Imaging Capabilities

PET subsystem - High resolution imaging of functional processes in small animals (mice and rats) with the use of radiotracers.

• Axial FOV: Single FOV: 10cm
• Multi FOV: up to 28cm
• Spatial resolution:
  - 0.7mm (Tera-tomo 3D PET reconstruction engine)
  -1.2mm (with 2D FBP according to NEMA standards)
• Temporal resolution: 1.7ns
• Crystal material: LYSO

MRI subsystem - Imaging of soft tissue morphology.

• Magnet strength: 1 Tesla
• Image resolution: 100 µm in-vivo
• Homogeneity: <2 ppm for mouse, <4 ppm for rat   

CT subsystem - High resolution imaging of anatomical structures in small animals (mice and rats) using X-Ray

• Maximum FOV: 121x96mm
• Spatial resolution (FWHM): <30µm @ 10% MTF
• Helical scanning: up to 28cm
• Variable zoom magnification: up to 6x

SPECT subsystem - High resolution spatial imaging of anatomical structures in small animals (mice and rats) using gamma rays.

• Detector FOV: 27x27cm
• Spatial resolution: ≤275µm (with Tera-Tomo 3D SPECT)
• Whole body resolution: 0.85mm for mouse, 1.4mm for rat

For high resolution imaging of lying or awake animals, including 3 types of animal positioning systems as well as parallel imaging of small animals.

CT subsystem

• Maximum FOV: ~20 x 15 cm
• Spatial resolution (FWHM): <30µm @ 10% MTF
• Scanning: Circular / helical
• Magnification: X1.5

PET subsystem

• Axial FOV: Single FOV: 15 cm
• Transaxial FOV: 20 cm
• Spatial resolution:
  -1 mm (Tera-Tomo 3D PET reconstruction engine)
  -1.5mm (with FBP according to NEMA standards)
• Temporal resolution:1.0ns

High sensitivity In-vivo optical (fluorescence and bioluminescence) imaging for small animals.

• 3D tomographic reconstruction
• High throughput with 5 mice at 23cm FOV
• High resolution to 20 microns with 3.9cm FOV
• 28 high efficiency filters: 10 narrow band Ex filters (415 - 760nm with 30nm bandwidth)
• Multispectral imaging with superior spectral unmixing properties
• Ideal for distinguishing multiple bioluminescent and fluorescent reporters
• Ability to import and automatically co-register CT or MRI images yielding functional and anatomical context

Real time x-ray imaging of large animals.

• C-arm orbital movement: 132° (-42° to +90°)
• C-arm angulation: ±190°
• C-arm horizontal movement: 20 cm
• C-arm immersion depth: 73 cm
• C-arm swivel range: ±10°
• C-arm vertical movement: 38 cm, motorized
• Camera with CCD sensor: 1034 (H) x 1024 (V)

Portable Real time x-ray imaging of large animals.

• Footprint (L x W x H): 131cm x 63cm x 133cm
• Max. focal spot height: 190cm
• Max. horizontal tube extension: 110cm

For non-invasive image acquisition of large animals.

• Frequency: 50/60 Hz
• Operating modes: B-mode, M-mode, Color flow, Power Doppler Imaging (PDI), PW & CW Doppler, 2D volume mode
• Horizontal/vertical viewing angle of +/- 170 ̊

Real time and non-invasive image acquisition capabilities for in-vivo small animal studies,or visualisation of molecular events or quantification of tumour size.

• Resolution: up to 30 µm
• Image modes: B / M / PW / 2D Doppler (color/power) / 3D / Contrast / Elasticity
• Frequency:
  -PB406e probe: Center frequency 40MHz
  -PB207e probe: Center frequency 20 MHz
• Field of view:
  -Depth up to 39 mm (20 MHz probe)
  -Width up to 23 mm

For performing minimally invasive surgery (MIS) through small incisions on large animals.

• Image sensor: 3 X 1/3”
• Aspect ratio: 16:9
• Picture elements: 1920x1080 (2,073,600) pixels
• Scan method: progressive
• Image refresh rate: 50 Hz
• Focal length: 14 to 30 mm