Dr Tang Yafang

​Clinician Scientist Resident, SingHealth Obstetrics and Gynaecology

Awards

1. 2021: SingHealth Publish! Award
• Poor sleep is associated with higher blood pressure and uterine artery pulsatility index in pregnancy: a prospective cohort study

Research Interests

Dr Tang has been working on epidemiological studies since residency started and published 2 research articles on how sleep changes in pregnancy and its impact on blood pressure and uterine artery doppler

Research Projects

• Defining the Immune Landscape in the Pathogenesis of Endometriosis through singlecell analyses

Potential Future Direction of Research

Dr Tang hopes to embark on immunology-based research using model of endometriosis at this stage and will be working closely with Prof Jerry Chan to develop a research proposal. As endometriosis is a significant clinical condition for both obstetric patients and gynaecological patients, we believe that the research on endometriosis aiming for better understanding of the underlying pathophysiology and searching for new treatment options will benefit our patients greatly.

Publications

1. Tang Y, Zhang J, Dai F, Razali NS, Tagore S, Chern BSM, Tan KH. Sleep quality and BMI in pregnancy– a prospective cohort study. BMC pregnancy and Childbirth. 2022; 22:72 (Impact factor 2.9)
2. Tang Y, Nadarajah R. Challenges in the diagnosis and treatment of extrauterine leiomyoma: case series. IJRCOG. 2022; 11:232
3. Tang Y, Zhang J, Dai F, Razali NS, Tagore S, Chern BSM, Tan KH. Poor sleep is associated with higher blood pressure and uterine artery pulsatility index in pregnancy: a prospective cohort study. BJOG. 2020. doi: 10.1111/1471-0528.16591. (Impact factor 6.531)
4. Tang Y, Aggarwal IM, Chew SH, Lim YK. Primary squamous cell carcinoma of the ovary: A report of two cases and review of the literature. J Gyne Surg. 2016; 32:143.
5. Chua YL, Liong KH, Huang CH, Wong HS, Zhou Q, Ler SS, Tang YF, KemenyDM. Blomia tropicalis-specific TCR transgenic Th2 cells Induce inducible BALT and severe asthma in mice in an IL-4/IL-13 dependent mechanism. J Immunol 2016; 193: 3771. (Impact factor 5.422)
6. Chong SZ, Tan KW, Wong FH, Chua YL, Tang Y, Ng LG, Angeli V, Kemeny DM. CD8 T cells regulate allergic contact dermatitis by modulating CCR2-dependent TNF/iNOS-expressing Ly6C+ CD11b+ monocytic cells. J Invest Dermatol. 2014; 134:666. (Impact factor 7.143)
7. Zhou Q, Ho AW, Schlitzer A, Tang Y, Wong KH, Wong FH, Chua YL, Angeli V, Mortellaro A, Ginhoux F, Kemeny DM. GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis. J Immunol. 2014; 193:496. (Impact factor 5.422)
8. Ge MQ, Ho AW, Tang Y, Wong KH, Chua BY, Gasser S, Kemeny DM. NK cells regulate CD8+ T cell priming and dendritic cell migration during influenza A infection by IFN-γ and perforin-dependent mechanisms. J Immunol. 2012; 189:2099. (Impact factor 5.422)
9. Tang Y, Guan SP, Chua BY, Zhou Q, Ho AW, Wong KH, Wong KL, Wong WS, Kemeny DM. Antigen-specific effector CD8 T cells regulate allergic responses via IFN-r secretion and dendritic cell function. J Allergy Clin Immunol. 2012; 129:1611. (Impact factor 14.110)
10. Wu YJ, Tang YF, Xiao ZC, Bao ZM, He BP. NG2 cells response to axonal alteration in the spinal cord white matter in mice with genetic disruption of neurofilament light subunit expression. Mol Neurodegener. 2008; 3: 18. (Impact factor 9.599)