Ibrutinib

• Nausea and vomiting
• Diarrhea and/or stomach pain
• Tiredness and lack of energy
• Decreased appetite
• Increased risk of bruising or bleeding
  Inform your doctor if you had a recent surgery or if any surgery is planned for you.
• Increased risk of infections
  To minimise your risk of getting infection, avoid crowds or being near people with infection.
• Bone pain or muscle ache
• Mild swelling of the hands or feet

Inform your doctor if any of the following occurs:

• Rapid heartbeat, chest discomfort or shortness of breath
• Unusual light-headedness, giddiness or weakness
• Severe muscle pain or weakness
• Signs of infection – fever, chills, cough, sore throat, pain or difficulty when urinating
• Unusual bruising, bleeding or black tarry stools
• Severe diarrhea

• Inform your doctor or pharmacist if you:
• Have any other medical conditions e.g. heart problems, liver problems
• Are currently taking any other medicines and supplements or intend to start new ones
• Effective birth control measures should be used for both men and women during treatment and for up to 1 month after stopping treatment with Ibrutinib. Inform your doctor if you plan to get or suspect that you are pregnant.

Avoid taking grapefruit and its juice while you are on this medicine.

Take the exact number of capsules as instructed by your doctor. Swallow the capsules whole with water, once daily at approximately the same time each day.

Take with or without food.

If you miss a dose of Ibrutinib, take it as soon as you remember on the same day and return to your regular time the next day. Do not take 2 doses in the same day to make up for a missed dose.

If you overdose on this medicine, inform your doctor immediately.

Do not chew, open or break the capsule.

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#