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Top Publications

1. Mishra A, Yao LJ, Wasser M, Khyriem C, Malleret B, McGovern N, Albani S, Chan JKY, Ginhoux F. Reply to Over-celling fetal microbial exposure. Cell. 2021 Nov 24;184(24):5842-5844. doi: 10.1016/j.cell.2021.10.028.

2. Mishra A, Lai GC, Yao LJ, Aung TT, Shental N, Rotter-Maskowitz A, Shepherdson E, Singh GSN, Pai R, Shanti A, Wong RMM, Lee A, Khyriem C, Dutertre CA, Chakarov S, Srinivasan KG, Shadan NB, Zhang XM, Khalilnezhad S, Cottier F, Tan ASM, Low G, Chen P, Fan Y, Hor PX, Lee AKM, Choolani M, Vermijlen D, Sharma A, Fuks G, Straussman R, Pavelka N, Malleret B, McGovern N, Albani S, Chan JKY, Ginhoux F. Microbial exposure during early human development primes fetal immune cells. Cell. 2021 May 25:S0092-8674(21)00574-2. doi: 10.1016/j.cell.2021.04.039.

3. Cheng Y, Gunasegaran B, Singh HD, Dutertre CA, Loh CY, Lim JQ, Crawford JC, Lee HK, Zhang X, Lee B, Becht E, Lim WJ, Yeong J, Chan CY, Chung A, Goh BKP, Chow PKH, Chan JKY, Ginhoux F, Tai D, Chen J, Lim SG, Zhai W, Choo SP, Newell EW. Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma. Immunity. 2021 Jul 10:S1074-7613(21)00257-0. doi: 10.1016/j.immuni.2021.06.013.

4. Mulder K, Patel AA, Kong WT, Piot C, Halitzki E, Dunsmore G, Khalilnezhad S, Irac SE, Dubuisson A, Chevrier M, Zhang XM, Tam JKC, Lim TKH, Wong RMM, Pai R, Khalil AIS, Chow PKH, Wu SZ, Al-Eryani G, Roden D, Swarbrick A, Chan JKY, Albani S, Derosa L, Zitvogel L, Sharma A, Chen J, Silvin A, Bertoletti A, Blériot C, Dutertre CA, Ginhoux F. Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease. Immunity. 2021 Jul 27:S1074-7613(21)00293-4. doi: 10.1016/j.immuni.2021.07.007.

5. Huang JY, Cai S, Huang Z, Tint MT, Yuan WL, Aris IM, Godfrey KM, Karnani N, Lee YS, Chan JKY, Chong YS, Eriksson JG, Chan SY. Analyses of child cardiometabolic phenotype following assisted reproductive technologies using a pragmatic trial emulation approach. Nat Commun. 2021 Sep 23;12(1):5613. doi: 10.1038/s41467-021-25899-4.

6. Zhao Y, Wang J, Liu WN, Fong SY, Shuen TWH, Liu M, Harden S, Tan SY, Cheng JY, Tan WWS, Chan JKY, Chee CE, Lee GH, Toh HC, Lim SG, Wan Y, Chen Q. Analysis and validation of human targets and treatments using a hepatocellular carcinoma-immune humanized mouse model. Hepatology. 2021 Mar 18. doi: 10.1002/hep.31812.

7. Malleret B, El Sahili A, Tay MZ, Carissimo G, Ong ASM, Novera W, Lin J, Suwanarusk R, Kosaisavee V, Chu TTT, Sinha A, Howland SW, Fan Y, Gruszczyk J, Tham WH, Colin Y, Maurer-Stroh S, Snounou G, Ng LFP, Chan JKY, Chacko AM, Lescar J, Chandramohanadas R, Nosten F, Russell B, Rénia L. Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells. Nat Microbiol. 2021 Aug;6(8):991-999. doi: 10.1038/s41564-021-00939-3.

8. Lau, H. X., Z. Chen, Y. H. Chan, E. H. Tham, A. Goh, H. Van Bever, O. H. Teoh, K. H. Tan, F. K. P. Yap, K. M. Godfrey, J. G. Eriksson, Y. S. Chong, B. W. Lee, L. P. Shek and E. X. L. Loo. Predictors of allergic sensitization trajectories and its association with allergic outcomes-results from the GUSTO study. Allergy. 2021 Nov 15.

9. Chaiyasit N, Sahota DS, Ma R, Choolani M, Wataganara T, Sim WS, Chaemsaithong P, Wah YMI, Hui SYA, Poon LC. Prospective Evaluation of International Prediction of Pregnancy Complications Collaborative Network models for Prediction of Preeclampsia: Role of Serum sFlt-1 at 11-13 Weeks' Gestation. Hypertension. 2021 Oct 25:HYPERTENSIONAHA12118021. doi: 10.1161/HYPERTENSIONAHA.121.18021. Online ahead of print.

10. Wei D, Zhang H, Broekman BFP, Chong YS, Shek LP, Yap F, Tan KH, Gluckman PD, Meaney MJ, Fortier MV, Qiu A. Cortical Development Mediates Association of Prenatal Maternal Depressive Symptoms and Child Reward Sensitivity: A Longitudinal Study. J Am Acad Child Adolesc Psychiatry. 2021 Jun 16:S0890-8567(21)00403-2. doi: 10.1016/j.jaac.2021.05.021.

11. Suaini NHA, Loo EX, Peters RL, Yap GC, Allen KJ, Van Bever H, Martino DJ, Goh AEN, Dharmage SC, Colega MT, Chong MFF, Ponsonby AL, Tan KH, Tang MLK, Godfrey KM, Lee BW, Shek LP, Koplin JJ, Tham EH. Children of Asian ethnicity in Australia have higher risk of food allergy and early-onset eczema than those in Singapore. Allergy. 2021 Mar 22. doi: 10.1111/all.14823.

12. Loy SL, Keong Chan DW, Ku CW, Cheung YB, Godfrey KM, Ling Tan KM, Chong YS, Pei-Chi Shek L, Tan KH, Chan SY, Chan JKY, Yap F. Metabolic health status and fecundability in a Singapore preconception cohort study. Am J Obstet Gynecol. 2021 Dec 15:S0002-9378(21)02684-3. doi: 10.1016/j.ajog.2021.11.1374. Online ahead of print.

13. Shen HH, Zhang T, Yang HL, Lai ZZ, Zhou WJ, Mei J, Shi JW, Zhu R, Xu FY, Li DJ, Ye JF, Li MQ. Ovarian hormones-autophagy-immunity axis in menstruation and endometriosis. Theranostics. 2021 Jan 19;11(7):3512-3526. doi: 10.7150/thno.55241.

14. Zhou WJ, Zhang J, Xie F, Wu JN, Ye JF, Wang J, Wu K, Li MQ. CD45RO-CD8+ T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis. Theranostics. 2021 Mar 11;11(11):5330-5345. doi: 10.7150/thno.58337. eCollection 2021.

15. Bhatia A, Palacio M, Wright AM, Yeo GSH. Lower uterine segment scar assessment at 11-14 weeks gestation to screen for placenta accreta spectrum in women with prior Cesarean delivery. Ultrasound Obstet Gynecol. 2021 Jul 12. doi: 10.1002/uog.23734.