Gefitinib

Iressa®


Uses


What is Gefitinib for?

Gefitinib is a targeted medication that is used for the treatment of non-small cell lung cancer with EGFR gene mutations.

How should I take or use Gefitinib?

It is a tablet to be taken by mouth, once daily. Take with or without food.

What should I do if I forget to take or use Gefitinib?

If you miss a dose of Gefitinib, take it as soon as you can if it is within 12 hours of the missed dose. If more than 12 hours have passed, skip the missed dose and go back to your usual dosing. Do not double dose.


Precaution


What precautions should I take when taking or using Gefitinib?

  • Inform your doctor or pharmacist if you are taking any other medication or supplements e.g. antacids or gastric acid-lowering agents.
  • Use effective birth control during treatment and for at least 2 weeks after stopping Gefitinib.

What food or medication should I avoid when I take or use Gefitinib?

Grapefruit and its juice


Side Effects


What are some common side effects of Gefitinib?

  • Nausea can occur initially
    If nausea occurs, take Gefitinib right after a meal.
  • Loss of appetite
  • Diarrhea
  • Acne-like rash 
    May gradually develop but can sometimes improve and decrease in severity with time. 
  • Dryness of eyes
  • Tiredness and lack of energy may occur

Inform your doctor if any of the following occurs:

  • Allergic reactions – rashes, swelling, breathing difficulty
  • Severe diarrhea
  • Breathlessness, cough and fever
  • Changes in vision, eye pain or irritation
  • Yellowing of the eyes or skin, dark tea-colored urine
  • Severe abdominal pain

Handling


How should I store Gefitinib?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store at room temperature

How should I handle Gefitinib safely?

Do not break or crush the tablet.


For more information


What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on February 2019



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