Pazopanib

• Nausea, vomiting, poor appetite
• Diarrhea
• Abdominal pain
• Tiredness and lack of energy
• Discoloration of skin and hair
• Bleeding gum
• High blood pressure
  Your blood pressure should be monitored closely. Discuss a proper follow-up plan with your doctor.
• Increased blood sugar level
  Maintain a healthy low sugar diet and have routine blood sugar checks.

Inform your doctor if any of the following occurs:

• Allergic reactions – rashes, facial swelling, breathing difficulty
• Rapid heartbeat or chest pain
• Sudden onset of cough, chest pain or shortness of breath
• Yellowing of the eyes or skin and severe abdominal pain
• Signs of infection – fever or chills, sore throat, pain or difficulty in urinating
• Prolonged gum bleeding or bleeding on other parts of the body
• Unusual weakness, tiredness or light-headedness
• Severe diarrhea

• Inform your doctor or pharmacist if you :
• Have any other medical conditions e.g. heart problems, high blood pressure, adrenal insufficiency
• Plan to start any new medicines or supplements.
• Effective birth control is recommended for both men and women during and for at least 2 weeks after treatment with Pazopanib. Inform your doctor if you plan to get or suspect that you are pregnant.
• Do not breastfeed. Inform your doctor if you intend to breastfeed while taking Pazopanib.
• Avoid going to crowded places or being too near sick people to minimize your risk of infection.

• Grapefruit and its juice.
• Medicines that reduce gastric acid, unless otherwise instructed by your doctor.