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Olaparib

Drug Class: Commonly Known As: Category:
PARP Inhibitor Lynparza® Cancer-related

Olaparib - What is it for

Olaparib is a medicine used in the treatment of advanced ovarian cancer.

Olaparib - Side Effects, Precautions, and Contraindications

What side effects can Olaparib cause?

  • Nausea and vomiting
  • Diarrhea and/or stomach discomfort
  • Decreased appetite and taste changes
  • Headache, bone, muscle or back ache
  • Fatigue
  • Rash
  • Decreased blood cells
    This may increase your chances of getting infections, bruising or bleeding. To minimize your risk of getting an infection, avoid crowds or being near people with infection. You may also feel tired with a general lack of energy; do avoid over-exerting yourself with strenous physical activities.

Inform your doctor if any of the following occurs:

  • Pallor, light-headedness, increasing tiredness or weakness
  • Persistent weight loss
  • Signs of infection – fever, chills, cough, sore throat
  • Unusual bruising, bleeding or black stools
  • Gradually worsening cough with wheezing, chest pain or breathing difficulty

Before taking Olaparib, what precautions must I follow?

  • Use effective birth control during and for at least 1 month after stopping treatment with Olaparib. Inform your doctor if you plan to get or suspect that you are pregnant.
  • Do not breast-feed during and for 1 month after the last dose of Olaparib. Inform your doctor if you plan to breast-feed.
  • Inform your doctor of pharmacist if you:
    • Have any other medical conditions e.g kidney or liver problems
    • Are taking any other medicines, herbal products or supplements

What food or medicine must I avoid when I take Olaparib?

  • Avoid the following fruit and their juices while taking Olaparib:
    • Grapefruit
    • Seville orange

Olaparib - Dosage and How to Use

How should Olaparib be used?

Take the exact number of capsules as instructed by your doctor, twice daily at approximately the same time each day. It may be taken with or without food. Swallow the capsules whole.

What should I do if I miss a dose?

If you miss a dose of Olaparib, skip the missed dose and resume your usual dosing time. Do not make up for the missed dose or take two doses at once.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Olaparib - Handling and Storage

How should I handle Olaparib safely?

Do not crush, chew or break the capsules.

How should I store Olaparib?

Keep away from children;#

How should I dispose of Olaparib safely?

Olaparib - Additional Information

Updated on Friday, October 11, 2019

This article is contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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