The Research Office of Pathology ACP provides administrative support to allow our researchers to focus on research activities with the ultimate aim of improving patient care. Some of the research activities in Pathology ACP are as follows:
The Pathology ACP Pitch-for-Funds Grant aims to promote laboratory-based research within Pathology ACP especially among junior doctors (residents/ trainees) and junior scientific/ technical staff.
The grant award will allow them to acquire experience in applying for grants, study design, project work, writing papers and presenting their data at an early stage of their career. It may also be used to jump start laboratory studies providing pilot data leading on to external and national grant funding.
We congratulate the following successful awardees and wish them every success in their research endeavours! We would also like to thank their mentors for their invaluable support and guidance!
Project Title:
Harmonisation study for 4 PD-L1 clones in triple negative breast cancer
Project Duration:1 Aug 2019 – 31 Jan 2021
Mentor(s):Prof Tan Puay HoonSenior Consultant & Chairman, SGH Div of Pathology
The utility of next-generation sequencing in diagnosis of histopathologically overlapped inflammatory myofibroblastic tumour and IgG4-related disease
Project Duration: 1 Aug 2019 – 31 Jan 2021
Mentor(s):Dr Angela TakanoSenior Consultant, SGH Dept of Anatomical Pathology
A/Prof Kenneth ChangSenior Consultant & Head, KKH Dept of Pathology and Laboratory Medicine
Ms Fiona LiawSenior Medical Laboratory Scientist (Clinical), SGH Dept of Molecular Pathology
1 Oct 2018 – 31 Mar 2020
Mentor(s):A/Prof Chuah Thuan Heng CharlesSenior Consultant, SGH Dept of HaematologyDirector, SGH Clinical Translational Research
A/Prof Tien Sim LengSenior Consultant, SGH Dept of Haematology
A/Prof Alvin LimAssistant Director, SGH Dept of Molecular Pathology
Dr Chow Chun Yuen Resident, SGH Dept of Anatomical Pathology
The utility of ERG and PTEN in diagnosing acinar adenocarcinoma of the prostate in core biopsy specimens and their value in predicting outcome in Singaporean men
Project Duration: 1 Oct 2018 – 31 Mar 2020
Dr Aye Aye ThikeSenior Medical Laboratory Scientist (Research), SGH Dept of Anatomical Pathology
Role of intra-tumoural cholesterol metabolism in breast cancer arising in young women
Project Title: Role of Next Generation Sequencing in Detection of Malignancy in Pancreatobiliary Brushings Specimen
Mentor(s):Dr Sangeeta MantooSenior Consultant, SGH Dept of Anatomical Pathology
Project Title: Metabolic changes in host cells during influenza virus infections
Project Duration:1 Oct 2017 – 31 Mar 2019
Mentor(s):Dr Chan Kwai PengSenior Consultant, SGH Dept of Microbiology
Project Title:
Multiplex immunofluorescence approach to study tumour-infiltrating lymphocytes in Triple-Negative Breast Cancer
Project Duration: 1 Oct 2017 – 31 Mar 2019
Mentor(s):Dr Jabed IqbalSenior Consultant, SGH Dept of Anatomical Pathology
Study of Janus Kinase 2 (JAK2) genomic alterations and potential role as biomarker in Triple Negative Breast Cancer
Dr Joe YeongSenior Research Fellow, SIgN, A*STAR
Project Title: A study on dengue virus susceptibility to Itraconazole
Dr Puong Kim YoongSenior Medical Laboratory Scientist (Clinical), SGH Dept of Molecular Pathology
Multiplex immunofluorescence approach to study tumour infiltrating lymphocytes: A breast cancer paradigm
Project Duration:1 Jan 2016 – 30 Jun 2017
Mentor(s):Dr Syed Salahuddin AhmedSenior Consultant, SGH Dept of Anatomical Pathology
Prof Tan Puay HoonSenior Consultant & Chairman, SGH Div of Pathology
Molecular profiling of Multiple Myeloma (MM) using Cytogenomic Microarray Analysis (CMA) with enriched plasma cell (PCs) populations
Project Duration: 1 Oct 2015 – 30 Sep 2017
Mentor(s):A/Prof Tony LimSenior Consultant & Head, SGH Dept of Anatomical Pathology
Dr Sathish Kumar GopalakrishnanConsultant, SGH Dept of Haematology
Using next generation sequencing (NGS) for the detection of genetic alterations on FFPE and its application on detection of common mutations in patients with dual primary malignancies.
Project Duration:1 Oct 2015 – 30 Sep 2017
Mentor(s):Dr Ronald GohConsultant, SGH Dept of Anatomical Pathology
A/Prof Tony LimSenior Consultant & Head, SGH Dept of Anatomical Pathology
Validating a suitable immunocytochemical protocol for the detection of circulating tumour cells
Dr Angela TakanoSenior Consultant, SGH Dept of Anatomical Pathology
Role of the reverse Warburg effect in tumorigenesis in Cervical Intra-epithelial Neoplasia
Project Duration:
1 Jul 2014 – 30 Sep 2016
Mentor(s):Dr Sangeeta MantooConsultant, SGH Dept of Anatomical Pathology
Dr Sophie BellangerIMB, A*STAR
Pilot study to investigate the accuracy of p16/Ki-67 immunocytochemical dual stain in detecting Cervical Intraepithelial Neoplasia (CIN) when applied to Papanicolou (Pap) cervical smears with atypical squamous cytology
1 Jul 2014 – 31 Mar 2016
Project Title: First survey of antibiotic susceptibility of anaerobic bacteria in a large tertiary hospital in Singapore
Project Duration:1 Jul 2014 – 31 Dec 2015
Mentor(s):Dr Tan Ai LingSenior Consultant, SGH Dept of Microbiology