Denosumab

• Muscle, back, bone and joint pain
• Increased blood pressure
• Increased cholesterol levels
• Nausea or vomiting, constipation
• Slight tiredness

Inform your doctor if any of the following occurs:

• Excessive muscle cramping
• Giddiness or confusion
• Excessive skin dryness, irritation or rashes
• Chest pain or irregular heartbeat
• Fever, pain upon urination, gum pain or gum bleeding
• Severe nausea or vomiting or abdominal pain
• Jaw pain or tooth ache

• Maintain good oral hygiene. Inform your dentist that you are on Denosumab so that appropriate precautions can be taken.
• For females, use effective birth control during treatment and for at least 5 months after the last dose of Denosumab. Inform your doctor if you intend to get pregnant or breastfeed.
• Ensure that you are taking sufficient calcium and vitamin D while you are on Denosumab.

It is a subcutaneous injection which is given at the upper arm, upper thigh or abdomen. You may need to receive one injection every 4 weeks or 6 months depending on your requirements.

If you miss a dose of Denosumab, receive it as soon as possible by rescheduling an administration date with your clinic.

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store in the refrigerator. Do not freeze.;#

​As​ Denosumab exists under two different brand names i.e. Xgeva®, Prolia®, do note the brand that you are currently taking. You should not switch between the two brands unless otherwise instructed by your doctor.