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Dr Wong Damon Wing Kee

Dr Wong Damon Wing Kee


Academic Appointments

  • Assistant Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


​Dr Damon Wong is a Junior Principal Investigator in the Ocular Imaging Department at the Singapore Eye Research Institute, and holds a joint appointment as an Assistant Professor with SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme (EYE ACP). He also serves as an Adjunct Scientist at the Institute of Molecular and Cell Biology in Basel, Switzerland.

Dr Wong has been generally interested in exploring the use of computer vision, data science and artificial intelligence-driven techniques in healthcare with a focus in ophthalmology. He has been actively involved in developing approaches to better detect image-based biomarkers in eye diseases such as glaucoma and age-related macular degeneration. He has also explored the use of eye-tracking for visual function analysis and rehabilitation. Beyond ophthalmology, he has also worked with medical images in the fields of dermatology, cardiology, and chronic wound care.

Currently, his research revolves around the use of structural and vascular imaging for visual function modelling in neurodegenerative conditions. He is also particularly interested in the application of artificial intelligence-driven techniques for the modelling and characterisation of vision-threatening conditions from ophthalmic images.


  • PhD (2007)
  • BEng (2003)

Professional Appointments and Committee Memberships

  • Adjunct Scientist, Institute of Molecular and Cell Biology in Basel, Switzerland (2020 - present)


  • IES Prestigious Engineering Achievement Award (2015)
  • IES Prestigious Engineering Achievement Award (2013)
  • A*STAR Graduate Scholarship (2003)

Research Interests

  • Structural, vascular and function associations in glaucoma and neurodegenerative conditions
  • Generative artificial intelligence in ophthalmology
  • Ophthalmic image analysis

Publications and Research Trials

  1. Kumar AJS, Chong RS, Crowston JG, Chua J, Bujor I, Husain R, Vithana EN, Girard MJA, Ting DSW, Cheng CY, Aung T, Popa-Cherecheanu A, Schmetterer L, Wong D. Evaluation of Generative Adversarial Networks for High-Resolution Synthetic Image Generation of Circumpapillary Optical Coherence Tomography Images for Glaucoma. JAMA Ophthalmol. 2022. 140(10): p. 974-981. JIF 8.253
  2. Wong D, Chua J, Bujor I, Chong RS, Nongpiur ME, Vithana EN, Husain R, Aung T, Popa-Cherecheanu, A, Schmetterer L. Comparison of Machine Learning Approaches for Structure–function Modeling in Glaucoma. Ann N Y Acad Sci. 2022. 1515(1): p. 237-248. JIF 5.691
  3. Yow AP, Tan B, Chua J, Husain R, Schmetterer L, Wong D. Segregation of Neuronal-vascular Components in a Retinal Nerve Fiber Layer for Thickness Measurement using OCT and OCT Angiography. Biomed Opt Express. 2021. 12(6): p. 3228-3240. JIF 3.562
  4. Kallab M, Hommer N, Schlatter A, Chua J, Tan B, Schmidl D, Hirn C, Findl O, Schmetterer L, Garhöfer G, Wong D. Combining Vascular and Nerve Fiber Layer Thickness Measurements to Model Glaucomatous Focal Visual Field Loss. Ann N Y Acad Sci. 2022. 1511(1): p. 133-141. JIF 5.691
  5. Cahyo DA, Yow AP, Saw SM, Ang M, Girard M, Schmetterer L, Wong D. Multi-task Learning Approach for Volumetric Segmentation and Reconstruction in 3D OCT Images. Biomedical Optics Express. 2021. 12(12): p. 7348-7360. JIF 3.562
  6. Wong D, Chua J, Tan B, Yao X, Chong R, Sng CC, Husain R, Aung T, Garway-Heath D, Schmetterer L. Combining OCT and OCTA for Focal Structure–Function Modeling in Early Primary Open-Angle Glaucoma. Invest Ophthalmol Vis Sci. 2021. 62(15): p. 8-8. JIF 4.925
  7. Wong D, Chua J, Baskaran M, Tan B, Yao X, Chan S, Tham YC, Chong R, Aung T, Lamoureux, EL. Factors Affecting the Diagnostic Performance of Circumpapillary Retinal Nerve Fibre Layer Measurement in Glaucoma. Br J Ophthalmol. 2021. 105(3): p. 397-402. JIF 5.907
  8. Calzetti G, Mursch-Edlmayr AS, Bata AM, Ungaro N, Mora P, Chua J, Schmidl D, Bolz M, Garhöfer G, Gandolfi S, Schmetterer L, Wong D. Measuring Optic Nerve Head Perfusion to Monitor Glaucoma: A Study on Structure-function Relationships using Laser Speckle Flowgraphy. Acta Ophthalmol. 2022. 100(1): p. e181-e191. JIF 3.988
  9. Wong D, Chua J, Lin E, Tan B, Yao X, Chong R, Sng C, Lau A, Husain R, Aung T, Schmetterer L. Focal Structure–Function Relationships in Primary Open-Angle Glaucoma Using OCT and OCT-A Measurements. Invest Ophthalmol Vis Sci. 2020. 61(14): p. 33-33. JIF 4.925
  10. Yow AP, Lee WZ, Wong DWK, Tey HL, Subsurface Detection of Hair Follicles in Alopecia Areata using Optical Coherence Tomography. Skin Res Technol. 2022. JIF 2.24
  11. Chua J, Le TT, Sim YC, Chye HY, Tan B, Yao X, Wong D, Ang BW, Toh DF, Lim H. Relationship of Quantitative Retinal Capillary Network and Myocardial Remodeling in Systemic Hypertension. J Am Heart Assoc. 2022. 11(6): p. e024226. JIF 6.106
  12. Chua J, Li C, Ho LKH, Wong D, Tan B, Yao X, Gan A, Schwarzhans F, Garhöfer G, Sng CC. A Multi-regression Framework to Improve Diagnostic Ability of optical Coherence Tomography Retinal Biomarkers to Discriminate Mild Cognitive Impairment and Alzheimer’s Disease. Alzheimers Res Ther. 2022. 14(1): p. 1-11. JIF 9.037
  13. Chua J, Bostan M, Li C, Sim YC, Bujor I, Wong D, Tan B, Yao X, Schwarzhans F, Garhöfer G. A Multi-Regression Approach to Improve Optical Coherence Tomography Diagnostic Accuracy in Multiple Sclerosis Patients Without Previous Optic Neuritis. NeuroImage Clin. 2022. 34: p. 103010. JIF 4.891
  14. Kadziauskienė A, Chua J, Baskaran M, Yow AP, Tan B, Sng C, Ašoklis R, Lesinskas E, Crowston J, Schmetterer L, Wong DWK. Association Between Structure-function Characteristics and Visual Field Outcomes in Glaucoma Subjects with Intraocular Pressure Reduction after Trabeculectomy. J Glaucoma. 2020. 29(8): p. 648-655. JIF 2.503
  15. Fu H, Xu Y, Lin S, Wong DWK, Baskaran M, Mahesh M, Aung T, Liu J. Angle-closure Detection in Anterior Segment OCT Based on Multilevel Deep Network. IEEE Trans Cybern. 2019. 50(7): p. 3358-3366. JIF 19.118
  16. Yan Q, Xu M, Wong DWK, Taruya A, Tanaka A, Liu J, Wong P, Cheng J. Automatic Fibroatheroma Identification in Intravascular Optical Coherence Tomography Volumes. J Ambient Intell Humaniz Comput. 2019: p. 1-7. JIF 3.662
  17. Cheng J, Tao D, Quan Y, Wong DWK, Cheung GCM, Akiba M, Liu J. Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction. IEEE Trans Med Imaging. 2016. 35(10): p. 2270-2279. JIF 11.037
  18. Srivastava R, Yow AP, Cheng J, Wong DW, Tey HL. Three-dimensional Graph-based Skin Layer Segmentation in Optical Coherence Tomography Images for Roughness Estimation. Biomed Opt Express. 2018. 9(8): p. 3590-3606. JIF 3.562
  19. Cheng J, Liu J, Xu Y, Yin F, Wong DWK, Tan NM, Tao D, Cheng CY, Aung T, Wong TY. Superpixel Classification based Optic Disc and Optic Cup Segmentation for Glaucoma Screening. IEEE Trans Med Imaging. 2013. 32(6): p. 1019-1032. JIF 11.037
  20. Trucco E, Ruggeri A, Karnowski T, Giancardo L, Chaum E, Hubschman JP, Al-Diri B, Cheung CY, Wong, D, Abràmoff M, Lim G, Kumar D, Burlina P, Bressler NM, Jelinek HF, Meriaudeau F, Quellec G, Macgillivray T, Dhillon B. Validating Retinal Fundus Image Analysis Algorithms: Issues and a Proposal. Invest Ophthalmol Vis Sci. 2013. 54(5): p. 3546-3559. JIF 4.925

Research Trials

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