PRECISE Clinical Implementation Pilots (CIP)

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Objective

Technological advances have allowed us to interrogate the human genome in ways that were never possible before. These tests can help us better predict and diagnose disease and provide optimal outcomes with current therapy. Singapore has initiated a National Precision Medicine programme (NPM) in 2017.

In Singapore's Research Innovation and Enterprise (RIE) 2025 plan, the NPM is a national translational programme prioritised under the Human Health Potential (HHP) domain. One of the goals is to facilitate the incorporation of genetic/genomic tests into clinical pathways that improve patient outcomes while maintaining sustainable per capita cost, optimizing healthcare experiences for both providers and patients.

The Precision Health Research Singapore (PRECISE) is pleased to launch a call for proposals to support Clinical Implementation Pilot (CIP) projects for clinical application of genetic/genomic tests to diagnose, manage and/or treat a specific patient cohort(s) and/or population for targeted conditions or disease phenotypes, with the overarching aim of the CIP grant call to:

1. Achieve progress towards the RIE 2025 HHP goals;

2. Inform policy decision-making for implementation in local healthcare system

Funding Details

• The grant award is up to S$1.5M over a period of 2 years per project.

• Additional supplementary funding quantum of up to S$3M will be available to support collaborative supplementary project(s) between shortlisted applicants. There is no provision of indirect costs from grant.

Eligibility Criteria

1. Each project team must consist of one "Clinical co-PI" and one "Health Economist co-PI". They are expected to lead the CIP project overall (i.e., main points of contact with PRECISE for post-award engagement on implementation and economic evaluation of programme).　

2. Between the "Clinical co-PI" and "Health Economist co-PI", a "Corresponding PI" is to be identified who will be additionally responsible for all administration and accountable for funding-related matters; this will include, but not limited to, managing partnerships with additional collaborators ("co-PIs") whom are included as part of the bigger project team.

3. "Corresponding PI" should hold a primary appointment in, and be salaried by a Public Health Institution, Academic Medical Centre, Institute of Higher Learning or Research Institute in Singapore.

4. There is no restriction to the number of "co-PIs" that can be included as part of the bigger project team.

5. Project teams are also expected to work closely with PRECISE health economics team and its network for the implementation and economic evaluation of the programme.

Submission

Applicants are to submit their completed application (1 WORD softcopy) using the attached application form 'CIP-Application-Form-v8.0' to CIP secretariat at CIP@precis.cris.sg through Host Institution's research office by 23 September 2021 (Thursday), 5pm.

Contact Person

CIP Secretariat

Email: CIP@precis.cris.sg 　

Additional Information

Please find the PRECISE CIP's website here.

CIP-Application-Form-v8.0.docx

CIP_Virtual_Roadshow_Materials_v4.0-Final-1.pdf

Company-Resource-List_v0.3_CAA289721_R1.pdf