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KK Women’s and Children’s Hospital (KKH) has established the new Children’s Blood and Cancer Centre (CBCC) to advance research, education and complex care for blood and cancer disorders in babies and children.
Launched in February 2022, the CBCC is one of the most comprehensive paediatric blood and cancer centres in Southeast Asia, focusing on basic science and translational research in childhood cancers, and clinical research in paediatric blood and cancer disorders.
"Research is key in improving outcomes in childhood blood and cancer disorders. As these conditions are rare, with the majority of them having unknown causes, multi-centre and international collaborations are important to advance cures and improve our young patients’ health outcomes."
- Prof Leung Wing Hang, Director, CBCC and Visiting Consultant, Haematology/Oncology Service, KKH
“Cancers in children can be broadly classified as blood cancers, brain tumours and solid tumours. Building on decades of cancer research at KKH, the CBCC will bring us a step closer towards enabling every patient to receive holistic, individualised and targeted treatment,” shares Dr Soh Shui Yen, Head and Senior Consultant, Haematology/Oncology Service, KKH.
The CBCC is led by a multidisciplinary team of paediatric oncology specialists in the fields of:
The centre provides holistic care for paediatric oncology patients diagnosed with:
The CBCC uses the latest treatment protocols of international childhood tumour study groups such as for liver and kidney tumours, and is the only participating site in Southeast Asia to do so. It also provides pathology and molecular pathology consultations for challenging and rare childhood cancers in the region
Transplantation
Beyond clinical treatment, the CBCC houses the Blood and Marrow Transplantation and Cellular Therapy (BMTCT) programme, which has been providing bone and marrow transplantation for children with malignant and non-malignant conditions since 1998.
The availability of advanced donor graft manipulation techniques and supportive care further increases the potential for more eligible donors and cures for patients.
Advanced therapies
Since 2020, the BMTCT programme offers chimeric antigen receptor (CAR) T-cell therapy for patients with relapsed refractory haematologic malignancies, with two approved clinical trials recruiting eligible patients. Rapid advances in the cellular therapy field will enable CAR T-cell therapy to be a safer and more cost-effective treatment, and benefit more patients with different types of cancer.
The KKH Childhood Cancer Survivorship Programme also provides holistic follow-up and care for childhood cancer survivors, and collects longitudinal health data to inform care and support.
Any patient with a history of childhood cancer or cancer/transplant treatment during childhood can be referred to the programme.
General practitioners can refer paediatric patients to:
Director Prof Leung Wing Hang Visiting Consultant, Haematology/Oncology Service
Manager Ms Angeline Lim Asst Manager, Haematology/Oncology Service
Committee Chair Dr Soh Shui Yen Head & Senior Consultant, Haematology/Oncology Service
Benign Haematology Lead Clin Assoc Prof Joyce Lam Senior Consultant, Haematology/Oncology Service; Deputy Head, Department of Pathology and Laboratory Medicine
Malignant Haematology Lead Dr Rajat Bhattacharyya Senior Consultant, Haematology/Oncology Service
Blood and Marrow Transplant and Cellular Therapy Lead Dr Michaela Seng Senior Consultant, Haematology/Oncology Service
Brain and Solid Tumours Lead Dr Amos Loh Senior Consultant, Department of Paediatric Surgery
Survivorship and Late Effects Lead Clin Assoc Prof Tan Ah Moy Senior Consultant, Haematology/Oncology Service
Psychosocial, Preventive, Palliative and Supportive Care Leads Clin Assoc Prof Chan Mei Yoke Senior Consultant, Haematology/Oncology Service Dr Lois Teo Head & Senior Principal Psychologist, Psychology Service
Molecular and Histopathology Lead Clin Assoc Prof Kenneth Chang Head & Senior Consultant, Department of Pathology and Laboratory Medicine
Data Science, Registry and Clinical Trial Management Ms Germaine Liew Senior Clinical Research Coordinator
GMP and Quality Management Lead Dr Chu Pak Yan Senior Principal Medical Lab Scientist, Department of Pathology and Laboratory Medicine
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