Publications

“Cluster analysis and visualisation of electronic health records data to identify undiagnosed patients with rare genetic diseases” Scientific Reports 2024 March 

Daniel Moynihan, Sean Monaco, Teck Wah Ting, Kaavya Narasimhalu, Jenny Hsieh, Sylvia Kam, Jiin Ying Lim, Weng Khong Lim, Sonia Davila, Yasmin Bylstra, Iswaree Devi Balakrishnan, Mark Heng, Elian Chia, Khung Keong Yeo, Bee Keow Goh, Ritu Gupta, Tele Tan, Gareth Baynam, Saumya Shekhar Jamuar

“Loss-of-function SMPD1 gene variant in Progressive Supranuclear Palsy-Richardson Syndrome patients of Chinese ancestry” Journal of Movement Disorders 2024 January 

Shen-Yang Lim, Ai Huey Tan, Jia Nee Foo, Yi Jayne Tan, Elaine GY Chew, Azlina Ahmad Annuar, Alfand Marl Dy Closas, Azalea Pajo, Jia Lun Lim, Yi Wen Tay, Anis Nadhirah, Jia Wei Hor, Tzi Shin Toh, Lei Cheng Lit, Jannah Zulkefli, Su Juen Ngim, Weng Khong Lim, Huw R Morris, Eng-King Tan, Adeline SL Ng

“Identification of constrained sequence elements across 239 primate genomes” Nature 2024 January 

Lukas FK Kuderna, Jacob C Ulirsch, Sabrina Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J Cox, Hong Gao, Arvind Kumar, Francois Aguet, Matthew J Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria NF da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin MD Beck, Ioannis Karakikes, Kevin C Wang, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad-Toh, Jeffrey Rogers, Tomas Marques Bonet, Kyle Kai-How Farh

“A novel intronic variant in ROBO3 associated with horizontal gaze palsy with progressive scoliosis: case report and literature review” Journal of American Association for Pediatric Ophthalmology and Strabismus 2023 December 

Bryan Sim, Janice Wan Zhen Ng, Donald Yuhui Sim, Jeannette Goh, Sylvia Kam, Jing Xian Teo, Wan Wan Lim, Jane Lieviant, Weng Khong Lim, Su Ann Lim, Phua Hwee Tang, Simon Ling, Stacy Wei Ling Ng, Xavier Roca, Saumya Shekhar Jamuar

“NOTCH2NLC trinucleotide interruptions are associated with cognitive impairment in neuronal intranuclear inclusion disease (NIID)” Alzhermer’s & Dementia 2023 December 

Yi Jayne Tan, Zheyu Xu, Zhi‐Yong Chen, Weng Khong Lim, Simon Kang Seng Ting, Wai Yung Yu, Qian Hui Cheng, Jia Nee Foo, Eng‐King Tan, Tchoyoson CC Lim, Adeline Su Lyn Ng

“A Catalogue of Structural Variation across Ancestrally Diverse Asian Genomes” 2023 October

Nicolas Bertin, Joanna Tan, Zhihui Li, Mar Gonzalez-Porta, Ramesh Rajaby, Rodrigo Jimenez, Weng Khong Lim, Ye An Tan, Renyi Teo, Maxime Hebrard, Jack Ling Ow, Shimin Ang, Justin Jeyakani, Yap Seng Chong, Tock Han Lim, Liuh Ling Goh, Yih-Chung Tham, Khai Pang Leong, Calvin Chin, Sonia Davila, Ching-Yu Cheng, John Chambers, E Shyong Tai, Jianjun Liu, Xueling Sim, Wing-Kin Sung, Shyam Prabhakar, Patrick Tan, Jin-Fang Chai, Jimmy Lee, Eng Sing Lee, Joanne Ngeow, Paul Elliott, Elio Riboli, Hong Kiat Ng, Theresia Mina, Darwin Tay, Nilanjana Sadhu, Pritesh Rajesh Jain, Dorrain Low, Xiaoyan Wang, Khung Keong Yeo, Stuart Alexander Cook, Chee Jian Pua, Chengxi Yang, Tien Wong, Charumathi Sabanayagam, Lavanya Raghavan, Tin Aung, Miao Ling Chee, Miao Chee, Hengtong Li, Rob van Dam, Yik-Ying Teo, Chia Wei Lim, Pi Kuang Tsai, Wen Jie Chew, Wey Ching Sim, Li-xian Grace Toh, Johan Eriksson, Peter Gluckman, Yung Seng Lee, Fabian Yap, Kok Hian Tan

“Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes” Nature Communications 2023 September 

Qiao Fan, Hengtong Li, Xiaomeng Wang, Yih-Chung Tham, Kelvin Yi Chong Teo, Masayuki Yasuda, Weng Khong Lim, Yuet Ping Kwan, Jing Xian Teo, Ching-Jou Chen, Li Jia Chen, Jeeyun Ahn, Sonia Davila, Masahiro Miyake, Patrick Tan, Kyu Hyung Park, Chi Pui Pang, Chiea Chuan Khor, Tien Yin Wong, Yasuo Yanagi, Chui Ming Gemmy Cheung, Ching-Yu Cheng

“ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk” Clinical Cancer Research 2023 August 

Lenka Stolarova, Petra Kleiblova, Petra Zemankova, Barbora Stastna, Marketa Janatova, Jana Soukupova, Maria Isabel Achatz, Christine Ambrosone, Paraskevi Apostolou, Banu K Arun, Paul Auer, Mollie Barnard, Birgitte Bertelsen, Marinus J Blok, Nicholas Boddicker, Joan Brunet, Elizabeth S Burnside, Mariarosaria Calvello, Ian Campbell, Sock Hoai Chan, Fei Chen, Jian Bang Chiang, Anna Coppa, Laura Cortesi, Ana Crujeiras-González, Kim De Leeneer, Robin De Putter, Allison DePersia, Lisa Devereux, Susan Domchek, Anna Efremidis, Christoph Engel, Corinna Ernst, D Gareth R Evans, Lidia Feliubadaló, Florentia Fostira, Olivia Fuentes-Ríos, Encarna B Gómez-García, Sara González, Christopher Haiman, Thomas van Overeem Hansen, Jan Hauke, James Hodge, Chunling Hu, Hongyan Huang, Nur Diana Binte Ishak, Yusuke Iwasaki, Irene Konstantopoulou, Peter Kraft, James Lacey, Conxi Lázaro, Na Li, Weng Khong Lim, Sara Lindstrom, Adriana Lori, Elana Martinez, Alexandra Martins, Koichi Matsuda, Giuseppe Matullo, Simone McInerny, Kyriaki Michailidou, Marco Montagna, Alvaro NA Monteiro, Luigi Mori, Katherine Nathanson, Susan L Neuhausen, Heli Nevanlinna, Janet E Olson, Julie Palmer, Barbara Pasini, Alpa Patel, Maria Piane, Bruce Poppe, Paolo Radice, Alessandra Renieri, Nicoletta Resta, Marcy E Richardson, Toon Rosseel, Kathryn J Ruddy, Marta Santamariña, Elizabeth Santana Dos Santos, Lauren Teras, Amanda E Toland, Amy Trentham-Dietz, Celine M Vachon, Alexander E Volk, Nana Weber-Lassalle, Jeffrey N Weitzel, Lisa Wiesmuller, Stacey Winham, Siddhartha Yadav, Drakoulis Yannoukakos, Song Yao, Valentina Zampiga, Magnus Zethoven, Ze Wen Zhang, Tomas Zima, Amanda B Spurdle, Ana Vega, Maria Rossing, Jesús Del Valle, Arcangela De Nicolo, Eric Hahnen, Kathleen BM Claes, Joanne Ngeow, Yukihide Momozawa, Paul A James, Fergus J Couch, Libor Macurek, Zdenek Kleibl

“DEGS1-related leukodystrophy: a clinical report and review of literature” Clinical Dysmorphology 2023 July 

Melissa Song Ting Wong, Terrence Thomas, Jiin Ying Lim, Sylvia Kam, Jing Xian Teo, Jianhong Ching, Chew Yin Jasmine Goh, Saumya Shekhar Jamuar, Weng Khong Lim, Ai Ling Koh

“The landscape of tolerated genetic variation in humans and primates” Science 2023 June 

Hong Gao, Tobias Hamp, Jeffrey Ede, Joshua G Schraiber, Jeremy McRae, Moriel Singer-Berk, Yanshen Yang, Anastasia SD Dietrich, Petko P Fiziev, Lukas FK Kuderna, Laksshman Sundaram, Yibing Wu, Aashish Adhikari, Yair Field, Chen Chen, Serafim Batzoglou, Francois Aguet, Gabrielle Lemire, Rebecca Reimers, Daniel Balick, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Fabiano R de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi do Amaral, Mariluce Messias, Maria NF da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Thomas Bataillon, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin MD Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Monkol Lek, Shamil Sunyaev, Anne O’Donnell-Luria, Heidi L Rehm, Jinbo Xu, Jeffrey Rogers, Tomas Marques-Bonet, Kyle Kai-How Farh

“A global catalog of whole-genome diversity from 233 primate species” Science 2023 June

Lukas FK Kuderna, Hong Gao, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idrissa S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria NF da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin MD Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Jeffrey Rogers, Kyle Kai-How Farh, Tomas Marques Bonet

“C9orf72 expansions are the most common cause of genetic frontotemporal dementia in a Southeast Asian cohort” Annals of Clinical and Translational Neurology 2023 April 

Yi Jayne Tan, Alisa CW Yong, Jia Nee Foo, Michelle M Lian, Weng Khong Lim, Jacqueline Dominguez, Zhi Hui Fong, Kaavya Narasimhalu, Hui Jin Chiew, Kok Pin Ng, Simon KS Ting, Nagaendran Kandiah, Adeline SL Ng

“Characterizing the genotypic spectrum of retinitis pigmentosa in East Asian populations: a systematic review” Ophthalmic Genetics 2023 March 

Brian Juin Hsien Lee, Yih-Chung Tham, Tien-En Tan, Yasmin Bylstra, Weng Khong Lim, Kanika Jain, Choi Mun Chan, Ranjana Mathur, Chui Ming Gemmy Cheung, Beau J Fenner

“New insights from a multi-ethnic Asian progressive supranuclear palsy cohort” Parkinsonism & related disorders 2023 March

Shen-Yang Lim, Alfand Marl F Dy Closas, Ai Huey Tan, Jia Lun Lim, Yi Jayne Tan, Yuganthini Vijayanathan, Yi Wen Tay, Wai Keong Ng, Ruban Kanesalingam, Pablo Martinez-Martin, Azlina Ahmad Annuar, Lei Cheng Lit, Jia Nee Foo, Weng Khong Lim, Adeline Su Lyn Ng, Eng-King Tan

“The Singapore national precision medicine strategy” Nature Genetics 2023 February 

Eleanor Wong, Nicolas Bertin, Maxime Hebrard, Roberto Tirado-Magallanes, Claire Bellis, Weng Khong Lim, Chee Yong Chua, Philomena Mei Lin Tong, Raymond Chua, Kenneth Mak, Tit Meng Lim, Wei Yang Cheong, Kwee Eng Thien, Khean Teik Goh, Jin-Fang Chai, Jimmy Lee, Joseph Jao-Yiu Sung, Tien Yin Wong, Calvin Woon Loong Chin, Peter D Gluckman, Liuh Ling Goh, Kenneth Hon Kim Ban, Tin Wee Tan, Xueling Sim, Ching-Yu Cheng, Sonia Davila, Neerja Karnani, Khai Pang Leong, Jianjun Liu, Shyam Prabhakar, Sebastian Maurer-Stroh, Chandra Shekhar Verma, Pavitra Krishnaswamy, Rick Siow Mong Goh, Irenaeus Chia, Clarissa Ho, Doreen Low, Suchin Virabhak, Jacklyn Yong, Weiling Zheng, Shih Wee Seow, Yee Kwang Seck, Mingshi Koh, John C Chambers, E Shyong Tai, Patrick Tan

“Genomic landscape of drug binding and pharmacogenetic variation across diverse populations using SNPdrug3D” 2023 January 

Sebastian Maurer-Stroh, Ashar Malik, Dimitar Kenanov, Cheng-Shoong Chong, Mert Burak Ozturk, Maxime Hebrard, Ying Swan Ho, Zhenxun Wang, Vachiranee Limviphuvadh, Jhoann Miyajima, Roberto Magallanes, Xueling Sim, Jin Fang Chai, Sonia Davila, Khung Keong Yeo, Khai Pang Leong, Liuh Ling Goh, Neerja Karnani, Johan Gunnar Eriksson, Ching-Yu Cheng, Tien Wong, Marie Loh, Rinkoo Dalan, Chiea Chuen Khor, Guo-Liang Chew, Weng Khong Lim, Joanne Ngeow, John Chambers, E Shyong Tai, Nicolas Bertin, Chris Soon Heng Tan, Judice Koh, Patrick Tan, Chandra Verma

“Clinical free text to HPO codes” Rare 2023 January 

Gabrielle Stinton, Jane A Lieviant, Sylvia Kam, Jiin Ying Lim, Jasmine Chew-Yin Goh, Weng Khong Lim, Gareth Baynam, Tele Tan, Duc-Son Pham, Saumya Shekhar Jamuar

“Expanding the DARS phenotype: Late-adult onset myelopathy and leukoencephalopathy” Neurology Asia 2023

Ai Huey Tan, Adeline Su Lyn Ng, Norlisah Mohd Ramli, Weng Khong Lim, Peng Loon Cheah, Jing Xian Teo, Jyn Ling Kuan, Yi Jayne Tan, Jia Lun Lim, Elaine Guo Yan Chew, Jia Nee Foo, Khean Jin Goh, Eng-King Tan, Shen-Yang Lim

“Rapid exome sequencing to aid diagnostics in genetic disorders: Implementation and challenges in the Singapore context” Annals of the Academy of Medicine, Singapore 2022 December 

Nikki Fong, Jiin Ying Lim, Breana Cham, Sylvia Kam, Chew Yin Goh, Heming Wei, Yuen Ming Tan, Hai Yang Law, Weng Khong Lim, Ee Shien Tan, Ene Choo Tan, Saumya Shekhar Jamuar

“Analysis of clinically relevant variants from ancestrally diverse Asian genomes” Nature Communications 2022 November

Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C Chambers, E-Shyong Tai, Patrick Tan, Saumya S Jamuar, Joanne Ngeow, Weng Khong Lim

“Prospective Characterization of Progressive Supranuclear Palsy in a Multi-Ethnic Asian Cohort” medRxiv 2022 October

Shen-Yang Lim, Alfand Marl F Dy Closas, Ai Huey Tan, Jia Lun Lim, Yi Jayne Tan, Yuganthini Vijayanathan, Yi Wen Tay, Raihanah binti Abdul Khalid, Wai Keong Ng, Ruban Kanesalingam, Pablo Martinez-Martin, Jia Nee Foo, Weng Khong Lim, Adeline Su Lyn Ng, Eng-King Tan

“Generating patient-derived ascites-dependent xenograft mouse models of peritoneal carcinomatosis” STAR protocols 2022 September

Ying Liu, Wai Har Ng, Hong-Yuan Zhu, Qiu Xuan Tan, Josephine Hendrikson, Joey Wee-Shan Tan, Gillian Ng, Weng Khong Lim, Chin-Ann Johnny Ong

“High-resolution digital phenotypes from consumer wearables and their applications in machine learning of cardiometabolic risk markers: Cohort Study” Journal of Medical Internet Research 2022 July

Weizhuang Zhou, Yu En Chan, Chuan Sheng Foo, Jingxian Zhang, Jing Xian Teo, Sonia Davila, Weiting Huang, Jonathan Yap, Stuart Cook, Patrick Tan, Calvin Woon-Loong Chin, Khung Keong Yeo, Weng Khong Lim, Pavitra Krishnaswamy

“Retinitis pigmentosa associated with the EYS C2139Y variant: an important cause of blindness in East Asian populations.” Retina 2022 May

Choi Mun Chan, Tien-En Tan, Kanika Jain, Yasmin Bylstra, Ranjana S Mathur, Rachael WC Tang GDN, Brian JH Lee, Saumya S Jamuar, Sylvia Kam, Eranga N Vithana, Weng Khong Lim, Beau J Fenner

“Sa1088: DISCOVERY OF NOVEL PROGNOSTIC BIOMARKERS IN ASCITES OF PATIENTS WITH PERITONEAL CARCINOMATOSIS OF GASTROINTESTINAL ORIGIN” Gastroenterology 2022 May

Ying Liu, Josephine Hendrikson, Wai Har Ng, Qiu Xuan Tan, Joey Wee-Shan Tan, Gillian Ng, Nicholas B Shannon, Weng Khong Lim, Kiat Hon Lim, Irene W Tu, Xing-Yi Sarah Ong, Hui Jun Lim, Jolene S Wong, Jimmy B So, Claramae S Chia, Chin-Ann Johnny Ong

“Acute to Subacute Atraumatic Entrapment Neuropathies in Patients With CMT1A: A Report of a Distinct Phenotypic Variant of CMT1A” Frontiers in Neurology 2022 February 

Zhiyong Chen, Monica Saini, Shermyn XM Neo, Peng-Soon Ng, Jasmine S Koh, Kalpana Prasad, Kamal Verma, Sonia Davila, Weng Khong Lim, Ziqun Phua, Michelle M Li, Corrine Kang, Karine SS Tay, Josiah YH Chai

“Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis” Cell Reports Meicine 2022 February 

Josephine Hendrikson, Ying Liu, Wai Har Ng, Jing Yi Lee, Abner Herbert Lim, Jui Wan Loh, Cedric CY Ng, Whee Sze Ong, Joey Wee-Shan Tan, Qiu Xuan Tan, Gillian Ng, Nicholas B Shannon, Weng Khong Lim, Tony KH Lim, Clarinda Chua, Jolene Si Min Wong, Grace Hwei Ching Tan, Jimmy Bok Yan So, Khay Guan Yeoh, Bin Tean Teh, Claramae Shulyn Chia, Khee Chee Soo, Oi Lian Kon, Iain Beehuat Tan, Jason Yongsheng Chan, Melissa Ching Ching Teo, Chin-Ann J Ong

“Family history assessment significantly enhances delivery of precision medicine in the genomics era” Genome medicine 2021 December

Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S Ginsburg, Lori A Orlando, Patrick Tan

“Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth” Cell Reports Medicine 2021 June

Adi L Tarca, Balint Armin Pataki, Roberto Romero, Marina Sirota, Yuanfang Guan, Rintu Kutum, Nardhy Gomez-Lopez, Bogdan Done, Gaurav Bhatti, Thomas Yu, Gaia Andreoletti, Tinnakorn Chaiworapongsa, Sonia S Hassan, Chaur-Dong Hsu, Nima Aghaeepour, Gustavo Stolovitzky, Istvan Csabai, James C Costello

“Variation in predicted COVID‐19 risk among lemurs and lorises” American Journa of Primatology 2021 June

Amanda D Melin, Joseph D Orkin, Mareike C Janiak, Alejandro Valenzuela, Lukas Kuderna, Frank Marrone III, Hasinala Ramangason, Julie E Horvath, Christian Roos, Andrew C Kitchener, Chiea Chuen Khor, Weng Khong Lim, Jessica GH Lee, Patrick Tan, Govindhaswamy Umapathy, Muthuswamy Raveendran, R Alan Harris, Ivo Gut, Marta Gut, Esther Lizano, Tilo Nadler, Dietmar Zinner, Minh D Le, Sivakumara Manu, Clément J Rabarivola, Alphonse Zaramody, Nicole Andriaholinirina, Steig E Johnson, Erich D Jarvis, Olivier Fedrigo, Dongdong Wu, Guojie Zhang, Kyle Kai‐How Farh, Jeffrey Rogers, Tomas Marques‐Bonet, Arcadi Navarro, David Juan, Paramjit S Arora, James P Higham

“Novel optineurin frameshift insertion in a family with frontotemporal dementia and parkinsonism without amyotrophic lateral sclerosis” Frontiers in Neurology 2021 May

Jacqueline Dominguez, Jeryl Tan Yu, Yi Jayne Tan, Arlene Ng, Ma Fe De Guzman, Ma Luisa Daroy, Michelle M Lian, Li Zeng, Jia Nee Foo, Adeline SL Ng

“Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population” Communications biology 2021 May

Xuling Chang, Resham L Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo

“Rapid Exome Sequencing for Critically Ill Children: Implementation and Challenges in the Asian Context” 2021 April 

Nikki Fong, Jiin Ying Lim, Breana Cham, Sylvia Kam, Chew Yin Goh, Heming Wei, Yuen Ming Tan, Hui Jing Ee, Leng Kee Ching, Wendy Low, Jyn Ling Kuan, Hai Yang Law, Juin Yee Kong, Lik Eng Loh, Ai Ling Koh, Teck Wah Ting, Angeline Lai, Ivy Ng, Weng Khong Lim, Ee Shien Tan, Ene Choo Tan, Saumya Shekhar Jamuar

“Transcriptomic convergence despite genomic divergence drive field cancerization in synchronous squamous tumors” 2021 March

Chin-Ann Johnny Ong, Nicholas B Shannon, Weng Khong Lim, Qiu Xuan Tan, Daniel RY Yap, Sze Min Lek, Joey WS Tan, Shih Jia J Tan, Josephine Hendrikson, Wai Har Ng, Ying Liu, Gillian Ng, Kelvin KN Koh, Cedric CY Ng, Vikneswari Rajasegaran, Choon Kiat Ong, Tony KH Lim, Bin Tean Teh, Oi Lian Kon, Claramae S Chia, Khee Chee Soo, N Gopalakrishna Iyer

“Spectrum of germline mutations within fanconi anemia–associated genes across populations of varying ancestry” JNCI Cancer Spectrum 2021 February 

Sock Hoai Chan, Ying Ni, Shao-Tzu Li, Jing Xian Teo, Nur Diana Binte Ishak, Weng Khong Lim, Joanne Ngeow

“High Diagnostic Utility Incorporating a Targeted Neurodegeneration Gene Panel With MRI Brain Diagnostic Algorithms in Patients With Young-Onset Cognitive Impairment With Leukodystrophy” Frontiers in Neurology 2021 February 

Zhiyong Chen, Yi Jayne Tan, Michelle M Lian, Moses Tandiono, Jia Nee Foo, Weng Khong Lim, Nagaendran Kandiah, Adeline SL Ng

“Investigation into the origins of an ancient BRCA1 founder mutation identified among Chinese families in Singapore” Internatinal Journal of Cancer 2021 February 

Tarryn Shaw, Sock Hoai Chan, Jing Xian Teo, Siao Ting Chong, Shao‐Tzu Li, Eliza Courtney, Diana Ishak, Haresh Sankar, Zoe Li Ting Ang, Jianbang Chiang, Marie Loh, Li Zhou, Soo Chin Lee, Hui‐Yuan Yeh, Arun Mouli Kolinjivadi, Weng Khong Lim, Joanne Ngeow

“Variation in predicted COVID-19 risk among lemurs and lorises (preprint)” 2021

Amanda D Melin, Joseph D Orkin, Mareike C Janiak, Alejandro Valenzuela, Lukas FK Kuderna, Frank Marrone III, Hasinala Ramangason, Julie E Horvath, Christian Roos, Andrew C Kitchener, Chiea Chuen Khor, Weng Khong Lim, Jessica GH Lee, Patrick Tan, Govindhaswamy Umapathy, Muthuswamy Raveendran, R Alan Harris, Ivo Gut, Marta Gut, Esther Lizano, Tilo Nadler, Dietmar Zinner, Steig E Johnson, Erich D Jarvis, Olivier Fedrigo, Dongdong Wu, Guojie Zhang, Kyle Kai-How Farh, Jeffrey Rogers, Tomas Marques-Bonet, Arcadi Navarro, David Juan, Paramjit S Arora, James P Higham

“Association of NOTCH2NLC repeat expansions with Parkinson disease” JAMA neurology 2020 December

Dongrui Ma, Yi Jayne Tan, Adeline SL Ng, Helen L Ong, Weiying Sim, Weng Khong Lim, Jing Xian Teo, Ebonne YL Ng, Ee-Chien Lim, Ee-Wei Lim, Ling-Ling Chan, Louis CS Tan, Zhao Yi, Eng-King Tan

“Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients” Circulation: Genomic and Precision Medicine 2020 October

Chee Jian Pua, Nevin Tham, Calvin WL Chin, Roddy Walsh, Chiea Chuen Khor, Christopher N Toepfer, Giuliana G Repetti, Amanda C Garfinkel, Jourdan K Ewoldt, Paige Cloonan, Christopher S Chen, Shi Qi Lim, Jiashen Cai, Li Yang Loo, Siew Ching Kong, Charleston WK Chiang, Nicola Whiffin, Antonio de Marvao, Pei Min Lio, An An Hii, Cheng Xi Yang, Thu Thao Le, Yasmin Bylstra, Weng Khong Lim, Jing Xian Teo, Kallyandra Padilha, Gabriela V Silva, Bangfen Pan, Risha Govind, Rachel J Buchan, Paul JR Barton, Patrick Tan, Roger Foo, James WL Yip, Raymond CC Wong, Wan Xian Chan, Alexandre C Pereira, Hak Chiaw Tang, Saumya Shekhar Jamuar, James S Ware, Jonathan G Seidman, Christine E Seidman, Stuart A Cook

“Phenotypic bases of NOTCH2NLC GGC expansion positive neuronal intranuclear inclusion disease in a Southeast Asian cohort” Clinical Genetics September 2020

Zhiyong Chen, Zheyu Xu, Qianhui Cheng, Yi Jayne Tan, Helen L Ong, Yi Zhao, Weng Khong Lim, Jing Xian Teo, Jia Nee Foo, Hwei Yee Lee, Jeanne MM Tan, Liting Hang, Wai‐Yung Yu, Simon KS Ting, Eng‐King Tan, Tchoyoson CC Lim, Adeline SL Ng

“NOTCH2NLC GGC Repeat Expansions Are Associated with Sporadic Essential Tremor: Variable Disease Expressivity on Long‐Term Follow‐up” Annals of neurology 2020 September

Adeline SL Ng, Weng Khong Lim, Zheyu Xu, Helen L Ong, Yi Jayne Tan, Wei Ying Sim, Ebonne YL Ng, Jing Xian Teo, Jia Nee Foo, Tchoyoson CC Lim, Wai‐Yung Yu, Ling‐Ling Chan, Hwei‐Yee Lee, Zhiyong Chen, Ee‐Wei Lim, Simon KS Ting, Kumar M Prakash, Louis CS Tan, Zhao Yi, Eng‐King Tan

“NOTCH2NLC-linked neuronal intranuclear inclusion body disease and fragile X-associated tremor/ataxia syndrome” Brain 2020 August 

Adeline SL Ng, Zheyu Xu, Zhiyong Chen, Yi Jayne Tan, Weng Khong Lim, Simon KS Ting, Wai Yung Yu, Qian Hui Cheng, Jia Nee Foo, Eng King Tan, Tchoyoson CC Lim

“Evaluation of family health history collection methods impact on data and risk assessment outcomes” Preventive Medicine Reports 2020 June 

R Ryanne Wu, Rehena Sultana, Yasmin Bylstra, Saumya Jamuar, Sonia Davila, Weng Khong Lim, Geoffrey S Ginsburg, Lori A Orlando, Khung Keong Yeo, Stuart A Cook, Patrick Tan

“Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma” Gut 2020 June

Wen Fong Ooi, Amrita M Nargund, Kevin Junliang Lim, Shenli Zhang, Manjie Xing, Amit Mandoli, Jing Quan Lim, Shamaine Wei Ting Ho, Yu Guo, Xiaosai Yao, Suling Joyce Lin, Tannistha Nandi, Chang Xu, Xuewen Ong, Minghui Lee, Angie Lay-Keng Tan, Yue Ning Lam, Jing Xian Teo, Atsushi Kaneda, Kevin P White, Weng Khong Lim, Steven G Rozen, Bin Tean Teh, Shang Li, Anders J Skanderup, Patrick Tan

“An optimised protocol harnessing laser capture microdissection for transcriptomic analysis on matched primary and metastatic colorectal tumours” Scientific Reports 2020 January 

Chin-Ann J Ong, Qiu Xuan Tan, Hui Jun Lim, Nicholas B Shannon, Weng Khong Lim, Josephine Hendrikson, Wai Har Ng, Joey WS Tan, Kelvin KN Koh, Seettha D Wasudevan, Cedric CY Ng, Vikneswari Rajasegaran, Tony Kiat Hon Lim, Choon Kiat Ong, Oi Lian Kon, Bin Tean Teh, Grace HC Tan, Claramae Shulyn Chia, Khee Chee Soo, Melissa CC Teo

"Family History Assessment Significantly Enhances Delivery of Precision Medicine in the Genomics Era" BioRxiv, January 30 2020

Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, KoeiWan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, ChengXi Yang , Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Lori A. Orlando, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg & Patrick Tan.

“Harnessing technology and molecular analysis to understand the development of cardiovascular diseases in Asia: a prospective cohort study (SingHEART)” BioMed Central 2019 December 

Jonathan Yap, Weng Khong Lim, Anders Sahlén, Calvin Woon-Loong Chin, Kenneth Michael Yun-Chi Chew, Sonia Davila, John Allen, Vera Goh, Swee Yaw Tan, Patrick Tan, Carolyn SP Lam, Stuart Alexander Cook, Khung Keong Yeo

“Large-scale whole-genome sequencing of three diverse Asian populations in Singapore” Cell 2019 October

Degang Wu, Jinzhuang Dou, Xiaoran Chai, Claire Bellis, Andreas Wilm, Chih Chuan Shih, Wendy Wei Jia Soon, Nicolas Bertin, Clarabelle Bitong Lin, Chiea Chuen Khor, Michael DeGiorgio, Shanshan Cheng, Li Bao, Neerja Karnani, William Ying Khee Hwang, Sonia Davila, Patrick Tan, Asim Shabbir, Angela Moh, Eng-King Tan, Jia Nee Foo, Liuh Ling Goh, Khai Pang Leong, Roger SY Foo, Carolyn Su Ping Lam, Arthur Mark Richards, Ching-Yu Cheng, Tin Aung, Tien Yin Wong, Huck Hui Ng, Matthew Andrew Ackers-Johnson, Edita Aliwarga, Kenneth Hon Kim Ban, Denis Bertrand, John C Chambers, Dana Leng Hui Chan, Cheryl Xue Li Chan, Miao Li Chee, Miao Ling Chee, Pauline Chen, Yunxin Chen, Elaine Guo Yan Chew, Wen Jie Chew, Lynn Hui Yun Chiam, Jenny Pek Ching Chong, Ivan Chua, Stuart A Cook, Wei Dai, Rajkumar Dorajoo, Chuan-Sheng Foo, Rick Siow Mong Goh, Axel M Hillmer, Ishak D Irwan, Fazlur Jaufeerally, Asif Javed, Justin Jeyakani, John Tat Hung Koh, Jia Yu Koh, Pavitra Krishnaswamy, Jyn Ling Kuan, Neelam Kumari, Ai Shan Lee, Seow Eng Lee, Sheldon Lee, Yen Ling Lee, See Ting Leong, Zheng Li, Peter Yiqing Li, Jun Xian Liew, Oi Wah Liew, Su Chi Lim, Weng Khong Lim, Chia Wei Lim, Tingsen Benson Lim, Choon Kiat Lim, Seet Yoong Loh, Au Wing Lok, Calvin WL Chin, Shivani Majithia, Sebastian Maurer-Stroh, Wee Yang Meah, Shi Qi Mok, Niranjan Nargarajan, Pauline Ng, Sarah B Ng, Zhenyuan Ng, Jessica Yan Xia Ng, Ebonne Ng, Shi Ling Ng, Simon Nusinovici, Chin Thing Ong, Bangfen Pan, Vincent Pedergnana, Stanley Poh, Shyam Prabhakar, Kumar M Prakash, Ivy Quek, Charumathi Sabanayagam, Wei Qiang See, Yee Yen Sia, Xueling Sim, Wey Cheng Sim, Jimmy So, Dinna KN Soon, E Shyong Tai, Nicholas Y Tan, Louis CS Tan, Hong Chang Tan, Wilson Lek Wen Tan, Moses Tandiono, Amanda Tay, Sahil Thakur, Yih Chung Tham, Zenia Tiang, Grace Li-Xian Toh, Pi Kuang Tsai, Lavanya Veeravalli, Chandra S Verma, Ling Wang, Min Rui Wang, Wing-Cheong Wong, Zhicheng Xie, Khung Keong Yeo, Liang Zhang, Weiwei Zhai, Yi Zhao, Jianjun Liu, Chaolong Wang

“Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging” Communications Biology 2019 October

Jing Xian Teo, Sonia Davila, Chengxi Yang, An An Hii, Chee Jian Pua, Jonathan Yap, Swee Yaw Tan, Anders Sahlén, Calvin Woon-Loong Chin, Bin Tean Teh, Steven G Rozen, Stuart Alexander Cook, Khung Keong Yeo, Patrick Tan, Weng Khong Lim

“Bridging the gaps of uncertainty in genetic counselling with ethnic-specific data” European Journal of Human Genetics 2019 July

YM Bylstra, J Kuan, W Lim, B Digambar, J Teo, S Davila, B Teh, S Rozen, E Tan, W Meng, K Yeo, P Tan, S Saw, C Cheng, S Cook, R Foo, S Jamuar

“Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen” Nature Communications 2019 June

Michael P Menden, Dennis Wang, Mike J Mason, Bence Szalai, Krishna C Bulusu, Yuanfang Guan, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, In Sock Jang, Zara Ghazoui, Mehmet Eren Ahsen, Robert Vogel, Elias Chaibub Neto, Thea Norman, Eric KY Tang, Mathew J Garnett, Giovanni Y Di Veroli, Stephen Fawell, Gustavo Stolovitzky, Justin Guinney, Jonathan R Dry, Julio Saez-Rodriguez

"Implementation of genomics in medical practice to deliver precision medicine for an Asian population" NPJ Genomic Medicine, 2019 June 7

Yasmin Bylstra, Sonia Davila, Weng Khong Lim, Ryanne Wu, Jing Xian Teo, Sylvia Kam, Tamra Lysaght, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Patrick Tan & Saumya Jamuar.

"Germline pathogenic variants in homologous recombination and DNA repair genes in an Asian cohort of young-onset colorectal cancer"  JNCI Cancer Spectrum, 2018 December 10

Ming Ren Toh, Jian Bang Chiang, Siao Ting Chong, Sock Hoai Chan, Nur Diana Binte Ishak, Eliza Courtney, Wei Hao Lee, Syed Muhammad Fahmy Bin Syed Abdillah Al, John Carson Allen Jr, Kiat Hon Lim, Sonia Davila, Patrick Tan, Weng Khong Lim, Iain Bee Huat Tan & Joanne Ngeow.

"Ethical frameworks for obtaining informed consent in tumour profiling: an evidence-based case for Singapore" Human genomics, 2018 December 8

Yasmin Bylstra, Tamra Lysaght, Jyothi Thrivikraman, Sangeetha Watson & Patrick Tan.  

"Clinical Relevance of Screening Checklists for Detecting Cancer Predisposition Syndromes in Asian Childhood Tumours"  NPJ Genomic Medicine, 2018 November 15

Sock Hoai Chan, Winston Chew, Nur Diana Ishak, Weng Khong Lim, Shao-Tzu Li, Sheng Hui Tan, Jing Xian Teo, Tarryn Shaw, Kenneth Tou En Chang, Yong Chen, Prasad Iyer, Enrica Ee Kar Tan, Michaela Su-Fern Seng, Mei Yoke Chan, Ah Moy Tan, Sharon Yin Yee Low, Shui Yen Soh, Amos Hong Pheng Loh & Joanne Ngeow.

"Population Genomics in South East Asia Captures Unexpectedly High Carrier Frequency for Treatable Inherited Disorders" Genet In Med, 2018 July 2

Yasmin Bylstra, Jyn Ling Kuan, Weng Khong Lim, Jaydutt Digambar Bhalshankar, Jing Xian Teo, Sonia Davila, Bin Tean Teh, Steve Rozen, Ene-Choo Tan, Wendy Kein Meng Liew, Khung Keong Yeo, Patrick Tan, The SinGapore Incidental Finding (SGIF) study group, Seang Mei Saw, Ching-Yu Cheng, Stuart Cook, Roger Foo & Saumya Shekhar Jamuar.

"Beyond fitness tracking: The use of consumer grade wearable data from normal volunteers in cardiovascular and lipidomics research" PLoS Biol, 2018 February 27

Weng Khong Lim, Sonia Davila, Jing Xian Teo, Chengxi Yang, Chee Jian Pua, Christopher Blo ̈cker, Jing Quan Lim, Jianhong Ching, Jonathan Jiunn Liang Yap, Swee Yaw Tan, Anders Sahle ́n, Calvin Woon-Loong Chin, Bin Tean Teh, Steven G. Rozen, Stuart Alexander Cook, Khung Keong Yeo & Patrick Tan.

"Experience of Asian males communicating cardiac genetic risk within the family"  Journal of Community Genetics, 2018 January 8

Sylvia Kam, Yasmin Bylstra, Laura Forrest, Ivan Macciocca & Roger Foo.

"The draft genome of tropical fruit durian (Durio zibethinus)" Nature Genetics, 2017 October

Bin Tean Teh, Kevin Lim , Chern Han Yong, Cedric Chuan Young Ng, Sushma Ramesh Rao, Vikneswari Rajasegaran, Weng Khong Lim, Choon Kiat Ong , Ki Chan, Vincent Kin Yuen Cheng, Poh Sheng Soh, Sanjay Swarup, Steven G Rozen , Niranjan Nagarajan & Patrick Tan.

"Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas" Scientific Report, 2017 September 6

Sock Hoai Chan , Weng Khong Lim, Nur Diana Binte Ishak, Shao-Tzu Li, Wei Lin Goh, Gek San Tan, Kiat Hon Lim, Melissa Teo, Cedric Ng Chuan Young, Simeen Malik, Mann Hong Tan, Jonathan Yi Hui Teh, Francis Kuok Choon Chin, Sittampalam Kesavan, Sathiyamoorthy Selvarajan, Patrick Tan, Bin Tean Teh, Khee Chee Soo, Mohamad Farid, Richard Quek & Joanne Ngeow.

"Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma" Cancer Discovery, 2017 June 30

Apinya Jusakul, Ioana Cutcutache, Chern Han Yong, Jing Quan Lim, Mi Ni Huang, Nisha Padmanabhan, Vishwa Nellore, Sarinya Kongpetch, Alvin Wei Tian Ng, Ley Moy Ng, Su Pin Choo, Swe Swe Myint, Raynoo Thanan, Sanjanaa Nagarajan, Weng Khong Lim, Cedric Chuan Young Ng, Arnoud Boot, Mo Liu, Choon Kiat Ong, Vikneswari Rajasegaran, Stefanus Lie, Alvin Soon Tiong Lim, Tse Hui Lim, Jing Tan, Jia Liang Loh, John R. McPherson, Narong Khuntikeo, Vajaraphongsa Bhudhisawasdi, Puangrat Yongvanit, Sopit Wongkham, Yasushi Totoki, Hiromi Nakamura, Yasuhito Arai, Satoshi Yamasaki, Pierce Kah-Hoe Chow, Alexander Yaw Fui Chung, London Lucien Peng Jin Ooi, Kiat Hon Lim, Simona Dima, Dan G, Duda, Irinel Popescu, Philippe Broet, Sen-Yung Hsieh, Ming-Chin Yu, Aldo Scarpa, Jiaming Lai, Di-Xian Luo, André Lopes Carvalho, André Luiz Vettore, Hyungjin Rhee, Young Nyun Park, Ludmill B. Alexandrov, Raluca Gordân, Steven G. Rozen, Tatsuhiro Shibata, Chawalit Pairojkul, Bin Tean Teh & Patrick Tan.

 

"Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover" Bone, 2017 April 3

Casey J.Droscha, Cassandra R, Diegel, Nicole J Ethen, Travis A. Burgers, Mitchell J McDonald, Kevin A. Maupin, Agni S. Naidu, Peng Fei Wang, Bin Tin Teh, Bart O. Williams

"Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma" Cancer Discovery, 2017 March 20

Aditi Qamra, Manjie Xing, Nisha Padmanabhan, Jeffrey Jun Ting Kwok, Shenli Zhang, Chang Xu, Yan Shan Leong, Ai Ping Lee Lim, Qianqao Tang, Wen Fong Ooi, Joyce Suling Lin, Tannistha Nandi, Xiaosai Yao, Xuewen Ong, Minghui Lee, Su Ting Tay, Angie Tan Lay Keng, Erna Gondo Santoso, Cedric Chuan Young Ng, Alvin Ng, Apinya Jusakul, Duane Smoot, Hassan Ashktorab, Sun Young Rha, Khay Guan Yeoh, Wei Peng Yong, Pierce K.H. Chow, Weng Hoong Chan, Hock Soo Ong, Khee Chee Soo, Kyoung-Mee Kim, Wai Keong Wong, Steven G. Rozen, Bin Tean Teh , Dennis Kappei, Jeeyun Lee, John Connolly & Patrick Tan.

"Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity" Nature Communications, 2016 September 20

Wen Fong Ooi, Manjie Xing, Chang Xu, Xiaosai Yao, Muhammad Khairul Ramlee, Mei Chee Lim, Fan Cao, Kevin Lim, Deepak Babu, Lai-Fong Poon, Joyce Lin Suling, Aditi Qamra, Astrid Irwanto, James Qu Zhengzhong, Tannistha Nandi, Ai Ping Lee-Lim, Yang Sun Chan, Su Ting Tay, Ming Hui Lee, James O.J. Davies, Wai Keong Wong, Khee Chee Soo, Weng Hoong Chan, Hock Soo Ong, Pierce Chow, Chow Yin Wong, Sun Young Rha, Jianjun Liu, Axel M. Hillmer, Jim R. Hughes, Steve Rozen, Bin Tean Teh, Melissa Jane Fullwood, Shang Li & Patrick Tan

"Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia" Nature Medicine, 2016 May 2

Tomoya Fukawa, Benjamin Chua Yan-Jiang, Jason Chua Min-Wen, Elwin Tan Jun-Hao, Dan Huang, Chao-Nan Qian, Pauline Ong, Zhimei Li, Shuwen Chen, Shi Ya Mak, Wan Jun Lim, Hiro-omi Kanayama, Rosmin Elsa Mohan, Ruiqi Rachel Wang, Jiunn Herng Lai, Clarinda Chua, Hock Soo Ong, Ker-Kan Tan, Ying Swan Ho, Iain Beehuat Tan & Bin Tean Teh