Main Category Name of Recipient Institution / ACP Project Title Start-Up Dr Yuganthini VIJAYANATHAN National Neuroscience Institute / Neuroscience Spatio-distributed metabolism-related genes potentially govern metabolic rewiring, driving malignancy of heterogenous glioblastoma tumor Start-Up Dr LIU Chang Singapore Eye Research Institute / Ophthalmology & Visual Sciences Evaluation of the safety of terahertz scanning system on corneas: Phase I trial Start-Up Dr Thet Tun AUNG Singapore Eye Research Institute / Ophthalmology & Visual Sciences A novel pre-adapted bacteriophage therapy for methicillin resistant Staphylococcus aureus (MRSA) infections Start-Up Dr FONG Sheng Singapore General Hospital / Medicine Developing molecular biomarkers for dementia staging in a Singapore cohort of geriatric patients Start-Up Dr HO Quan Yao Singapore General Hospital / Medicine Immune monitoring of kidney transplant recipients using torque teno virus Start-Up Dr Henry SOEHARNO Singapore General Hospital / Musculoskeletal Sciences Biomechanical assessment of varying megaprosthesis lengths in distal femoral replacement following tumour excision using finite element modelling Start-Up Dr LEONG Jing Yao Singapore Health Services / Paediatrics Deep antigenic interrogation of T-B cell compartments across individuals with divergent tolerogenic or reactive humoral house dust mite response Transition Project Dr HWANG Le-Ann National Cancer Centre Singapore / Oncology Targeting mutant p53 with mutation-specific antibody-based therapeutics Transition Project Dr Iswaree Devi D/O BALAKRISHNAN National Heart Centre Singapore / Cardiovascular Sciences CLARITI: Cardiomyopathy Linked Ambiguous variant Resolution using artificial InTelligence and Induced pluripotent stem cells Transition Project Asst Prof Simon NUSINOVICI Singapore Eye Research Institute / Ophthalmology & Visual Sciences Biological mechanisms of the protective effect of statin medication for the treatment of age-related macular degeneration (AMD) Transition Project Dr Abby CHOKE Singapore General Hospital / Musculoskeletal Sciences Assessing scaffold-guided bone regeneration using a 3D printed polycaprolactone-tricalcium phosphate (PCL-TCP) composite scaffold in a rodent model Transition Project Dr LI Fang Singapore General Hospital / Musculoskeletal Sciences Development of novel surgical technique for 3D printed patient-specific scaphoid replacement: A computational simulation approach Transition Project Dr Rebecca LIM Qian Ru Singapore General Hospital / Musculoskeletal Sciences Development of a novel implant arthroplasty for distal interphalangeal joints of the hand in the treatment of osteoarthritis Transition Project Asst Prof Robert YAP Tze-Jin Singapore General Hospital / Musculoskeletal Sciences In-vivo validation of a novel synthetic braided scaffold for tendon reconstructive surgery Transition Project Dr THEAN Lai Fun Singapore General Hospital / Surgery Spatial transcriptomics to unravel associations of intratumor microbiome with tumor immune microenvironment and metastasis risk in the early-stage colorectal cancer patients Transition Project Dr Allen WONG Wei Jiat Sengkang General Hospital / Musculoskeletal Sciences The use of a rectus abdominis flap in the primary prevention of anastomotic leaks in the Whipple procedure Special Categories Name of Recipient Institution / ACP Project Title Artificial Intelligience Research (AIR) Dr Annitha ANNATHURAI Sengkang General Hospital / Emergency Medicine Development of an AI Tool to predict ED triage at Sengkang General Hospital Health Services Research – HEARTS (HSR-HEARTS) Dr YEW Jielin Changi General Hospital / Medicine Evaluation of the cost-effectiveness of universal screening for primary aldosteronism, a curable form of hypertension Health Services Research – HEARTS (HSR-HEARTS) Dr NG Yao Yi Kennedy National Cancer Centre Singapore / Oncology Measuring the true cost of cancer: A longitudinal study on productivity cost and health-related quality of life for cancer patients Health Services Research – HEARTS (HSR-HEARTS) Dr KIONG Liqin Kimberley Singapore General Hospital / Surgery Assessing stakeholder needs in the implementation of a head & neck cancer survivorship clinic Health Services Research – HEARTS (HSR-HEARTS) Assoc Prof CHAN Yew Weng Sengkang General Hospital / Anaesthesiology and Perioperative Sciences Tracheal intubation through a video laryngeal mask airway – A preliminary assessment Regenerative Medicine and Cell Therapy (RMCT) Dr CHUE Koy Min Sengkang General Hospital / Surgery Understanding the role of the human metagenome in obesity, sarcopenia and sarcopenic obesity – A pilot study SingHealth Duke-NUS AM & National Health Innovation Centre Singapore (NHIC) Joint MedTech Grant Dr Kelvin GOH Kau Kiat Singapore General Hospital / Pathology Development & validation of a scalable multiplex assay for antibiotic therapeutic drug monitoring in patients with difficult-to-treat gram-negative bacterial infections SingHealth Duke-NUS AM & National Health Innovation Centre Singapore (NHIC) Joint MedTech Grant Dr HO Chi Long Sengkang General Hospital / Radiological Sciences SG Brain: AI-augmented clinical radiology platform for ageing brain abnormality detection, using SG population-based Normative MR Brain Aging Atlas

AM Research Grant Initiative | SingHealth Duke-NUS

The AM Research Grant Initiative provides funding support to deserving translational and clinical research within the SingHealth Duke-NUS Academic Medical Centre (AMC).

You may view our latest AM Research Grant Initiative 2023 Recipients below and find out more about the principal investigators involved and their project titles.

AM Research Grant Initiative Recipients

Main Category	Name of Recipient	Institution / ACP	Project Title
Start-Up	Dr Yuganthini VIJAYANATHAN	National Neuroscience Institute / Neuroscience	Spatio-distributed metabolism-related genes potentially govern metabolic rewiring, driving malignancy of heterogenous glioblastoma tumor
Start-Up	Dr LIU Chang	Singapore Eye Research Institute / Ophthalmology & Visual Sciences	Evaluation of the safety of terahertz scanning system on corneas: Phase I trial
Start-Up	Dr Thet Tun AUNG	Singapore Eye Research Institute / Ophthalmology & Visual Sciences	A novel pre-adapted bacteriophage therapy for methicillin resistant Staphylococcus aureus (MRSA) infections
Start-Up	Dr FONG Sheng	Singapore General Hospital / Medicine	Developing molecular biomarkers for dementia staging in a Singapore cohort of geriatric patients
Start-Up	Dr HO Quan Yao	Singapore General Hospital / Medicine	Immune monitoring of kidney transplant recipients using torque teno virus
Start-Up	Dr Henry SOEHARNO	Singapore General Hospital / Musculoskeletal Sciences	Biomechanical assessment of varying megaprosthesis lengths in distal femoral replacement following tumour excision using finite element modelling
Start-Up	Dr LEONG Jing Yao	Singapore Health Services / Paediatrics	Deep antigenic interrogation of T-B cell compartments across individuals with divergent tolerogenic or reactive humoral house dust mite response
Transition Project	Dr HWANG Le-Ann	National Cancer Centre Singapore / Oncology	Targeting mutant p53 with mutation-specific antibody-based therapeutics
Transition Project	Dr Iswaree Devi D/O BALAKRISHNAN	National Heart Centre Singapore / Cardiovascular Sciences	CLARITI: Cardiomyopathy Linked Ambiguous variant Resolution using artificial InTelligence and Induced pluripotent stem cells
Transition Project	Asst Prof Simon NUSINOVICI	Singapore Eye Research Institute / Ophthalmology & Visual Sciences	Biological mechanisms of the protective effect of statin medication for the treatment of age-related macular degeneration (AMD)
Transition Project	Dr Abby CHOKE	Singapore General Hospital / Musculoskeletal Sciences	Assessing scaffold-guided bone regeneration using a 3D printed polycaprolactone-tricalcium phosphate (PCL-TCP) composite scaffold in a rodent model
Transition Project	Dr LI Fang	Singapore General Hospital / Musculoskeletal Sciences	Development of novel surgical technique for 3D printed patient-specific scaphoid replacement: A computational simulation approach
Transition Project	Dr Rebecca LIM Qian Ru	Singapore General Hospital / Musculoskeletal Sciences	Development of a novel implant arthroplasty for distal interphalangeal joints of the hand in the treatment of osteoarthritis
Transition Project	Asst Prof Robert YAP Tze-Jin	Singapore General Hospital / Musculoskeletal Sciences	In-vivo validation of a novel synthetic braided scaffold for tendon reconstructive surgery
Transition Project	Dr THEAN Lai Fun	Singapore General Hospital / Surgery	Spatial transcriptomics to unravel associations of intratumor microbiome with tumor immune microenvironment and metastasis risk in the early-stage colorectal cancer patients
Transition Project	Dr Allen WONG Wei Jiat	Sengkang General Hospital / Musculoskeletal Sciences	The use of a rectus abdominis flap in the primary prevention of anastomotic leaks in the Whipple procedure

Special Categories	Name of Recipient	Institution / ACP	Project Title
Artificial Intelligience Research (AIR)	Dr Annitha ANNATHURAI	Sengkang General Hospital / Emergency Medicine	Development of an AI Tool to predict ED triage at Sengkang General Hospital
Health Services Research – HEARTS (HSR-HEARTS)	Dr YEW Jielin	Changi General Hospital / Medicine	Evaluation of the cost-effectiveness of universal screening for primary aldosteronism, a curable form of hypertension
Health Services Research – HEARTS (HSR-HEARTS)	Dr NG Yao Yi Kennedy	National Cancer Centre Singapore / Oncology	Measuring the true cost of cancer: A longitudinal study on productivity cost and health-related quality of life for cancer patients
Health Services Research – HEARTS (HSR-HEARTS)	Dr KIONG Liqin Kimberley	Singapore General Hospital / Surgery	Assessing stakeholder needs in the implementation of a head & neck cancer survivorship clinic
Health Services Research – HEARTS (HSR-HEARTS)	Assoc Prof CHAN Yew Weng	Sengkang General Hospital / Anaesthesiology and Perioperative Sciences	Tracheal intubation through a video laryngeal mask airway – A preliminary assessment
Regenerative Medicine and Cell Therapy (RMCT)	Dr CHUE Koy Min	Sengkang General Hospital / Surgery	Understanding the role of the human metagenome in obesity, sarcopenia and sarcopenic obesity – A pilot study
SingHealth Duke-NUS AM & National Health Innovation Centre Singapore (NHIC) Joint MedTech Grant	Dr Kelvin GOH Kau Kiat	Singapore General Hospital / Pathology	Development & validation of a scalable multiplex assay for antibiotic therapeutic drug monitoring in patients with difficult-to-treat gram-negative bacterial infections
SingHealth Duke-NUS AM & National Health Innovation Centre Singapore (NHIC) Joint MedTech Grant	Dr HO Chi Long	Sengkang General Hospital / Radiological Sciences	SG Brain: AI-augmented clinical radiology platform for ageing brain abnormality detection, using SG population-based Normative MR Brain Aging Atlas