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Tamoxifen

Drug Class: Commonly Known As: Category:
Selective Estrogen Receptor Modulator (SERM) Nolvadex® Cancer-related

Tamoxifen - What is it for

Tamoxifen is a medicine that is used to treat breast cancer. It works by blocking the effect of the female hormone, estrogen.

Tamoxifen - Side Effects, Precautions, and Contraindications

What side effects can Tamoxifen cause?

  • Nausea can sometimes occur initially
    If nausea occurs, take your tablets right after a meal.
  • Hot flushes
    If this occurs, take your tablets at bedtime.
  • Swelling of the leg or feet (water retention)
  • Menstrual irregularities

Inform your doctor if any of the following occurs:

  • Signs of blood clot over a vein e.g. calf tenderness, warmth, swelling, redness
  • Sudden onset of cough, chest pain or shortness of breath
  • Changes in eye sight
  • For women: unexpected bleeding or discharge from the vagina

Before taking Tamoxifen, what precautions must I follow?

  • Inform your doctor or pharmacist if you have any other medical conditions e.g. history of blood clots.
  • Use effective birth control while taking Tamoxifen. Inform your doctor if you plan to get or suspect that you are pregnant.
  • Do not breastfeed. Inform your doctor if you intend to breastfeed while taking Tamoxifen.

What food or medicine must I avoid when I take Tamoxifen?

Grapefruit and its juice.

Tamoxifen - Dosage and How to Use

How should Tamoxifen be used?

It is a tablet, to be taken by mouth. It may be taken with or without food, with a glass of water or juice.

What should I do if I miss a dose?

If you miss a dose of Tamoxifen, take it as soon as you remember if it is within a few hours of your missed dose. If it is too near to your next dose, skip the missed dose and go back to your usual dosing time. Do not double the dose.

What should I do if I overdose?

If you overdose on Tamoxifen, inform your doctor immediately.

Tamoxifen - Handling and Storage

How should I handle Tamoxifen safely?

How should I store Tamoxifen?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Tamoxifen safely?

Tamoxifen - Additional Information

Click here for more information on the use of Tamoxifen as Anti-Estrogen type of drugs for men.

Updated on Wednesday, February 27, 2019

This article is contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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