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Treatment depends on the degree of acute inflammation and chronic scarring, but usually involves medications to stop the immune system from attacking kidney cells Common medications used include prednisolone, cyclophosphamide, mycophenolate mofetil or mycophenolate sodium and hydroxychloroquine.
Patients with high blood pressure or swelling may be given medications to lower blood pressure or remove excessive fluid. They will also be advised to eat less salt.
Treatment usually helps to control kidney inflammation However, it is essential for patients to visit their doctor regularly, as the disease tends to “flare up” in up to two thirds of patients and up to 10 of patients may not respond to therapy and develop end stage renal disease. These patients will need dialysis or a kidney transplant within five years.