Koh, Tse Hsien

​ ​ ​	Title		​:   Clinical Professor
	​Address		​:   Department of Microbiology, Division of Pathology,     Singapore General Hospital Academia,     Diagnostics Tower, Level 7     20 College Road, Singapore 169856
	​Email		​:   koh.tse.hsien@singhealth.com.sg
	​Current Position		:   Senior Consultant and Head, Department of Microbiology,     Singapore General Hospital     Clinical Senior Lecturer, Yong Loo Lin School of Medicine,     National University of Singapore     Clinical Professor, Duke-NUS Medical                     School

Research interest:

Characterization and molecular epidemiology of antibiotic resistant bacteria. Community Klebsiella pneumoniae infections. Food, environmental and animal sources of bacteria that impact human health. Zoonotic bacterial infections.

Selected Publications:

1. Koh TH, Cao DY, Chan KS, Wijaya L, Low SB, Lam MS, Ooi EE, Hsu LY. bla(OXA-181)-positive Klebsiella pneumoniae, Singapore. Emerg Infect Dis. 2012 Sep;18(9):1524-5


2. Koh TH, Khoo CT, Wijaya L, Leong HN, Lo YL, Lim LC, Koh TY. Global spread of New Delhi metallo-β-lactamase 1. Lancet Infect Dis. 2010 Dec;10(12):828


3. Koh TH, Sng LH, Yuen SM, Thomas CK, Tan PL, Tan SH, Wong NS. Streptococcal cellulitis following preparation of fresh raw seafood. Zoonoses Public Health. 2009 May;56(4):206-8


4. Koh TH, Low BS, Leo N, Hsu LY, Lin RT, Krishnan P, Chan D, Nadarajah M, Toh SL, Ong KH. Molecular epidemiology of vancomycin-resistant enterococci in Singapore. Pathology. 2009;41(7):676-80


5. Koh TH, Yamaguchi K, Ishii Y. Characterisation of the metallo-beta-lactamase VIM-6 and its genetic support. Int J Antimicrob Agents. 2008 Nov;32(5):446-9


6. Sergio DM, Koh TH, Hsu LY, Ogden BE, Goh AL, Chow PK. Investigation of meticillin-resistant Staphylococcus aureus in pigs used for research. J Med Microbiol. 2007 Aug;56(Pt 8):1107-9


7. Koh TH, Sng LH, Wang GC, Hsu LY, Zhao Y. IMP-4 and OXA beta-lactamases in Acinetobacter baumannii from Singapore. J Antimicrob Chemother. 2007 Apr;59(4):627-32


8. Koh TH, Wang GC, Sng LH. Clonal spread of IMP-1-producing Pseudomonas aeruginosa in two hospitals in Singapore. J Clin Microbiol. 2004 Nov;42(11):5378-80


9. Koh TH, Wang GC, Sng LH. IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore. Antimicrob Agents Chemother. 2004 Jun;48(6):2334-6


10. Koh TH, Babini GS, Woodford N, Sng LH, Hall LM, Livermore DM. Carbapenem-hydrolysing IMP-1 beta-lactamase in Klebsiella pneumoniae from Singapore. Lancet. 1999 Jun 19;353(9170):2162