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Raloxifene belongs to a group of non-hormonal medicines called Selective Estrogen Receptor Modulators (SERMs). Raloxifene is used for the treatment and prevention of osteoporosis in postmenopausal women by mimicking some of the helpful effects of estrogen after menopause.
Raloxifene may cause the following side effects:
Hot flushes (Wear loose fitting clothes or go to areas with air-con)
Flu-like symptoms
Leg cramps
Swelling of hands, feet and legs
Nausea and vomiting (You may take it with or after meals to minimize stomach upset)
Headache (You may take painkillers e.g. paracetamol for mild headaches)
Mild breast symptoms such as pain, enlargement and tenderness
Generally, these side effects tend to occur at the beginning of treatment and will improve with time. Inform your doctor if the side effects above become severe or persistent.
Report to your doctor immediately if you experience any of the following:
Symptoms of blood clot in veins:
Any unusual sudden cough
Severe pain in the chest which may reach the left arm
Change in your speech, including slurring of words
Change in your senses of hearing, smell or taste
Breathlessness or difficulty in breathing
Unusual, severe or long lasting headache or worsening of migraine
Dizziness or fainting
Severe pain in your abdomen
Severe pain, numbness in legs or swelling in either of your legs.
Weakness or numbness in any part of your body
Stop the medication immediately and seek medical attention if you experience any severe allergic reactions like skin rash (with or without blisters, mouth ulcers, fever and itching), swelling of the eyes and lips or difficulty breathing.
Raloxifene is usually taken once a day. Your doctor may also prescribe it together with calcium and vitamin D supplements.
Raloxifene may be administered with or without food.
Take the missed dose as soon as you remember. If you remember a missed dose at the time of your next dose, omit the missed dose and take only your regularly scheduled dose. Do not take a double dose to make up for the missed one.
Blood clots can sometimes form in your legs during air travel if you are immobile for long periods of time (usually in flights that are 8 – 10 hours long) and often sitting in cramped spaces with little leg room. To avoid this:
Move around the airplane every few hours to stretch your legs
Store carry-on baggage in a place that will allow enough leg room
Try not to cross legs while sitting down
Wear loose-fitting clothes that do not restrict blood flow and make it easier to move around
Wear compression stockings
Updated on Monday, October 31, 2022
This article is contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup