Success Stories

Automated EEG Interpretation Software and Integrated Analysis Platform

Supporting Innovation Through Strategic Partnership: How AMII Funding Enabled a Breakthrough in Seizure Detection. 

Patients frequently develop seizures in the neurological intensive care unit (ICU) due to the high prevalence of acute structural brain injuries. Continuous electroencephalogram (EEG) is avaluable tool used to screen for “clinically silent” electrographic seizures - aberrant electrical activitythat disrupts brain function and requires timely treatment for better patient outcomes.

Yet the current process of analysing these prolonged recordings is laborious and time-consuming, requiring experienced neuro technologists or neurologists to manually review hours of data. Existing commercial seizure detection tools have fallen short of meeting clinical needs in the hospitalsdue to the low detection sensitivity.

Recognising this critical gap, the National Neuroscience Institute (NNI) team, in partnership with Mindsigns Health™, sought to transform seizure detection through artificial intelligence. With support from the Academic Medicine Innovation Institute (AMII) Testbedding and Adoption Grant (TAG), the team was able to further validate this NeuroBrowser™ —an automated, cloud-based AI enabled seizure detection software— previously co-developed between NNI and Mindsigns Health™, on prolonged EEG acquisitions at NNI @ Tan Tock Seng Hospital (TTSH) and Singapore General Hospital (SGH).

A Remarkable Achievement

The results speak to the team's innovationand rigorous development approach. NeuroBrowser™ demonstrated superior seizure detection sensitivity compared with commercially available software.Modelling studies are underway, and if cost-effectiveness of software adoption into clinical workflows is demonstrated,this will position NeuroBrowser™ as a game-changing screening tool for rapid detection of potential seizures in the ICU environment, directly impacting the patient care delivery.

Navigating Challenges with Strategic Support

The journey wasn't without its challenges.Working with Mindsigns Health™ brought the agility and innovation typical of startup partnerships but also required careful navigation of risks such as financial uncertainty and dependence on key individuals. The team's success stemmed from early alignment on goals, maintaining agility throughout development, and ensuring continuous post-project innovation to keep the solution clinically relevant. The software has already obtained ISO13485 certification, and a licensing agreement with Mindsigns Health™ is underway. Looking ahead, the successful deployment of NeuroBrowser™ could fundamentally transform neurological care across Singapore's healthcare system and beyond. Following further technical refinement and acquisition of necessary regulatory approvals for clinical deployment, the solution would be positioned for broader adoption across public hospitals, potentially reducing the burden on specialist neurologists, whilst improving patient outcomes through early seizure detection and timely treatment.

Our sincere thanks to Dr Tan Yee Leng and her team for generously sharing their journeys and insights for this project. It is a strong example of how our funding programmes, in this instance, the Academic Medicine Innovation Institute (AMII) Test-bedding and Adoption Grant (TAG) has supported the teams to transform their ideas into tangible results.

Dr Buddy

A*STAR Institute of High Performance Computing (A*STAR IHPC), Singapore General Hospital and the SingHealth Office for Service Transformation have collaborated to develop Dr Buddy, an innovative remote clinical monitoring solution for SingHealth@Home. This system empowers healthcare teams to deliver enhanced care directly to patients' homes, transforming the traditional healthcare delivery model.

Dr Buddy streamlines remote patient monitoring by enabling healthcare professionals to provide timely interventions and personalised care outside hospital settings. The system enhances both patient outcomes and healthcare worker efficiency by facilitating continuous monitoring and early detection of health changes. This innovative solution makes healthcare more accessible and patient-centric, reducing the need for frequent hospital visits whilst maintaining high standards of clinical care.

The partnership exemplifies how inter-agency collaboration and technological innovation can revolutionise healthcare delivery in Singapore, demonstrating the potential for scalable remote monitoring solutions that can be adapted across different healthcare settings.