline for Serious Adverse Events (SAE)
- Study Expiry Reminder Notifications
- Removal of Version Date and Version Number from Attachment Upload Component on iSHaRe

Click here for details.

28 APR 2020 : Submissions and notifications during COVID-19 Situation

Additional questions and clarifications have been added to the CIRB Updates released on 7 April 2020.

Click here for details.

7 APR 2020 : Submissions and notifications during COVID-19 Situation

The CIRB Updates provide important clarification on CIRB’s requirements on the following during COVID-19 situation:
- Changes to the research protocol that require CIRB’s review and approval prior to implementation.
- The reporting of Protocol Deviation/Non-compliance and Local Serious Adverse Event.

Click here for details.

24 MAR 2020 : Duke-NUS & SingHealth Collaborative Research Ethics Review

- NUS has appointed SingHealth Centralised Institutional Review Board (CIRB) for ethics review on collaborative research with SingHealth Institution(s) where Duke-NUS is involved.
- With effect from 1 April 2020, new collaborative studies that involve Duke-NUS and SingHealth Institutions can be submitted to CIRB. The lead PI can be from Duke-NUS or SingHealth Institution.
- The details can be found in the FAQ: Duke-NUS & SingHealth Collaborative Research Ethics Review document. Researchers should follow the guidance provided.

13 FEB 2020 : Reminder to complete Human Biomedical Research Act (HBRA) eLearning

Researchers are reminded to self-register and complete the HBRA Essentials eLearning course on the SingHealth eLearning catalogue here by 1 April 2020.

An updated section (mandatory for HBR studies and Tissue Banking) has been added to the course. Researchers working with HBR and Tissues from 1 November 2019 are to complete this section.