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Klinefelter syndrome (KS) is a chromosomal condition that describes boys and men with common features, physical traits and medical conditions that are caused by the presence of an extra X chromosome (i.e., XXY).
Both males and females generally have 46 chromosomes. In females, this includes two X chromosomes, while males have one X and one Y chromosome.
It is estimated that one in 500 to 1,000 males are born with KS.