Dr Aw Sze Jet

MBBS, MMed (Pathology), FRCPath, FRCPA

Associate Consultant

Clinical Appointments

Associate Consultant Department of Pathology and Laboratory Medicine KK Women's and Children's Hospital

Profile

Dr Aw Sze Jet is an associate consultant practicing anatomical pathology in the Department of Pathology and Laboratory Medicine at KK Women’s and Children’s Hospital in Singapore. During his anatomical pathology training under the Singhealth cluster, he was appointed resident-lead and was also recognized as an ‘Associate in Education’.

Education

FRCPA 2023
FRCPath 2023
MMED Pathology Western Sydney University (Australia) 2022
MBBS National University of Singapore 2015

Professional Appointments and Committee Memberships

Associate Consultant, Department of Pathology and Laboratory Medicine, KK Women’s and Children’s Hospital 2023 - Present

Awards

Best Poster Award (Research), CGH-EH Alliance Scientific Meeting, 2013
Best Platform Presentation (Medical Student), SingHealth Pathology Research Day, 2014
1st Runner Up for Platform Presentation (Residents), SingHealth Pathology Research Day, 2016
Best Platform Presentation (Residents), SingHealth Pathology Research Day, 2018
Best Poster Presentation (Residents), SingHealth Pathology Research Day, 2019
1st Runner Up for Platform Presentation (Residents), SingHealth Pathology Research Day, 2019
Best Poster Presentation (Residents), SingHealth Pathology Research Day, 2020
Best Platform Presentation (Residents), SingHealth Pathology Research Day, 2021
Associate In Education, SingHealth, 2023

Research Interests

Pediatric brain tumours

Publications and Research Trials

CNS embryonal tumour with concomitant novel BRD4::CTRC1 fusion and BCOR internal tandem duplication – evidence for synergism and non-mutually exclusive alterations in CNS embryonal tumours. Aw, S., Tan, E., Low, S. et al. Acta Neuropathol Commun (2024) 12, 33 (2024). https://doi.org/10.1186/s40478-024-01741-y
Targeting mutant dicer tumorigenesis in pleuropulmonary blastoma via inhibition of RNA polymerase I. Wong, M. R. E., Lim, K. H., Hee, E. X. Y., Chen, H., Kuick, C. H., Aw, S. J., Chang, K. T. E., Syed Sulaiman, N., Low, S. Y., Hartono, S., Tran, A. N. T., Ahamed, S. H., Lam, C. M. J., Soh, S. Y., Hannan, K. M., Hannan, R. D., Coupland, L. A., & Loh, A. H. P. Translational research : the journal of laboratory and clinical medicine (2023), 258, 60–71.
Paediatric BCOR- associated sarcomas with a novel long spliced internal tandem duplication of BCOR exon 15. Goh, Jian & Kuick, Chik & Sugiura, Masahiro & Aw, Sze & Zhao, Manli & Tang, Hongfeng & Gunaratne, Sandini & Zhu, Fucun & Cai, Lin & Teh, Tean & Thorner, Paul & Chang, Kenneth Tou-En. The Journal of Pathology Clinical Research. (2022) 8. 10.1002/cjp2.287.
Clinicopathological characteristics of NTRK-rearranged mesenchymal tumors in childhood. Yin, M & Ma, J & He, Q & Shen, P & Chen, J & Jin, X & Zhang, Z & Kuick, C & Chen, H & Ng, E & Aw, S & Chang, Kenneth Tou-En. Zhonghua bing li xue za zhi Chinese journal of pathology (2020). 49. 675-680. 10.3760/cma.j.cn112151-20200214-00095.
Congenital mesoblastic nephroma is characterised by kinase mutations including EGFR internal tandem duplications, the ETV6 – NTRK3 fusion, and the rare KLHL7 – BRAF fusion. Zhao, M., Yin, M., Kuick, C., Chen, H., Aw, S., Merchant, K., Ng, E., Gunaratne, S., Loh, A., Gu, W., Tang, H. and Chang, K., Histopathology (2020). 77(4), pp.611-621.
Clear Cell Sarcoma of the Kidney. Aw, S. and Chang, K. Archives of Pathology & Laboratory Medicine, (2019) 143(8), pp.1022-1026.
Cord Knots and Pseudo-Knots. In: Khong T., Mooney E., Nikkels P., Morgan T., Gordijn S. (eds), Chang K.T.E., Aw S.J. Pathology of the Placenta (2019). Springer, Cham
Umbilical Cord Tumours. In: Khong T., Mooney E., Nikkels P., Morgan T., Gordijn S. (eds), Chang K.T.E., Aw S.J. Pathology of the Placenta (2019). Springer, Cham
Umbilical Cord Insertion Abnormalities. In: Khong T., Mooney E., Nikkels P., Morgan T., Gordijn S. (eds) Chang K.T.E., Aw S.J. Pathology of the Placenta (2019). Springer, Cham
Clear cell sarcomas of the kidney are characterised by BCOR gene abnormalities, including exon 15 internal tandem duplications and BCOR-CCNB3 gene fusion. Wong, M., Ng, C., Kuick, C., Aw, S., Rajasegaran, V., Lim, J., Sudhanshi, J., Loh, E., Yin, M., Ma, J., Zhang, Z., Iyer, P., Loh, A., Lian, D., Wang, S., Goh, S., Lim, T., Lim, A., Ng, T., Goytain, A., Loh, A., Tan, P., Teh, B. and Chang, K. Histopathology, (2017) 72(2), pp.320-329.
A randomised control trial to compare retention rates of two cardiopulmonary resuscitation instruction methods in the novice. Lim, S., Aw, S., Cheong, M., Chew, J., Ler, A., Yong, L., Chan, Y., Win, M. and Suppiah, N. Resuscitation, (2016) 103, pp.82-87.
Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney. Aw, S., Kuick, C., Yong, M., Lian, D., Wang, S., Loh, A., Ling, S., Peh, G., Soh, S., Loh, A., Tan, P. and En Chang, K. Pediatric and Developmental Pathology (2015) 18(4), pp.297-304.
Sperm entry is sufficient to trigger division of the central cell, but the paternal genome is required for endosperm development in Arabidopsis. Aw, S., Hamamura, Y., Chen, Z., Schnittger, A. and Berger, F. Development (2010) 137(16), pp.2683-2690