Autoimmune Neurology

Neuroscience Symposium
Autoimmune Neurology

Date: 20 Sep 2025, Saturday | Time: 1355 - 1525 | Track Type: Symposium | Venue: L1-S1, Level 1, Academia

Neuroimmunology is a rapidly emerging field in neurology. There is now increasing recognition that many CNS diseases are primarily immune-mediated, some of which the antigenic targets have been identified. These CNS autoimmune diseases can present with diverse clinical symptoms and management requires an integrative and multi-disciplinary approach spanning various specialties such as neurology, neuroradiology, ophthalmology, psychiatry, intensive medicine, and rehabilitation medicine. Although their underlying pathogenesis are yet to be fully elucidated given the complexity of immune mechanisms, it is observed that generic immunomodulation and immunosuppression allow for these diseases to be treated, with varying success. There is currently huge interest in developing clinical biomarkers for diagnosis, monitoring of disease activity and assessing therapeutic response, as well as to gain a deeper mechanistic understanding into their pathophysiologies to allow for the development of targeted therapies.

In this symposium, subspecialty experts will highlight these CNS autoimmune diseases; specifically Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorder (NMOSD), Myelin Oligodendrocyte Glycoprotein antibody associated disease (MOGAD), Autoimmune Encephalitis, and Paediatric CNS Autoimmune diseases. They will detail the clinical phenotypes, diagnosis, immunopathophysiologies, and management of these diseases. Case presentations and advances in evidence-based clinical practice will be discussed to enhance audience learning. The speakers will also provide an update on the latest state-of-the-art basic and clinical research for these diseases. This session will be of relevance to neurologists, neuroradiologists, ophthalmologists, psychiatrists, psychologists, pain physicians, infectious disease specialists, intensivists, and rehabilitation specialists.

TOPIC 1:
Multiple Sclerosis: New insights and Treatment Strategies
Speaker: Dr Yeo Tianrong

TOPIC 2:
NMOSD and MOGAD: Antibodies Gone Rogue
Speaker: Assoc Prof Kevin Tan

TOPIC 3:
Autoimmune Encephalitis: The Borderlands of Neurology and Psychiatry
Speaker: Dr Amy Kwek

TOPIC 4:
Paediatric CNS Autoimmune Diseases
Speaker: Adj Asst Prof Simon Ling