Asst Prof Loy See Ling

Dr Loy See Ling is a Junior Principal Investigator at KKH and an Assistant Professor at Duke-NUS Medical School. Her research focuses on life course epidemiology and nutrition, with a specific interest in food timing, chronobiology, fertility, and maternal-child metabolic health. She also holds a Visiting Professorship at Columbia University Irving Medical Center.

Previously, she was a Research Fellow at KKH and Adjunct Investigator at the Singapore Institute of Clinical Sciences, A*STAR. She led projects on fertility, maternal-child nutrition, and metabolic outcomes, contributing significantly to the GUSTO and S-PRESTO cohort studies. Her work resulted in numerous publications and early-career awards, including the NMRC Open Fund–Young Individual Research Grant (OF-YIRG).

She served as Associate Faculty at the Singapore Institute of Technology, lecturing and supervising research projects in the Dietetics and Nutrition programme.

She contributes to clinical translation through initiatives such as the Healthy Early Life Moments in Singapore programme and is a principal or co-investigator on several NMRC-funded projects, including the Transition Award and Population Health Research Grant.

She also contributes to science communication through newsletters and outreach articles, and has supported collaborative clinical guideline development.

She has received over 30 awards, including fellowships and travel awards, presentation and publication prizes.

• PhD in Human Nutrition (Malaysia) 2014
• BSc Dietetics (Malaysia) 2009

• Visiting Professor, Columbia University Irving Medical Center, USA 2025 – Present
• Junior Principal Investigator, Department of Reproductive Medicine, KKH 2022 – Present
• Maternal and Child Health Research Committee, KKH 2022 – Present
• Associate Faculty, Singapore Institute of Technology 2021 – 2025
• Assistant Professor, Duke-NUS Medical School, Duke-NUS 2020 – Present
• Senior Research Fellow, Department of Reproductive Medicine, KKH 2020 – 2022
• Research Fellow, Department of Reproductive Medicine, KKH 2014 – 2019
• Life member, Nutrition Society Malaysia, Malaysia 2013 – Present
• Life member, Malaysian Association for the Study of Obesity, Malaysia 2013 – Present

• SingHealth Excellence Awards (SHEA) Distinguished Young Researcher Award, SingHealth, 2025
• International Visiting Professorship Award, American Heart Association, 2025
• 10-year Long Service Award, KKH, 2025
• SingHealth Publish Award, 2024
• Transition Award, NMRC, 2024
• Population Health Research Grant Open Category, NMRC, 2023
• SingHealth Publish Award, 2022
• Temasek Foundation Cares grant, 2020
• SingHealth Publish Award, 2019
• Best Poster Presentation, International Society of Behavioural Nutrition and Physical Activity, 2018
• Open Fund Young Individual Research Grant, NMRC, 2018
• SingHealth Publish Award, 2016
• Best Oral Award (Clinical Research, Senior), SingHealth Duke-NUS Scientific Congress, 2016
• Rising Star Award, Asia-Oceania Conference on Obesity, Japan, 2015
• Excellent Achievement in Best Research, Universiti Sains Malaysia, 2015
• PhD Thesis Award, Nutrition Society Malaysia, 2014
• Fellowship, International Union of Nutritional Sciences, 2014
• Young Researcher Award, Nestlé Nutrition Institute, 2013
• Travel Awards for Junior Investigators, Developmental Origins of Health and Disease, 2013
• Best Research Award: PhD (medical sciences), Universiti Sains Malaysia, 2013
• Postgraduate Research Training Fellowship, University of Queensland, Australia, 2013
• Travel Grant, Birth Cohort Consortium of Asia, Taiwan, 2012
• Excellent Achievement in Journal Publication, Universiti Sains Malaysia, 2012
• Best Oral Presentation, Julius Centre, University of Malaya, 2012
• Fellowship Award, Southeast Asian Ministers of Education Organization, Regional Centre for Food and Nutrition, Indonesia, 2011, 2012
• Publication Prize in Maternal Nutrition Research, Nutrition Society Malaysia, 2012
• Grant-in-aid program, Tanita Healthy Weight Community Trust Award, Japan, 2011
• Postgraduate (PhD) Fellowship, Universiti Sains Malaysia, 2010

• Life course epidemiology (preconception, pregnancy, postnatal, and early childhood)
• Nutritional epidemiology (dietary pattern, micronutrient status, and supplementation)
• Chronobehaviour (timing of eating, sleep, movement, and light exposure)
• Reproductive health (female and male fertility, couple-centric assessment and intervention)
• Metabolic health (obesity and diabetes)

• Feasibility of home-based dim-light melatonin onset and home blood pressure monitoring: A pilot study, 2025–2026
• Evaluation of the Healthy Early Life Moments in Singapore (HELMS) program during preconception, 2025–2028
• Menstrual phenotypes and iron status among adolescents in Singapore, 2024–2026
• Associations of metabolic indicators and circadian behaviour with reproductive outcomes in women trying to conceive, 2024–2027
• Investigating male factors and reproductive outcomes in Singapore, 2024–2027
• Effect of the 6P metabolic assessment and intervention tool on metabolic outcomes in women trying to conceive, 2024–2026
• Evaluating a digital feeding and lifestyle behaviour intervention in infants: RCT, 2024–2027
• Development of a mobile app to promote healthy eating in early life, 2024–2025
• Functional roles of plasma micronutrients in women receiving preconception nutrition intervention, 2023–2026
• Early Nurtures in Determining Offspring Well-being (ENDOW), 2022–2024
• Appetitive traits, feeding practices and infant growth in Malaysia, 2022–2024
• Development and validation of a healthy lifestyle tool in infants and toddlers, 2022–2024
• Autologous PRP infusion in women with ovarian insufficiency, 2022–2024
• Evaluation of physicality and sleep interventions in preconception, 2021–2025
• Use of letrozole or mifepristone for medical termination of pregnancy, 2021–2023
• Chrononutrition and glycaemia in Malaysian prediabetes, 2021–2024
• PICSI in IVF for poor fertilisation history, 2021–2024
• Healthy Early Life Moments in Singapore (HELMS), 2021–2025
• Vitamin D supplementation in overweight and obese pregnant women, 2021–2024
• Perinatal outcomes of interpregnancy weight change, 2020–2022
• Metabolic health in Asian women and their children, 2021–2026
• Pathophysiology of preterm birth and low birth weight in preconception cohort, 2020–2022
• CRADLE: Community-enabled readiness for first-time families, 2019–2024
• Epidemiology of gestational weight gain in low-middle income countries, 2020–2025
• Maternal night-eating pattern and glucose tolerance during pregnancy, 2018–2022
• Maternal tobacco exposure, oxidative stress and body fat composition, 2011–2013

• Chronofertility: integrating multi-timescale chronobiology into fertility research and clinical care. Loy SL, Pek JW, Ku CW, Chen LW, Tekwe CD, Abdalla M, Zoh RS, Yap F, Chan JKY. Fertil Steril. 2025. (in press)
• A qualitative study on nutrition and well-being of healthcare shift workers. Mohd Fahmi Teng NI, Ngelayang E, Md Said N, Juliana N, Mohd Azmi NAS, Chen LW, Loy SL. Sci Rep. 2025. (in press)
• Association between chrononutrition, sleep behaviours, and glycaemic outcomes in individuals with prediabetes: findings from the Chrono-DMTM study. Chong GY, Kaur S, Talib RA, Loy SL, Tan HY, Abdullah R, Mahmud H, Siah WY, Tan LK, Kee CC, Koo HC. Chronobiol Int. 2025. (in press)
• One-carbon metabolism, insulin resistance, and fecundability in a Singapore Preconception Cohort Study. Ku CW, Chan HG, Sia AL, Huang C, Quek J, Cheung YB, Tan KML, Lai JS, Godfrey KM, Chan JKY, Yap F, Loy SL. Am J Clin Nutr. 2025 Jul;122(1):335–343.
• Associations of >1-hour versus ≤1-hour meal timing variability (eating jetlag) with plasma glycemic parameters and continuous glucose monitoring measures among pregnant females: A prospective cohort study. Chen YE, Ku CW, Chong MFF, Yap F, Chan JKY, Loy SL*, Chen LW* (*co-last). Am J Clin Nutr. 2025 Jul;122(1):244–254.
• Comparison of two measurement error-correction approaches for assessing the association between choline intake and coronary heart disease prevalence among US community-dwelling adults. Huo C, Luan Y, Zoh RS, Gletsu-Miller N, Carter SJ, Frey G, Lin HC, Bidulescu A, Loy SL, Abdalla M, Tekwe CD. Ann Epidemiol. 2025 Jul;S1047-2797(25)00155-3.
• Development and psychometric validation of a clinical instrument for infant feeding and lifestyle evaluation. Chan D, Lin J, Zheng R, Ong C, Ku CW, Loo BKG, Chan JKY, Chua MC, Yap F, Loy SL. J Pediatr Gastroenterol Nutr. 2025 May;80(5):870–879.
• Development and validation of a novel self-assessment tool for breastfeeding mothers. Ong C, Loy SL, Pang C, Lee S, Krishnan S, Chan D, Ku CW, Chan JKY, Yap F, Chua MC. Int Breastfeed J. 2025 Apr;20(1):25.
• Caregiver feeding practices and eating behaviors in infants and toddlers in Singapore. Quah PL, Chan D, Loy SL, Ong C, Chua MC, Yap F, Tan CHN, Chia MYH, Chua TBK, Tan KH. Front Nutr. 2025 Mar;12:1540031.
• Scoping review protocol: The chrononutrition factors in association with glycemic outcomes in adult population. Chong GY, Kaur S, Talib RA, Loy SL, Tan HY, Mok KHW, Chen LW, Siah WY, Chee YY, Lem EMJ, Koo HC. PLoS One. 2025 Feb;20(2):e0313931.
• Investigating male factors and their relationships with reproductive health outcomes: a case-control study protocol for Towards Optimal Fertility, Fathering, and Fatherhood studY (TOFFFY) in Singapore. Ku CW, Pek JW, Cheung YB, Tharmalingam Durgahshree M, Chan M, Lee YH, Godfrey KM, Yap F, Chan JKY, Loy SL. BMJ Open. 2025 Jan;15(1):e088143.
• Early continuous glucose monitoring-derived glycemic patterns are associated with subsequent insulin resistance and gestational diabetes mellitus development during pregnancy. Ku CW, Zheng RT, Tan HY, Lim JYQ, Chen LW, Cheung YB, Godfrey KM, Chan JKY, Yap F, Lek N, Loy SL. Diabetol Metab Syndr. 2024 Nov;16:271.
• Knowledge, attitudes, and practices of paediatric medical officers and registrars on the Developmental Origins of Health and Disease in a tertiary women’s and children’s hospital. Chan D, Heng TYJ, Zheng R, Chang S, Loy SL, Ku CW, Chua MC, Yap F. BMC Med Educ. 2024 Oct;24(1):1097.
• Development and validation of an evaluation questionnaire for the Healthy Early Life Moments in Singapore (HELMS) Program. Ku CW, Yusoff MA, Ng ECB, Zheng RT, Yap F, Chan JKY, Loy SL. J Pers Med. 2024 Sep;14(9):989.
• Maternal pregnancy diet quality, night eating, and offspring metabolic health: The GUSTO study. Chen LW, Loy SL, Tint MT, Michael N, Ong YY, Toh JY, Gluckman PD, Tan KH, Chong YS, Godfrey KM, Eriksson JG, Yap F, Lee YS, Chong MFF. Pediatr Res. 2024 Sep;doi:10.1038/s41390-024-03574-w.
• Breastfeeding practices and postpartum weight retention in an Asian cohort. Loy SL, Chan HG, Teo J, Chua MC, Chay OM, Ng KC. Nutrients. 2024 Jul;16(13):2172.
• Relation of preconception eating behaviours to dietary pattern trajectories and gestational weight gain from preconception to late pregnancy. Loh J, Loy SL, Appannah G, Colega MT, Godfrey KM, Yap F, Chong YS, Eriksson JG, Chan JKY, Chan SY, Chong MFF, Lai JS. Appetite. 2024 Jul;198:107336.
• Scoping review: Exploring the relationship between chrononutrition and glycemic responses in the adult population. Chong GY, Kaur S, Ruzita AT, Mok KHW, Tan HY, Loy SL, Chen LW, Siah WY, Lim GP, Chee YY, Lem EMJ, Koo HC. Chronobiol Int. 2024 Jun;41(6):904–923.
• The impact of excluding adverse neonatal outcomes on the creation of gestational weight gain charts among women from low-and middle-income countries with normal and overweight BMI. Carrilho TRB, Wang D, Hutcheon JA, Wang M, Fawzi WW, Kac G, members of the GWG Pooling Project Consortium (Loy SL). Am J Clin Nutr. 2024 Jun;119(6):1465–1474.
• Holistic preconception care: providing real-time guidance via a digital platform to optimise maternal and child health. Ku CW, Tan YB, Tan SI, Ku CO, Godfrey KM, Tan KH, Chan SY, Yang L, Yap F, Loy SL*, Chan JKY* (*co-last). Ann Acad Med Singap. 2024 Mar;52:306–317.
• Preliminary assessment of the Healthy Early Life Moments (HELMS) webinars in empowering Developmental Origins of Health and Disease (DOHaD) concept among healthcare professionals – a pragmatic serial cross-sectional study. Ku CW, Ng RRG, Chang TY, Lim CHF, Zheng RT, Ma W, Chua MC, Chan JKY, Yap FKP, Loy SL. J Perinat Med. 2024 Feb;52(4):406–415.
• Umbilical cord plasma lysophospholipids and triacylglycerols associated with birthweight percentiles. Wong G, Narasimhan K, Cheong WF, Ng S, Aris IM, Loy SL, Bendt AK, Tan KH, Yap FKP, Shek LP, Chong YS, Gluckman PD, Godfrey KM, Lee YS, Wenk MR, Karnani N, Chan SY. Nutrients. 2024 Jan;16(2):274.
• The effect of vitamin D supplementation in pregnant women with overweight and obesity: A randomised controlled trial. Ku CW, Lee AJW, Oh B, Lim CHF, Chang TY, Yap F, Chan JKY, Loy SL. Nutrients. 2023 Dec;16(1):146.
• Associations of predominant night-eating with plasma glycemic status and continuous glucose monitoring measures among pregnant women. Loy SL*, Ku CW* (*co-first), Zheng RT, Lim CHF, Chang TY, Chen LW, Cheung YB, Tan KH, Chong MFF, Chan JKY, Lek N, Yap F. Clin Nutr. 2023 Oct;42:2320–2327.
• Suboptimal gestational weight gain and neonatal outcomes in low and middle income countries: individual participant data meta-analysis. Perumal N, Wang D, Darling AM, Liu E, Wang M, Ahmed T, Christian P, Dewey KG, Kac G, Kennedy SH, Subramoney V, Briggs B, Fawzi WW; GWG Pooling Project Consortium (Loy SL). BMJ. 2023 Sep;382:e072249.
• Risk factors for inadequate and excessive gestational weight gain in 25 low-and middle-income countries: An individual-level participant meta-analysis. Darling AM, Wang D, Perumal N, Liu E, Wang M, Ahmed T, Christian P, Dewey KG, Kac G, Kennedy SH, Subramoney V, Briggs B, Fawzi WW; members of the GWG Pooling Project Consortium (Loy SL). PLoS Med. 2023 Jul;20:e1004236.
• Preconception sleep quality moderates the association between preconception hair cortisol levels and mental health in pregnant women. Jafar NKA, Tham EKH, Eng DZH, Yeo S, Rifkin-Graboi A, Gooley JJ, Loy SL, Eriksson JG, Chong YS, Tan KH, Chan JKY, Chen H, Shek LP, Gluckman PD, Yap F, Meaney MJ, Broekman BFP, Kee MZL, Cai S. J Affect Disord. 2023 May;334:187–196.
• Longitudinal analysis of patterns and correlates of physical activity and sedentary behavior from preconception to postpartum: The Singapore Preconception Study of Long-Term Maternal and Child Outcomes cohort. Chu AHY, Padmapriya N, Tan SL, Goh CMJL, Chong YS, Shek LP, Tan KH, Gluckman PD, Yap FKP, Lee YS, Loy SL, Chan JKY, Godfrey KM, Eriksson JG, Chan SY, Bernard JY, Müller-Riemenschneider F. J Phys Act Health. 2023 May;1–10.
• Longitudinal characterization of determinants associated with obesogenic growth patterns in early childhood. Michael N, Gupta V, Fogel A, Huang J, Chen L, Sadananthan SA, Ong YY, Aris IM, Pang WW, Yuan WL, Loy SL, Thway Tint M, Tan KH, Chan JK, Chan SY, Shek LP, Yap F, Godfrey K, Chong YS, Gluckman P, Velan SS, Forde CG, Lee YS, Eriksson JG, Karnani N. Int J Epidemiol. 2023 Apr;52(2):426–439.
• Distribution and association of interpregnancy weight change with subsequent pregnancy outcomes: a cohort study using electronic medical records. Ku CW, Cheng TS, Ku CO, Zhou KX, Cheung YB, Godfrey K, Han WM, Yap F, Chan JKY, Loy SL. Sci Rep. 2023 Mar;13:4843.
• Developmental Origins of Health and Disease: current knowledge, attitude and practice of Obstetrics & Gynaecology residents, paediatric residents, and medical students. Ku CW, Kwek LK, Loo RSX, Xing HK, Tan RCA, Leow SH, Yap F, Chan JKY, Loy SL. Women Health. 2023 Mar;63:175–185.
• Time-to-conception and clinical pregnancy rate with a combined myo-inositol, probiotics and micronutrient supplement: NiPPeR Controlled Trial. Chan SY, Barton SJ, Loy SL, Chang HF, Titcombe P, Wong JT, Ebreo M, Ong J, Tan KML, Nield H, El-Heis S, Kenealy T, Chong YS, Baker PN, Cutfield W, Godfrey KM, NiPPeR Study Group. Fertil Steril. 2023 Feb;119(6):1031–1042.
• Modifiable risk factor score and fecundability in a preconception cohort in Singapore. Loy SL*, Ku CW* (*co-first), Tiong MMY, Ng CST, Cheung YB, Godfrey KM, Lim SX, Colega MT, Lai JS, Chong YS, Shek LPC, Tan KH, Chan SY, Chong MFF, Yap F, Chan JKY. JAMA Netw Open. 2023 Feb;6(2):e2255001.
• Exposure to perfluoroalkyl substances and women’s fertility outcomes in a Singaporean population-based preconception cohort. Cohen NJ, Yao M, Midya V, India-Aldana S, Mouzica T, Andra SS, Narasimhan S, Meher AK, Arora M, Chan JKY, Chan SY, Loy SL, Minguez-Alarcon L, Oulhote Y, Huang J, Valvi D. Sci Total Environ. 2023 Feb;873:162267.
• Plasma lipidomic profiling reveals metabolic adaptations to pregnancy and signatures of cardiometabolic risk: a preconception and longitudinal cohort study. Chen L, Mir SA, Bendt AK, Chua EWL, Narasimhan K, Tan KML, Loy SL, Tan KH, Shek L, Chan J, Yap F, Meany MJ, Chan SY, Chong YS, Gluckman PD, Eriksson JG, Karnani N, Wenk MR. BMC Med. 2023 Feb;21:53.
• Chrononutrition during pregnancy and its association with maternal and offspring outcomes: a systematic review and meta-analysis of Ramadan and non-Ramadan studies. Chen YE, Loy SL, Chen LW. Nutrients. 2023 Feb;15:756.
• Translation, validation and reliability of the Malay version chrononutrition profile-questionnaire (CPQ-M) in Malaysian adult populations. Chong GY, Kaur S, Ruzita AT, Loy SL, Siah WY, Tan HY, Singh S, Rosmiza A, Hanisah M, Lee YH, Koo HC. Biol Rhythm Res. 2023 Jan;54:164–185.
• Dietary supplement intake and fecundability in a Singapore preconception cohort study. Ku CW, Ku CO, Tay LPC, Xing HK, Cheung YB, Godfrey KM, Colega MT, Teo C, Tan KML, Chong YS, Shek LPC, Tan KH, Chan SY, Lim SX, Chong MFFC, Yap F, Chan JKY, Loy SL. Nutrients. 2022 Dec;14:5110.
• Effects of an integrated mobile health lifestyle intervention among overweight and obese women planning for pregnancy in Singapore: protocol for the single-arm healthy early life moments in Singapore (HELMS) study. Chan JKY, Ku CW, Loy SL, Godfrey KM, Fan Y, Chua MC, Yap F. BMJ Open. 2022 Dec;12:e061556.
• Associations of maternal and fetoplacental factors with prehypertension/hypertension in early childhood. Michael N, Sadananthan SA, Yuan WL, Ong YY, Loy SL, Huang J, Tint MT, Natarajan P, Choo J, Ling LH, Kramer M, Godfrey KM, Gluckman P, Tan KH, Eriksson J, Chong YS, Lee YS, Karnani N, Yap F, Shek L, Fortier M, Moritz K, Chan SY, Velan SS, Wlodek M. J Hypertens. 2022 Nov;40:2171–2179.
• Retinal microvasculature and risk of spontaneous abortion in multiethnic Southeast Asian women. Li LJ, Du R, Loy SL, Chong YS, Chan JKY, Wong TY, Eriksson JG, Huang Z, Zhang C. Fertil Steril. 2022 Oct;118:748–757.
• Chronotype, chrononutrition and glucose tolerance among prediabetic individuals: research protocol for a prospective longitudinal study Chrono-DMTM. Chong GY, Kaur S, Ruzita AT, Loy SL, Tan HY, Singh S, Rosmiza A, Hanisah M, Siah WY, Koo HC. BMC Prim Care. 2022 Aug;23:193.
• A golden thread approach to transforming maternal and child health in Singapore. Yap F, Loy SL, Ku CW, Chua MC, Godfrey KM, Chan JKY. BMC Pregnancy Childbirth. 2022 Jul;22:561.
• Automated machine learning (AutoML)-derived preconception predictive risk model to guide early intervention for gestational diabetes mellitus. Kumar M, Ang LT, Hang P, Ng M, Tan K, Loy SL, Tan KH, Chan JKY, Godfrey KM, Chan SY, Chong YS, Eriksson JG, Feng M, Karnani N. Int J Environ Res Public Health. 2022 Jun;19:6792.
• Nocturnal lifestyle behaviours and risk of poor sleep during pregnancy. Ku CW, Loo RSX, Tiong MMY, Eng SYC, Cheung YB, Ong LS, Tan KH, Chong MF, Chan JKY, Yap F, Loy SL. Nutrients. 2022 Jun;14:2348.
• Metabolic health status and fecundability in a Singapore preconception cohort study. Loy SL, Chan DWK, Ku CW, Cheung YB, Godfrey KM, Tan KML, Chong YS, Shek LPC, Tan KH, Chan SY, Chan JKY, Yap F. Am J Obstet Gynecol. 2022 May;226:P714.e1–e16.
• Maternal diet, nutritional status and infant birth weight in Malaysia: a scoping review. Jan Mohamed HJ, Loy SL, Mitra AK, Kaur S, Teoh AN, Abd Rahman SH, Amarra MS. BMC Pregnancy Childbirth. 2022 Apr;22:294.
• Tracking of dietary patterns between pregnancy and 6 years post-pregnancy in a multiethnic Asian cohort: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study. Lee YQ, Colega M, Sugianto R, Lai JS, Godfrey KM, Tan KH, Shek LP, Loy SL, Müller-Riemenschneider F, Padmapriya N, Chong YS, Eriksson JG, Chan JKY, Chan SY, Tai BC, Chong MF. Eur J Nutr. 2022 Mar;61:985–1001.
• Developing a lifestyle intervention program for overweight or obese preconception, pregnant and postpartum women using qualitative methods. Ku CW, Leow SH, Ong LS, Erwin C, Ong I, Ng XW, Tan JJX, Yap F, Chan JKY, Loy SL. Sci Rep. 2022 Feb;12:2511.
• Prepregnancy adherence to plant-based diet indices and exploratory dietary patterns in relation to fecundability. Lim SX, Loy SL, Colega MT, Lai JS, Godfrey KM, Lee YS, Tan KH, Yap F, Shek LP, Chong YS, Eriksson JG, Chan JKY, Chan SY, Chong MF. Am J Clin Nutr. 2022 Feb;115(2):559–569.
• Development and validation of a lifestyle behavior tool in overweight and obese women through qualitative and quantitative approaches. Ku CW, Loo RSX, Lim CJE, Tan JJX, Ho JEW, Han WM, Ng XW, Chan JKY, Yap F, Loy SL. Nutrients. 2021 Dec;13(12):4553.
• Influence of red blood cell indices on the performance of HbA1c in detecting dysglycaemia in women of reproductive age. Loy SL, Lin J, Cheung YB, Sreedharan AV, Chin X, Godfrey KM, Tan KH, Shek L, Chong YS, Leow M, Khoo CM, Lee YS, Chan SY, Lek N, Chan J, Yap F. Sci Rep. 2021 Oct;11(1):20850.
• Maternal meal irregularities during pregnancy and lifestyle correlates. Loo RSX, Yap F, Ku CW, Cheung YB, Tan KH, Chan JKY, Loy SL. Appetite. 2021 Oct;168:105747.
• Retinal microvasculature and time to pregnancy in a multi-ethnic pre-conception cohort in Singapore. Huang L, Loy SL, Chen WQ, Eriksson JG, Chong YS, Huang Z, Chan JKY, Wong TY, Kramer M, Zhang C, Li LJ. Hum Reprod. 2021 Oct;36(11):2935–2947.
• Increasing nausea and vomiting of pregnancy is associated with sex-dependent differences in early childhood growth: the GUSTO mother-offspring cohort study. Ong J, Sadananthan SA, Soh SE, Ng S, Yuan WL, Aris IM, Tint MT, Michael N, Loy SL, Tan KH, Godfrey KM, Shek LP, Yap F, Lee YS, Chong YS, Chan SY. BMC Pregnancy Childbirth. 2021 Aug;21:578.
• Comparative epidemiology of gestational diabetes in ethnic Chinese from Shanghai birth cohort and Growing Up in Singapore Towards healthy Outcomes cohort. Loo EXL, Zhang Y, Yap QV, Yu G, Soh SE, Loy SL, Lau HX, Chan SY, Shek LP, Luo ZC, Yap FKP, Tan KH, Chong YS, Zhang J, Eriksson JG. BMC Pregnancy Childbirth. 2021 Aug;21:566.
• Discovery and validation of peritoneal endometriosis biomarkers in peritoneal fluid and serum. Loy SL, Zhou J, Cui L, Tan TY, Ee TX, Chern BSM, Chan JKY, Lee YH. Reprod Biomed Online. 2021 Jul;S1472-6483(21)00342-4.
• Maternal height, gestational diabetes mellitus and pregnancy complications. Chu AHY, Yuan WL, Loy SL, Soh SE, Bernard JY, Tint MT, Ho-Lim SST, Goh H, Ramasamy A, Kumar M, Goh C, Ang LT, Shek LP, Chong YS, Tan KH, Su LL, Biswas A, Yap F, Lee YS, Chi C, Godfrey KM, Eriksson JG, Chan SY. Diabetes Res Clin Pract. 2021 Jul;178:108978.
• Maternal circulating SPINT1 is reduced in small-for-gestational age pregnancies at 26 weeks: Growing Up in Singapore Towards health Outcomes (GUSTO) cohort study. Kaitu'u-Lino TJ, Tong S, Walker SP, MacDonald TM, Cannon P, Nguyen TV, Sadananthan SA, Tint MT, Ong YY, Loy SL, Gluckman PD, Chong YS, Godfrey KM, Chan SY, Tan KH, Lee YS, Michael N, Eriksson JG, Wlodek ME. Placenta. 2021 Jul;110:24–28.
• Risk score to stratify miscarriage risk levels in preconception women. Choo XH, Ku CW, Cheung YB, Godfrey KM, Chong YS, Shek LPC, Tan KH, Tan TC, Nadarajah S, Yap FKP, Colega MT, Chong MFF, Chan SY, Loy SL*, Chan JKY* (*co-last). Sci Rep. 2021 Jun;11:12111.
• Female sexual function and fecundability in a Singapore preconception cohort study. Loy SL, Ku CW, Cheung YB, Godfrey KM, Chong YS, Shek LPC, Tan KH, Yap FKP, Bernard JY, Chen HY, Chan SY, Tan TY, Chan JKY. BMC Pregnancy Childbirth. 2021 Jun;21:444.
• Temporal association of maternal weight gain with early-term and preterm birth and low birth weight babies. Hamid Jan JM, Lim PY, Loy SL, Chang KH, Abdullah AFL. J Chin Med Assoc. 2021 Jul 1;84(7):722-727.
• Combined analysis of gestational diabetes and maternal weight status from pre-pregnancy through post-delivery in future development of type 2 diabetes. Chen LW, Soh SE, Tint MT, Loy SL, Yap F, Tan KH, Lee YS, Shek LP, Godfrey KM, Gluckman PD, Eriksson JG, Chong YS, Chan SY. Sci Rep. 2021 Mar;11:5021.
• A community-enabled readiness for first 1000 days learning ecosystem (CRADLE) for first-time families: study protocol of a three-arm randomised controlled trial. Loy SL, Thilagamangai, Teo J, Chan SW, Abdul Razak NK, Chay OM, Ng KC. Trials. 2021 Mar;22:191.
• Validation of self-collected buccal swab and saliva as a diagnostic tool for COVID-19. Ku CW, Shivani D, Kwan JQT, Loy SL, Erwin C, Ko KKK, Ng XW, Oon L, Thoon KC, Kalimuddin S, Chan JKY. Int J Infect Dis. 2021 Jan;S1201-9712:32604–32607.
• Plasma glycemic measures and fecundability in a Singapore preconception cohort study. Loy SL, Ku CW, Lai AEQ, Choo XH, Ho AHM, Cheung YB, Godfrey KM, Chong YS, Gluckman PD, Shek LPC, Tan KH, Yap FKP, Chan SY, Chan JKY. Fertil Steril. 2021 Jan;115(1):138–147.
• Cohort profile: Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO). Loo EXL, Soh SE, Loy SL, Ng S, Tint MT, Chan SY, Huang JY, Yap F, Tan KH, Chern BSM, Tan HH, Meaney MJ, Karnani N, Godfrey KM, Lee YS, Chan JKY, Gluckman PD, Chong YS, Shek LP, Eriksson JG; S-PRESTO Study Group. Eur J Epidemiol. 2021 Jan;36:129–142.
• Association of cord blood thyroid-stimulating hormone levels with maternal, delivery and infant factors. Tan KML, Chu AHY, Loy SL, Rajadurai VS, Ho CKM, Chong YS et al. Ann Acad Med Singap. 2020 Dec;49:937–947.
• Attitude and perceptions towards COVID-19 among pregnant women in Singapore: a cross-sectional survey. Lee RWK, Loy SL, Yang L, Chan JKY, Tan LK. BMC Pregnancy Childbirth. 2020 Nov;20:675.
• Mismatch between poor fetal growth and rapid postnatal weight gain in the first 2 years of life is associated with higher blood pressure and insulin resistance without increased adiposity in childhood: the GUSTO cohort study. Ong YY, Suresh A, Aris IM, Tint MT, Yuan WL, Huang J, Chan YH, Ng S, Loy SL, Valen SS, Fortier M, Godfrey KM, Shek L, Tan KH, Gluckman PD, Fabian Y, Choo JTL, Ling LH, Tan K, Chen L, Karnani N, Chong YS, Eriksson J, Wlodek M, Chan SY, Lee YS, Michael N. Int J Epidemiol. 2020 Oct;49:1591–1603.
• Chrononutrition during pregnancy: a review on maternal night-time eating. Loy SL, Loo RSX, Godfrey KM, Chong YS, Shek LPC, Tan KH, Chong MFF, Chan JKY, Yap F. Nutrients. 2020 Sep;12:2783.
• Anthropometric measures and HbA1c to detect dysglycaemia in Asian women planning pregnancy: preconception cohort study. Chu AHY, Aris IM, Ng S, Loy SL, Bernard JY, Tint MT, et al. Sci Rep. 2020 Jun;10:9228.
• Determinants of intramyocellular lipid accumulation in early childhood. Michael N, Gupta V, Sadananthan SA, Sampathkumar A, Chen L, Pan H, Tint MT, Lee KJ, Loy SL, Aris IM, Shek LP, Yap FKP, Godfrey KM, Leow MK, Lee YS, Kramer MS, Henry CJ, Fortier MV, Seng Chong Y, Gluckman PD, Karnani N, Velan SS. Int J Obes (Lond). 2020 May;44(5):1141–1151.
• Timeliness of childhood vaccination coverage: the Growing Up in Singapore Towards Healthy Outcomes study. Loy SL, Cheung YB, Chan JKY, Soh SE, Godfrey KM, Tan KH, Shek LPC, Chong YS, Lek N, Yap F, Teoh OH, Yung CF, Thoon KC. Prev Sci. 2020, Apr;21(3):283–292.
• Associations of circadian eating pattern and diet quality with substantial postpartum weight retention. Loy SL, Cheung YB, Colega MT, Chia A, Han CY, Godfrey KM, Chong YS, Shek LPC, Tan KH, Lek N, Chan JKYC, Chong MFF, Yap F. Nutrients. 2019 Nov;11(11):E2686.
• Maternal night-eating pattern and glucose tolerance during pregnancy: study protocol for a longitudinal study. Loy SL, Cheung YB, Chong MFF, Falk MR, Lek N, Lee YS, Tan KH, Chern B, Yap F, Chan J. BMJ Open. 2019 Sep;9(10):e030036.
• Associations of maternal night-time eating and sleep duration on length of gestation and preterm delivery. Loy SL, Cheung YB, Cai S, Colega MT, Godfrey KM, Chong YS, Shek LPC, Tan KH, Chong MFF, Yap F, Chan JKY. Clin Nutr. 2019 Aug;S0261-5614(19):33030–33034.
• Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age: the S-PRESTO study. Bernard JY, Ng S, Natarajan P, Loy SL, Aris IM, Tint MT, Chong YS, Shek L, Chan J, Godfrey KM, Khoo CM, Leow MK, Müller-Riemenschneider F, Chan SY. Diabet Med. 2019 Jul;36(7):888–897.
• Sex-specific longitudinal associations of screen viewing time in children at 2–3 years with adiposity at 3–5 years. Padmapriya N, Aris IM, Tint MT, Loy SL, Cai S, Tan KH, Shek LP, Chong YS, Godfrey KM, Gluckman PD, Lee YS, Saw SM, Yap F, Kramer MS, Bernard JY, Müller-Riemenschneider F. Int J Obes (Lond). 2019 Jul;43(7):1334–1343.
• Iron status and risk factors of iron deficiency among pregnant women in Singapore: a cross-sectional study. Loy SL, Lim LM, Chan SY, Tan PT, Chee YL, Quah PL, Chan JKY, Tan KH, Yap F, Godfrey KM, Shek LP, Chong MF, Kramer MS, Chong YS, Chi C. BMC Public Health. 2019 Apr;19(1):397.
• Macronutrient composition and food groups associated with gestational weight gain: the GUSTO study. Lai JS, Soh SE, Loy SL, Colega M, Kramer MS, Chan JKY, Tan TC, Shek LPC, Yap FKP, Tan KH, Godfrey KM, Chong YS, Chong MFF. Eur J Nutr. 2019 Apr;58(3):1081–1094.
• Association between early life weight gain and abdominal fat partitioning at 4.5 years is sex-, ethnicity- and age-dependent. Sadananthan SA, Tint MT, Michael N, Aris IM, Loy SL, Lee KJ, Shek LP, Yap FKP, Tan KH, Godfrey KM, Leow MK, Lee YS, Kramer MS, Gluckman PD, Chong YS, Karnani N, Henry CJ, Fortier MV, Velan SS. Obesity. 2019 Mar;27(3):470–478.
• Female adiposity and time-to-pregnancy: a multi-ethnic prospective cohort. Loy SL, Cheung YB, Soh SE, Ng S, Tint MT, Aris IM, Bernard JY, Chong YS, Godfrey KM, Shek LP, Tan KH, Lee YS, Tan HH, Chern BSM, Lek N, Yap F, Chan SY, Chi C, Chan JKY. Hum Reprod. 2018 Nov;33(11):2141–2149.
• Association of elective and emergency caesarean delivery on early childhood overweight at 12 months of age. Cai MJ, Loy SL, Tan KH, Godfrey KM, Gluckman PD, Chong YS, Shek LPC, Cheung YB, Lek N, Lee YS, Chan SY, Chan JKY, Yap F, Ang SB. JAMA Netw Open. 2018 Nov;1(7):e185025.
• Maternal serum and breast milk adiponectin: the association with infant adiposity development. Mohamad M, Loy SL, Lim PY, Wang Y, Soo KL, Jan Mohamed HJ. Int J Environ Res Public Health. 2018 Jun;15(6):E1250.
• Impact of adopting the 2013 World Health Organization criteria for diagnosis of gestational diabetes in a multi-ethnic Asian cohort: a prospective study. Chi C*, Loy SL* (*co-first), Chan SY, Choong C, Cai S, Soh SE, Tan KH, Yap F, Gluckman PD, Godfrey KM, Shek LP, Chan JKY, Kramer MS, Chong YS. BMC Pregnancy Childbirth. 2018 Mar;18(1):69.
• Early life secondhand smoke exposure assessed by hair nicotine biomarker may reduce children's neurodevelopment at 2 years of age. Mohamed NN, Loy SL, Lim PY, Al Mamun A, Jan Mohamed HJ. Sci Total Environ. 2018 Jan;610–611:147–153.
• Relation of plasma tryptophan concentrations during pregnancy to maternal sleep and mental well-being: the GUSTO cohort. van Lee L, Cai S, Loy SL, Tham EKH, Yap FKP, Godfrey KM, Gluckman PD, Shek LPC, Teoh OH, Goh DYT, Tan KH, Chong YS, Meaney MJ, Chen H, Broekman BFP, Chong MFF. J Affect Disord. 2018 Jan;225:523–529.
• Age-related nomograms for antral follicle count and anti-Mullerian hormone for subfertile Chinese women in Singapore. Loy SL, Cheung YB, Fortier MV, Ong CL, Tan HH, Nadarajah S, Chan JKY, Viardot-Foucault V. PLoS One. 2017 Dec;12(12):e0189830.
• Sleep and dietary patterns in pregnancy: findings from the GUSTO cohort. van Lee L, Chia AR, Loy SL, Colega M, Tham EKH, Cai S, Yap F, Godfrey KM, Teoh OH, Goh D, Tan KH, Chong YS, Broekman BFP, Chong MFF. Int J Environ Res Public Health. 2017 Nov;14(11):E1409.
• Associations of physical activity and sedentary behavior during pregnancy with gestational diabetes mellitus among Asian women in Singapore. Padmapriya N, Bernard JY, Liang S, Loy SL, Cai S, Zhe IS, Kwek K, Godfrey KM, Gluckman PD, Saw SM, Chong YS, Chan JKY, Müller-Riemenschneider F. BMC Pregnancy Childbirth. 2017 Oct;17(1):364.
• Determination of phospholipid concentrations in breast milk and serum using a high performance liquid chromatography–mass spectrometry–multiple reaction monitoring method. Ma L, MacGibbon AKH, Jan Mohamed HJ, Loy SL, Rowan A, McJarrow P, Fong BY. Int Dairy J. 2017 Aug;71:50–59.
• Maternal night-fasting interval during pregnancy is directly associated with neonatal head circumference and adiposity in girls but not boys. Loy SL, Wee PH, Colega MT, Cheung YB, Aris IM, Chan JKY, Godfrey KM, Gluckman PD, Tan KH, Shek LP, Chong YS, Natarajan P, Müller-Riemenschneider F, Lek N, Rajadurai VS, Tint MT, Lee YS, Chong MF, Yap F. J Nutr. 2017 Jul;147(7):1384–1391.
• Circadian feeding patterns of 12-month-old infants. Wee PH, Loy SL, Toh JY, Tham EKH, Cheung YB, Godfrey KM, Gluckman PD, Saw SM, Chong YS, Lek N, Chan JKY, Goh DYT, Chong MF, Yap F. Br J Nutr. 2017 Jun;117(12):1702–1710.
• Plasma omega-3 fatty acids in pregnancy are inversely associated with postpartum weight retention in a multi-ethnic Asian cohort. Loy SL, Ng MJH, Cheung YB, Godfrey KM, Calder PC, Lek N, Yap F, Müller-Riemenschneider F, Natarajan P, Chong YS, Tan KH, Shek LP, Chong MF, Chan JKY. Am J Clin Nutr. 2017 May;105(5):1158–1165.
• Associations between caesarean delivery and allergic outcomes: results from the GUSTO study. Lee EXL, Sim JZT, Loy SL, Goh A, Chan YH, Tan KH, Yap F, Gluckman PD, Godfrey KM, Van Bever H, Lee BW, Chong YS, Shek LP, Koh MJA, Ang SB. Ann Allergy Asthma Immunol. 2017 May;118(5):636–638.
• Plasma vitamin D status is associated with poor sleep quality and night-time eating at mid-pregnancy in Singapore. Cheng TS, Loy SL, Cheung YB, Cai S, Colega MT, Godfrey KM, Chong YS, Tan KH, Shek LP, Lee YS, Lek N, Chan JK, Chong MF, Yap F. Nutrients. 2017 Mar;9(4):E340.
• Maternal circadian eating time and frequency are associated with blood glucose concentrations during pregnancy. Loy SL, Chan JK, Wee PH, Colega MT, Cheung YB, Godfrey KM, Kwek K, Saw SM, Chong YS, Natarajan P, Müller-Riemenschneider F, Lek N, Chong MF, Yap F. J Nutr. 2017 Jan;147(1):70–77.
• Association of physical activity and sedentary behavior with depression and anxiety symptoms during pregnancy in a multiethnic cohort of Asian women. Padmapriya N, Bernard JY, Liang S, Loy SL, Shen Z, Kwek K, Godfrey KM, Gluckman PD, Chong YS, Saw SM, Meaney MJ, Chen H, Müller-Riemenschneider F. Arch Womens Ment Health. 2016 Dec;19(6):1119–1128.
• Demographic characteristics, health behaviors before and during pregnancy, and pregnancy and birth outcomes in mothers with different pregnancy planning status. Cheng TS*, Loy SL* (*co-first), Cheung YB, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Yap F, Chan JKY, Lek N. Prev Sci. 2016 Nov;17(8):960–969.
• Higher hair nicotine level in children compared to mother living with smoking father in Malaysia. Mohamed NN, Loy SL, Man CN, Al-Mamun A, Jan Mohamed HJ. Environ Health Prev Med. 2016 Nov;21(6):572–578.
• Association of parental body mass index before pregnancy on infant growth and body composition: evidence from a pregnancy cohort study in Malaysia. Zalbahar N, Jan Mohamed HJ, Loy SL, Najman J, McIntyre HD, Mamun A. Obes Res Clin Pract. 2016 Sep;10 Suppl 1:S35–S47.
• Predominantly nighttime feeding and weight outcomes in infants. Cheng TS*, Loy SL* (*co-first), Toh JY, Cheung YB, Chan JK, Godfrey KM, Gluckman PD, Saw SM, Chong YS, Lee YS, Lek N, Chong MF, Yap F. Am J Clin Nutr. 2016 Aug;104(2):380–388.
• Predominantly night-time feeding and maternal glycaemic levels during pregnancy. Loy SL*, Cheng TS* (*co-first), Colega MT, Cheung YB, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Padmapriya N, Müller-Riemenschneider F, Lek N, Yap F, Chong MF, Chan JKY. Br J Nutr. 2016 May;115(9):1563–1570.
• Sexually dimorphic response to feeding mode in the growth of infants. Cheng TS*, Loy SL* (*co-first), Cheung YB, Chan JKY, Pang WW, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Lek N, Yap F. Am J Clin Nutr. 2016 Feb;103(2):398–405.
• Singaporean mothers’ perception of their three-year-old child’s weight status: a cross-sectional study. Cheng TS*, Loy SL* (*co-first), Cheung YB, Chan JKY, Tint MY, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Yap F, Lek N. PLoS One. 2016 Jan;11(1):e0147563.
• Characteristics associated with the consumption of malted drinks among Malaysian primary school children: findings from the MyBreakfast study. Hamid Jan JM, Loy SL, Mohd Nasir MT, Norimah AK, Tan SY, Appukutty M, Abdul Razak N, Thielecke F, Hopkins S, Ong MK, Ning C, Tee ES. BMC Public Health. 2015 Dec;15:1322.
• Association of maternal vitamin D status with glucose tolerance and caesarean section in a multi-ethnic Asian cohort: the Growing Up in Singapore Towards Healthy Outcomes study. Loy SL, Lek N, Yap F, Soh SE, Padmapriya N, Tan KH, Biswas A, Yeo GS, Kwek K, Gluckman PD, Godfrey KM, Saw SM, Müller-Riemenschneider F, Chong YS, Chong MF, Chan JK. PLoS One. 2015 Nov;10(11):e0142239.
• Determination of ganglioside concentrations in breast milk and serum from Malaysian mothers using a high performance liquid chromatography–mass spectrometry–multiple reaction monitoring method. Ma L, MacGibbon AKH, Jan Mohamed HJ, Loy SL, Rowan A, McJarrow P, Fong BY. Int Dairy J. 2015 Oct;49:62–71.
• Prevalence and determinants of overweight, obesity and type 2 diabetes in adults in Malaysia. Hamid Jan JM, Yap RWK, Loy SL, Norris S, Biesma R, Aagaard-Hansen J. Asia Pac J Public Health. 2015 Mar;27(2):123–135.
• Maternal serum and breast milk vitamin D levels: findings from the Universiti Sains Malaysia Pregnancy Cohort Study. Hamid Jan JM, Rowan A, Fong B, Loy SL. PLoS One. 2014 Jul;9(7):e100705.
• The effects of prenatal oxidative stress levels on infant adiposity development during the first year of life. Loy SL, Sirajudeen KNS, Hamid Jan JM. J Dev Orig Health Dis. 2014 Apr;5(2):142–151.
• The Universiti Sains Malaysia Birth Cohort Study. Loy SL, Hamid Jan JM. Health Environ J. 2014 Jan;5(1):50–64.
• Associations between prenatal nicotine exposure, oxidative stress and postpartum visceral fat. Loy SL, Hamid Jan JM. Women Health. 2014 Jan;54(2):145–160.
• Association between maternal food group intake and birth size. Loy SL, Marhazlina M, Hamid Jan JM. Sains Malays. 2013 Oct;42(11):1633–1640.
• Relative validity of dietary patterns assessed with a food frequency questionnaire in pregnancy. Loy SL, Hamid Jan JM. Int J Food Sci Nutr. 2013 Sep;64(6):668–673.
• Ramadan bazaar and Ramadan buffet: the possible influence on eating behavior and health among Malaysian Muslims. Hamid Jan JM, Nurul Hidayah N, Loy SL. J Fasting Health. 2013 Jul;1(2):43–45.
• Oxidative stress in early life and later obesity development. Loy SL, Sirajudeen KNS, Hamid Jan JM. Malays J Nutr. 2013;19(3):383–399.
• Increase in maternal adiposity and poor lipid profile is associated with oxidative stress markers during pregnancy. Loy SL, Sirajudeen KNS, Hamid Jan JM. Prev Med. 2013 Jan;57 Suppl:S41–S44.
• Higher intake of fruits and vegetables in pregnancy is associated with birth size. Loy SL, Marhazlina M, Nor Azwany Y, Hamid Jan JM. Southeast Asian J Trop Med Public Health. 2011 Sep;42(5):1214–1223.
• Development, validity and reproducibility of a food frequency questionnaire in pregnancy for the Universiti Sains Malaysia Birth Cohort Study. Loy SL, Marhazlina M, Nor Azwany Y, Hamid Jan JM. Malays J Nutr. 2011 Apr;17(1):1–18.
• Development, validity and reliability of a Pregnancy Symptoms Questionnaire. Marhazlina M, Loy SL, Nik Mohamed NZ, Nor Azwany Y, Hamid Jan JM. Malays J Health Sci. 2011 Jan;9(2):15–21.