Clin Prof Yeo Khung Keong

MBBS (S’pore), FAMS

Chief Executive Officer ＆ Senior Consultant

Specialty: Cardiology

Sub-specialties: Interventional Cardiology, Structural Heart Disease, Vascular Medicine, Peripheral Arterial Interventions

Conditions Treated by this Doctor:
Broken Heart Syndrome, Cardiac Catheterisation, Cardiovascular Disease, Coronary Angiography, Coronary Angioplasty, Coronary Artery Disease, Coronary Atherectomy, Coronary Stent Implantation, Heart Attack (Myocardial Infarction), Mitral Valve Disease, Mitral Valve Regurgitation, Transcatheter Mitral Valve Repair – MitraClip and PASCAL, TriClip™, Tricuspid Valve Regurgitation, TricValve®.

Clinical Appointments

Chief Executive Officer ＆ Senior Consultant Department of Cardiology National Heart Centre Singapore

Academic Appointments

Academic Chair SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme

Profile

Clinical Professor Yeo Khung Keong is the Chief Executive Officer and a Senior Consultant with the Department of Cardiology at the National Heart Centre Singapore (NHCS). He is also the Academic Chair of the SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme and Deputy Co-Chair and Lead (Emerging Technologies and Data) at the SingHealth Duke-NUS Academic Medicine Innovation Institute. Clin Prof Yeo leads the MitraClip programme at NHCS, and his clinical interests are in interventional cardiology, structural heart disease, vascular medicine and peripheral arterial interventions.

Clin Prof Yeo is a Clinical Professor with Duke-NUS Medical School and is the Scientific Lead for the Clinical Sciences and Database Core at the National Heart Research Institute Singapore (NHRIS). In research work, he is the Principal Investigator of the SingCLOUD and SingHEART studies. He also held the role of Deputy Group Chief Medical Informatics Officer (Research), SingHealth from 2018 to 2024.

Clin Prof Yeo is a Fellow of the American College of Cardiology (FACC), the European Society of Cardiology (FESC), the Academy of Medicine, Singapore (FAMS), the American Heart Association (FAHA), the Asian Pacific Society of Cardiology (FAPSC) and the Japanese Circulation Society (FJCS).

He is the Past-Chair of the Scientific Advisory Board for the Asian Pacific Society of Cardiology (APSC), Chapter of Cardiologists, Academy of Medicine, Singapore and the Founding Editor-in-Chief of the Journal of the APSC. Clin Prof Yeo is a board member for the College of Physicians, Academy of Medicine Singapore, and council member of the Singapore Cardiac Society.

Education

Executive Master of Business Administration, France/ Singapore/ Abu Dhabi, INSEAD, 2018
SMU-SingHealth Graduate Diploma in Healthcare Management and Leadership (GDHM), Singapore Management University, 2015
The American Board of Vascular Medicine (Vascular Medicine and Endovascular, UC Davis Medical Center, Sacramento, CA, USA, 2010
The American Board of Internal Medicine (Interventional Cardiology), UC Davis Medical Center, Sacramento, CA, USA, 2009
The American Board of Internal Medicine (Cardiovascular Medicine), UC Davis Medical Center, Sacramento, CA, USA, 2008
The American Board of Internal Medicine (Internal Medicine), UC Davis Medical Center, Sacramento, CA, USA, 2005
Bachelor of Medicine and Bachelor of Surgery (M.B.B.S), National University of Singapore, 1997

Professional Appointments and Committee Memberships

Chief Executive Officer, NHCS, 1 June 2023 to Present
Academic Chair of the SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme, June 2023 to Present
Deputy Co-Chair & Lead (Emerging Technologies and Data), SingHealth Duke-NUS Academic Medicine Innovation Institute
Deputy Chief Executive Officer (Data Science and Innovation), NHCS, April 2022 to 31 May 2023
Deputy Medical Director (Data Science and Innovation), NHCS, January 2022 to March 2022
Senior Consultant, Department of Cardiology, NHCS, 2013 to Present
Deputy Group Chief Medical Informatics Officer (Research), SingHealth, October 2018 to Present
Research EXCO, SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme, to May 2023
Vice Chair, Education and Training, SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme, April 2016 to March 2021
Chair, Chapter of Cardiologists, Academy of Medicine, May 2017 to 2021
Chair, Scientific Advisory Board, Asian Pacific Society of Cardiology, 2015 tp Present
Fellow, Academy of Medicine Singapore, 2013
Fellow, American College of Cardiology, 2012
Fellow, Society for Cardiovascular Angiography and Interventions, 2012
Member, American Heart Association, 2012
Ordinary Member, Singapore Cardiac Society, 2012
Full membership, Academic Medicine Education Institute, 10/2012

Awards

Singapore Health Quality Service Awards, Silver Award, 2023
National Day Awards, The Public Administration Medal (Bronze), 2022
SingHealth RiSE Awards 2020 – Outstanding Faculty Award
SingHealth Excellence Awards 2016 – Outstanding Educator
Service Quality Silver Award, SingHealth, 2013
Service Quality Bronze Award, NHCS, 2013
Winner, 2008 Cardiovascular Research Award, Division of Cardiovascular Medicine, University of California, Davis, Sacramento, California
Best resident, Nephrology, 2005, Internal Medicine Residency Program University of Hawaii, Honolulu, Hawaii
Best resident, Cardiology, 2005, Internal Medicine Residency Program University of Hawaii, Honolulu, Hawaii
Best Internal Medicine Resident 2005, Queens Medical Center, Honolulu, Hawaii

Research Interests

Percutaneous mitral valve interventions
Outcomes in percutaneous coronary interventions, including health services research
Database, Registry, Data Science and Big Data research

Publications and Research Trials

Chetna Malhotra, Isha Chaudhry, Yeo Khung Keong, Kheng Leng David Sim. Multifactorial risk factors for hospital readmissions among patients with symptoms of advanced heart failure. ESC Heart Fail.2024 Jan 25. doi: 10.1002/ehf2.14670
Mun Yee Tham, Cheng Leng Chan, Dorothy Toh, Jalene Poh, Adena Lim, Sally Soh, Li Fung Peck, Belinda Foo, Amelia Ng, Patricia Ng, Pei San Ang, Sreemanee Dorajoo, Desmond Teo, Toon Wei Lim, Yean Teng Lim, Jonathan Choo, Zee Pin Ding, Khung Keong Yeo, Jonathan Yap, Hui Xing Tan. An updated analysis on myocarditis and pericarditis cases reported following mRNA SARS-CoV-2 vaccination in Singapore. Singapore Med J. 2024 Feb 16. doi: 10.4103/singaporemedj.SMJ-2023-089. Online ahead of print.
Daniel Moynihan, Sean Monaco, Teck Wah Ting, Kaavya Narasimhalu, Jenny Hsieh, Sylvia Kam, Jiin Ying Lim, Weng Khong Lim, Sonia Davila, Yasmin Bylstra, Iswaree Devi Balakrishnan, Mark Heng, Elian Chia, Khung Keong Yeo, Bee Keow Goh, Ritu Gupta, Tele Tan, Gareth Baynam, Saumya Shekhar Jamuar. Cluster analysis and visualisation of electronic health records data to identify undiagnosed patients with rare genetic diseases. Sci Rep. 2024 Mar 1;14(1):5056. doi: 10.1038/s41598-024-55424-8
Jack Wei Chieh Tan, Tee Joo Yeo, Doreen SY Tan, Terrance Siang Jin Chua, Khung Keong Yeo, Natalie Si Ya Koh, Tavintharan Subramaniam, Yew Seng Kwan, Michael Chun Leng Lim, Lip Ping Low, Huay Cheem Tan. Strategies to prevent cardiovascular disease in Singapore: A call to action from Singapore Heart Foundation, Singapore Cardiac Society and Chapter of Cardiologists of the Academy of Medicine, Singapore. Annals. Review ArticleVol. 53 No. 1, 23–33, https://doi.org/10.47102/annals-acadmedsg.2023141, 30 January 2024
Paul Jie Wen Tern, Khung Keong Yeo, Jack Wei Chieh Tan, Chee Tang Chin, Ru San Tan, Jonathan Yap. Role of anticoagulation in non-ST-elevation myocardial infarction: a contemporary narrative review. Expert Rev Cardiovasc Ther.2024 May 14:1-13. doi: 10.1080/14779072.2024.2354243.
Heerajnarain Bulluck, Jun Hua Chong, Jennifer Bryant, Annitha Annathurai, Ping Chai, Mervyn Chan, Ashish Chawla, Chee Yang Chin, Yiu-Cho Chung, Fei Gao, Hee Hwa Ho, Andrew Fu Wah Ho, John Hoe, Syed Saqib Imran, Chi-Hang Lee, Benji Lim, Soo Teik Lim, Swee Han Lim, Boon Wah Liew, Patrick Lim Zhan Yun, Marcus Eng Hock Ong, Valeria Paradies, Xuan Ming Pung, Julian Cheong Kiat Tay, Lynette Teo, Boon Ping Ting, Aaron Wong, Evelyn Wong, Timothy Watson, Mark Y Chan, Yeo Khung Keong, Jack W C Tan, Derek J Hausenloy; PITRI Investigators. Effect of Cangrelor on Infarct Size in ST-Segment Elevation Myocardial Infarction Treated By Primary Percutaneous Coronary Intervention: A Randomized Controlled Trial (The PITRI Trial). Circulation. 2024 May 14. doi: 10.1161/CIRCULATIONAHA.124.068938
Yang LWY, Ng WY, Lei X, Tan SCY, Wang Z, Yan M, Pargi MK, Zhang X, Lim JS, Gunasekeran DV, Tan FCP, Lee CE, Yeo KK, Tan HK, Ho HSS, Tan BWB, Wong TY, Kwek KYC, Goh RSM, Liu Y, Ting DSW. Development and testing of a multi-lingual Natural Language Processing-based deep learning system in 10 languages for COVID-19 pandemic crisis: A multi-center study. Front Public Health. 2023;11:1063466. doi: 10.3389/fpubh.2023.1063466
Wong MYZ, Yap JJL, Chih HJ, Yan BPY, Fong AYY, Beltrame JF, Wijaya IP, Nguyen HTT, Brennan AL, Reid CM, Yeo KK. Regional differences in percutaneous coronary intervention outcomes in STEMI patients with diabetes: The Asia-Pacific evaluation of cardiovascular therapies (ASPECT) collaboration. Int J Cardiol. 2023;371:84-91. doi: 10.1016/j.ijcard.2022.10.001
Mayank Dalakoti, Roger Foo; RESET Consortium, Yeo Khung Keong. Redirecting immune, lipid, and metabolic drivers of early cardiovascular disease: the RESET cohort study and randomized trial. Eur Heart J. 2023 Oct 14;44(39):3939-3941. doi: 10.1093/eurheartj/ehad543
Tern PJW, Vaswani A, Yeo KK. Identifying and Solving Gaps in Pre- and In-Hospital Acute Myocardial Infarction Care in Asia-Pacific Countries. Korean Circ J. 2023;53:594-605. doi: 10.4070/kcj.2023.0169 • Shih CC, Chen J, Lee AS, Bertin N, Hebrard M, Khor CC, Li Z, Juan Tan JH, Meah WY, Peh SQ, Mok SQ, Sim KS, Liu J, Wang L, Wong E, Li J, Tin A, Cheng CY, Heng CK, Yuan JM, Koh WP, Saw SM, Friedlander Y, Sim X, Chai JF, Chong YS, Davila S, Goh LL, Lee ES, Wong TY, Karnani N, Leong KP, Yeo KK, Chambers JC, Lim SC, Goh RSM, Tan P, Dorajoo R. A five-safes approach to a secure and scalable genomics data repository. iScience. 2023;26:106546. doi: 10.1016/j.isci.2023.106546
Seah JYH, Yao J, Hong Y, Lim CGY, Sabanayagam C, Nusinovici S, Gardner DS, Loh M, Muller-Riemenschneider F, Tan CS, Yeo KK, Wong TY, Cheng CY, Ma S, Tai ES, Chambers JC, van Dam RM, Sim X. Risk prediction models for type 2 diabetes using either fasting plasma glucose or HbA1c in Chinese, Malay, and Indians: Results from three multi-ethnic Singapore cohorts. Diabetes Res Clin Pract. 2023;203:110878. doi: 10.1016/j.diabres.2023.110878
Reid CM, Chih H, Duffy SJ, Brennan AL, Ajani AE, Beltrame J, Tavella R, Yan BP, Dinh D, Chin CT, Do LD, Nguyen QN, Nguyen HTT, Wijaya IP, Yamin M, Rusdi L, Alwi I, Sim KH, Yip Fong AY, Wan Ahmad WA, Yeo KK, Investigators A. Harmonising Individual Patient Level Cardiac Registry Data Across the Asia Pacific Region-A Feasibility Study of In-Hospital Outcomes of STEMI Patients From the Asia Pacific Evaluation of Cardiovascular Therapies (ASPECT) Network. Heart Lung Circ. 2023;32:166-174. doi: 10.1016/j.hlc.2022.08.012
Ozdemir S, Lee JJ, Yeo KK, Sim KLD, Finkelstein EA, Malhotra C. A Prospective Cohort Study of Medical Decision-Making Roles and Their Associations with Patient Characteristics and Patient-Reported Outcomes among Patients with Heart Failure. Med Decis Making. 2023;43:863-874. doi: 10.1177/0272989X231201609
Man REK, Ho AXY, Lee EPX, Fenwick EKD, Aravindhan A, Ho KC, Wei Tan GS, Wei Ting DS, Wong TY, Yeo KK, Goh SY, Gupta P, Lamoureux EL. Awareness and attitudes of elderly Southeast Asian adults towards telehealth during the COVID-19 pandemic: a qualitative study. Singapore Med J. 2023. doi: 10.4103/singaporemedj.SMJ-2022-117
Lee SYA, Loh PH, Lau YH, Jiang Y, Liew BW, Lim PZY, Rastogi S, Tan WCJ, Ho HH, Yeo KK. Impact of COVID-19 pandemic early response measures on myocardial infarctions and acute cardiac care in Singapore. Int J Qual Health Care. 2023;35. doi: 10.1093/intqhc/mzad023
Koh SJQ, Yap J, Jiang Y, Sng GGR, Low YH, Lau YH, Sin YKK, Yeo KK. Clinical outcomes in end stage renal disease on dialysis and severe coronary artery disease: A real-world study. Int J Cardiol. 2023. doi: 10.1016/j.ijcard.2023.02.029
Gorny AW, Yap J, Neo JW, Chow WE, Yeo KK, Tan CS, Muller-Riemenschneider F. Cardiorespiratory fitness, body mass index, cardiovascular disease, and mortality in young men: A cohort study. Front Public Health. 2023;11:1076065. doi: 10.3389/fpubh.2023.1076065
Fong KY, Low CHX, Chan YH, Ho KW, Keh YS, Chin CT, Chin CY, Fam JM, Wong N, Idu M, Wong ASL, Lim ST, Koh TH, Tan JWC, Yeo KK, Yap J. Role of Invasive Strategy for Non-ST-Elevation Myocardial Infarction in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Am J Cardiol. 2023;205:369-378. doi: 10.1016/j.amjcard.2023.07.178
Chew NWS, Chong B, Kuo SM, Jayabaskaran J, Cai M, Zheng H, Goh R, Kong G, Chin YH, Imran SS, Liang M, Lim P, Yong TH, Liew BW, Chia PL, Ho HH, Foo D, Khoo D, Huang Z, Chua T, Tan JWC, Yeo KK, Hausenloy D, Sim HW, Kua J, Chan KH, Loh PH, Lim TW, Low AF, Chai P, Lee CH, Yeo TC, Yip J, Tan HC, Mamas MA, Nicholls SJ, Chan MY. Trends and predictions of metabolic risk factors for acute myocardial infarction: findings from a multiethnic nationwide cohort. Lancet Reg Health West Pac. 2023;37:100803. doi: 10.1016/j.lanwpc.2023.100803
Cai XJ, Tay JCK, Jiang Y, Yeo KK, Wong PEH, Ho KL, Chong DTT, Ti LK, Leong G, Wong K, Ching CK. Non-invasive mid-term electrocardiogram patch monitoring is effective in detecting atrial fibrillation. J Electrocardiol. 2023;81:230-236. doi: 10.1016/j.jelectrocard.2023.09.014
Robert Azzopardi, Stephen J Nicholls, Nitesh Nerlekar, Daniel J Scherer, Chanchal Chandramouli, Carolyn S P Lam 4, Rahul Muthalaly, Sean Tan, Christopher X Wong, Derek P Chew, Sophia Zoungas, Khung Keong Yeo, Adam J Nelson. Asia-Pacific Investigators and Asian Enrollment in Cardiometabolic Trials: Insights From Publications Between 2011 and 2020. JACC Asia. 2023 Jul 4;3(5):724-735. doi: 10.1016/j.jacasi.2023.05.010. eCollection 2023 Oct.
T T Le, J A Bryant, C Y Chin, K K Yeo, J W C Tan, K W Ho, C C W Chin. Association between fractional flow reserve and CMR-derived exercise capacity. European Heart Journal - Cardiovascular Imaging, Volume 24, Issue Supplement_1, June 2023, jead119.430, https://doi.org/10.1093/ehjci/jead119.430
Jonathan Gabriel Sung, Ho Lam, Chui Ka-Lung, Anthony Yiu-Tung Wong, Jonathan Jiunn Liang Yap, Zhen-Vin Lee, Sidney TH Lo, Ajar Kochar, Houng-Bang Liew, Christoph Julian Jensen, Dharmaraj Karthikesan, Jack Wei-Chieh Tan, Ping-Wa Yam, Khung Keong Yeo, Duk-Woo Park, Eric Eeckhout. Use of Mechanical Circulatory Support in Complex High-risk Percutaneous Coronary Intervention: A Review of Current Evidence. Journal of Asian Pacific Society of Cardiology 2023;2:e40
Samuel Ji Quan Koh, Khung Keong Yeo, Jonathan Jiunn-Liang Yap. Leveraging ChatGPT to aid patient education on coronary angiogram. Ann Acad Med Singap. 2023 Jul 28;52(7):374-377. https://doi.org/10.47102/annals-acadmedsg.2023138
Yi Hua Low, Gerald Gui Ren Sng, Samuel Ji Quan Koh, Jonathan Jiunn Liang Yap, Yee How Lau, Danielle Yi Ting Tan Yilin Jiang, Kenny Yoong Kong Sin, Khung Keong Yeo. Reasons for Coronary Artery Bypass Graft Rejection: Patients’ and Surgeons’ Perspective. Journal of Asian Pacific Society of Cardiology 2023;2:e12
Ru Ying Fong, Annie Lee, Fei Gao, Jonathan Jiunn Liang Yap, Khung Keong Yeo. Cardiometabolic Risk Factors and COVID-19 Outcomes in the Asia-Pacific Region: A Systematic Review, Meta-analysis and Meta-regression of 84,011 Patients. Journal of Asian Pacific Society of Cardiology 2023;2:e22. https://doi.org/10.15420/japsc.2022.27
Zhou W, Chan YE, Foo CS, Zhang J, Teo JX, Davila S, Huang W, Yap J, Cook S, Tan P, Chin CW, Yeo KK, Lim WK, Krishnaswamy P. High-Resolution Digital Phenotypes From Consumer Wearables and Their Applications in Machine Learning of Cardiometabolic Risk Markers: Cohort Study. J Med Internet Res. 2022;24:e34669. doi: 10.2196/34669
Yap J, Tham MY, Poh J, Toh D, Chan CL, Lim TW, Lim SL, Chia YW, Lim YT, Choo J, Ding ZP, Foo LL, Kuo S, Lau YH, Lee A, Yeo KK. Pericarditis and myocarditis after COVID-19 mRNA vaccination in a nationwide setting. Ann Acad Med Singap. 2022;51:96-100. doi: 10.47102/annals-acadmedsg.2021425
Wong MYZ, Yap JJL, Chih HJ, Yan BPY, Fong AYY, Beltrame JF, Wijaya IP, Nguyen HTT, Brennan AL, Reid CM, Yeo KK. Regional differences in percutaneous coronary intervention outcomes in STEMI patients with diabetes: The Asia-Pacific evaluation of cardiovascular therapies (ASPECT) collaboration. Int J Cardiol. 2022. doi: 10.1016/j.ijcard.2022.10.001
Wong JJ, Umapathy S, Keh YS, Lau YH, Yap J, Idu M, Chin CY, Fam JM, Liew BW, Chin CT, Wong PEH, Koh TH, Yeo KK. Coronary Intravascular Lithotripsy Versus Rotational Atherectomy in an Asian Population: Clinical Outcomes in Real-World Patients. Korean Circ J. 2022;52:288-300. doi: 10.4070/kcj.2021.0155
Vijayan S, Ho QY, Koh CH, Liew IT, Thangaraju S, Wong N, Keh YS, Ong ZHS, Tan JQ, Yeo KK, Chua TSJ, Kee T. Cardiac evaluation for end-stage kidney disease patients on the transplant waitlist: a single-center cohort study. Korean J Transplant. 2022;36:187-196. doi: 10.4285/kjt.22.0029
Tromp J, Jindal D, Redfern J, Bhatt A, Severin T, Banerjee A, Ge J, Itchhaporia D, Jaarsma T, Lanas F, Lopez-Jimenez F, Mohamed A, Perel P, Perez GE, Pinto F, Vedanthan R, Verstrael A, Yeo KK, Zulfiya K, Prabhakaran D, Lam CSP, Cowie MR. World Heart Federation Roadmap for Digital Health in Cardiology. Glob Heart. 2022;17:61. doi: 10.5334/gh.1141
Reid CM, Chih H, Duffy SJ, Brennan AL, Ajani AE, Beltrame J, Tavella R, Yan BP, Dinh D, Chin CT, Do LD, Nguyen QN, Nguyen HTT, Wijaya IP, Yamin M, Rusdi L, Alwi I, Sim KH, Yip Fong AY, Wan Ahmad WA, Yeo KK, Investigators A. Harmonising Individual Patient Level Cardiac Registry Data Across the Asia Pacific Region-A Feasibility Study of In-Hospital Outcomes of STEMI Patients From the Asia Pacific Evaluation of Cardiovascular Therapies (ASPECT) Network. Heart Lung Circ. 2022. doi: 10.1016/j.hlc.2022.08.012
Ozdemir S, Lee JJ, Malhotra C, Teo I, Yeo KK, Than A, Sim KLD, Finkelstein E. Associations Between Prognostic Awareness, Acceptance of Illness, and Psychological and Spiritual Well-being Among Patients With Heart Failure. J Card Fail. 2022;28:736-743. doi: 10.1016/j.cardfail.2021.08.026
Loh X, Sun L, Allen JC, Goh HJ, Kong SC, Huang W, Ding C, Bosco N, Egli L, Actis-Goretta L, Magkos F, Arigoni F, Yeo KK, Leow MK. Gender differences in fasting and postprandial metabolic traits predictive of subclinical atherosclerosis in an asymptomatic Chinese population. Sci Rep. 2022;12:16890. doi: 10.1038/s41598-022-20714-6
Khoo CY, Gao F, Choong HL, Tan WXA, Koniman R, Fam JM, Yeo KK. Death and cardiovascular outcomes in end-stage renal failure patients on different modalities of dialysis. Ann Acad Med Singap. 2022;51:136-142. doi: 10.47102/annals-acadmedsg.20219
Huang W, Ying TW, Chin WLC, Baskaran L, Marcus OEH, Yeo KK, Kiong NS. Application of ensemble machine learning algorithms on lifestyle factors and wearables for cardiovascular risk prediction. Sci Rep. 2022;12:1033. doi: 10.1038/s41598-021-04649-y
Huang B, Huang W, Allen JC, Sun L, Goh HJ, Kong SC, Lee D, Ding C, Bosco N, Egli L, Actis-Goretta L, Magkos F, Arigoni F, Leow MK, Tan SY, Yeo KK. Prediction of subclinical atherosclerosis in low Framingham risk score individuals by using the metabolic syndrome criteria and insulin sensitivity index. Front Nutr. 2022;9:979208. doi: 10.3389/fnut.2022.979208
Chan SH, Bylstra Y, Teo JX, Kuan JL, Bertin N, Gonzalez-Porta M, Hebrard M, Tirado-Magallanes R, Tan JHJ, Jeyakani J, Li Z, Chai JF, Chong YS, Davila S, Goh LL, Lee ES, Wong E, Wong TY, Consortium SGKH, Prabhakar S, Liu J, Cheng CY, Eisenhaber B, Karnani N, Leong KP, Sim X, Yeo KK, Chambers JC, Tai ES, Tan P, Jamuar SS, Ngeow J, Lim WK. Analysis of clinically relevant variants from ancestrally diverse Asian genomes. Nat Commun. 2022;13:6694. doi: 10.1038/s41467-022-34116-9
Ningyan Wong, Ignasius Aditya Jappar, Jien Sze Ho, See Hooi Ewe, Swee Yaw Tan, Jack Wei Chieh Tan, Kenny Yoong Kong Sin, Khung Keong Yeo. Torrential Tricuspid Regurgitation Treated with TricValve. Journal of Asian Pacific Society of Cardiology 2022;1:e05. DOI: https://doi.org/10.15420/japsc.2021.12
Cheney Jianlin Wong, Jonathan Yap, Fei Gao, Yee How Lau, Weiting Huang, Fazlur Jaufeerally, Ngiap Chuan Tan, Hee Hwa Ho, Mark Chan, Kelvin Bryan Tan, Khung Keong Yeo. Characteristics and Outcomes of MI with Non-obstructive Coronary Arteries in a South-east Asian Cohort. Journal of Asian Pacific Society of Cardiology 2022;1:e04. https://doi.org/10.15420/japsc.2021.04
Jack WC Tan, Jonathan Yap, Khung Keong Yeo, Derek P Chew, Alan Yean Yip Fong, Caitlyn Tan, Abdul Shehab, Quang Ngoc Nguyen, Terrence Chua, Clive Lawson, Danny Mathysen, Stephanie Thibault, Wael Almahmeed, Chris Plummer. European Examination in Core Cardiology (APSC Exit Examination). Journal of Asian Pacific Society of Cardiology 2022;1:e24. https://doi.org/10.15420/japsc.2022.15
Rilong Hong, Jonathan Yap, Khung Keong Yeo. Pericarditis and Myocarditis after mRNA based COVID-19 Vaccination. Journal of Asian Pacific Society of Cardiology 2022;1:e17. DOI: https://doi.org/10.15420/japsc.2021.26
Paul Jie Wen Tern, Yilin Jiang, Yee How Lau, Wael Almahmeed, S Gunavathy Selvaraj, Jack Wei Chieh Tan, Wan Azman Wan Ahmad, Jonathan Yap, Khung Keong Yeo. Impact of COVID-19 on Acute MI and Percutaneous Coronary Intervention Rates and Outcomes in South East Asia and the Middle East. Journal of Asian Pacific Society of Cardiology 2022;1:e05. DOI: https://doi.org/10.15420/japsc.2021.12
Wong Ningyan, Yeo Khung Keong. Percutaneous Edge-to-Edge Mitral Valve Repair for Functional Mitral Regurgitation. Int J Heart Fail.2022 Jan 13;4(2):55-74. doi: 10.36628/ijhf.2021.0041. eCollection 2022 Apr
Huang Weiting, Alwin Zhang Yaoxian, Yeo Khung Keong, Shao Wei Lam, Lau Yee How, Anders Olof Sahlén, Ahmadreza Pourghaderi, Matthew Che, Chua Siang Jin Terrance, Nicholas Graves. The clinical value and cost-effectiveness of treatments for patients with coronary artery disease. Health Econ Rev. 2022 Nov 8;12(1):56. doi: 10.1186/s13561-022-00401-y
Yeo KK, Tan JWC, Muller DW, Walters DL, Lindenfeld J, Lee MKY, Chui ASF, Satish S, Santoso T, Kubo S, Meng JCK, Sin KY, Ewe SH, Sim D, Tay E, Meemook K, Sung SH, Nguyen QN, Pan X, Amaki M, Izumo M, Hayashida K, Kim JS, Kang DY, Stone G, Matsumoto T. Asian Pacific Society of Cardiology Consensus Recommendations on the Use of MitraClip for Mitral Regurgitation. Eur Cardiol. 2021;16:e25. doi: 10.15420/ecr.2021.01
Yeo CYI, Allen JC, Jr., Huang W, Tan WY, Kong SC, Yeo KK. Improving the predictive capability of Framingham Risk Score for risk of myocardial infarction based on coronary artery calcium score in healthy Singaporeans. Singapore Med J. 2021. doi: 10.11622/smedj.2021151
Yap J, Anbalakan K, Tay WT, Ting D, Cheung CY, Sabanayagam C, Cheng CY, Wong TY, Yeo KK. Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population. BMJ Open Diabetes Res Care. 2021;9. doi: 10.1136/bmjdrc-2020-001413
Wong N, Tan WCJ, Widodo WA, Ong BC, Ding ZP, Ewe SH, Tang HC and Yeo KK. Dynamic mitral regurgitation treated with MitraClip. Ann Acad Med Singap. 2021;50:280-282.
Wong MYZ, Gunasekeran DV, Nusinovici S, Sabanayagam C, Yeo KK, Cheng CY and Tham YC. Telehealth Demand Trends During the COVID-19 Pandemic in the Top 50 Most Affected Countries: Infodemiological Evaluation. JMIR Public Health Surveill. 2021;7:e24445.
Wang ZS, Yap J, Koh YLE, Chia SY, Nivedita N, Ang TWA, Goh SCP, Lee CS, Tan LLJ, Ooi CW, Seow M, Yeo KK, Chua SJT and Tan NC. Predicting Coronary Artery Disease in Primary Care: Development and Validation of a Diagnostic Risk Score for Major Ethnic Groups in Southeast Asia. J Gen Intern Med. 2021;36:1514-1524.
Umapathy S, Keh YS, Wong N, Ho KW, Tan JWC, Wong ASL, Lim ST, Goh YS and Yeo KK. Real-World Experience of Coronary Intravascular Lithotripsy in an Asian Population: A Retrospective, Observational, Single-Center, All-Comers Registry. J Invasive Cardiol. 2021;33:E417-E424.
Tern PJW, Ho AKH, Sultana R, Ahn Y, Almahmeed W, Brieger D, Chew DP, Fong AYY, Hwang J, Kim Y, Komuro I, Maemura K, Mohd-Ali R, Quek DKL, Reid C, Tan JWC, Wan-Ahmad WA, Yasuda S and Yeo KK. Comparative overview of ST-elevation myocardial infarction epidemiology, demographics, management, and outcomes in five Asia-Pacific countries: a meta-analysis. Eur Heart J Qual Care Clin Outcomes. 2021;7:6-17.
Ozdemir S, Teo I, Bundoc FG, Malhotra C, Yeo KK, David Sim KL and Finkelstein EA. Role in decision making among congestive heart failure patients and its association with patient outcomes: a baseline analysis of the SCOPAH study. Patient Educ Couns. 2021;104:496-504.
Keh YS, Chin CY, Low AF and Yeo KK. OCT and IVUS Appearance of a Neointimal Dissection Within a Recently Implanted Left Main Stent. JACC Cardiovasc Interv. 2021;14:e31-e35.
Ding C, Egli L, Bosco N, Sun L, Goh HJ, Yeo KK, Yap JJL, Actis-Goretta L, Leow MK and Magkos F. Plasma Branched-Chain Amino Acids Are Associated With Greater Fasting and Postprandial Insulin Secretion in Non-diabetic Chinese Adults. Front Nutr. 2021;8:664939.
Chang X, Gurung RL, Wang L, Jin A, Li Z, Wang R, Beckman KB, Adams-Haduch J, Meah WY, Sim KS, Lim WK, Davila S, Tan P, Teo JX, Yeo KK, M Y, Liu S, Lim SC, Liu J, van Dam RM, Friedlander Y, Koh WP, Yuan JM, Khor CC, Heng CK and Dorajoo R. Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population. Commun Biol. 2021;4:519.
Campagne O, Yeo KK, Fangusaro J and Stewart CF. Clinical Pharmacokinetics and Pharmacodynamics of Selumetinib. Clin Pharmacokinet. 2021;60:283-303.
Bylstra Y, Lim WK, Kam S, Tham KW, Wu RR, Teo JX, Davila S, Kuan JL, Chan SH, Bertin N, Yang CX, Rozen S, Teh BT, Yeo KK, Cook SA, Jamuar SS, Ginsburg GS, Orlando LA and Tan P. Family history assessment significantly enhances delivery of precision medicine in the genomics era. Genome Med. 2021;13:3.
Yeo KK, Ong HY, Chua TSJ, Lim ZJ, Yap J, Ho HH, Jaufeerally F, Tong KL, Kojodjojo P, Wong HB, Heng D, Tan KB, Richards AM, Teoh KLK, Sin K, Tan NC, Lee SBM, Lim T, Ta A, Liok E, Lau YH, Gao F, Liman C, Sarkar J, Sahlén A, Koh TH, Chan MY. Building a Longitudinal National Integrated Cardiovascular Database ― Lessons Learnt From SingCLOUD. Circulation Reports 2020:33-43.
Yeo KK and Wong N. Percutaneous Edge-to-Edge Mitral Valve Repair. Korean Circ J. 2020;50:961-973.
Yeo KK, Azarbal F, Zakroysky P, Dai D, Roe M, Wojdyla D, Low R and Shunk K. Differential Longitudinal Outcomes Following Percutaneous Coronary Intervention to the Left Internal Mammary Artery and Other Bypass Grafts of the LAD: Findings From the NCDR. J Invasive Cardiol. 2020;32:E143-E150.
Wu RR, Sultana R, Bylstra Y, Jamuar S, Davila S, Lim WK, Ginsburg GS, Orlando LA, Yeo KK, Cook SA and Tan P. Evaluation of family health history collection methods impact on data and risk assessment outcomes. Prev Med Rep. 2020;18:101072.
Tai SB, Lau WR, Gao F, Hamid N, Amanullah MR, Fam JM, Yap J, Ewe SH, Chan MY, Yeo KK, Ding ZP and Sahlen A. E/e' in relation to outcomes in ST-elevation myocardial infarction. Echocardiography. 2020.
Sim HW, Zheng H, Richards AM, Chen RW, Sahlen A, Yeo KK, Tan JW, Chua T, Tan HC, Yeo TC, Ho HH, Liew BW, Foo LL, Lee CH, Hausenloy DJ and Chan MY. Beta-blockers and renin-angiotensin system inhibitors in acute myocardial infarction managed with inhospital coronary revascularization. Sci Rep. 2020;10:15184.
Paradies V, Zheng H, Chan MHH, Chan MYY, Foo DC, Lee CW, Lim ST, Tan HC, Tan JWC, Tong KL, Wong AS, Wong PE, Yeo KK, Foo LL, Chua TS, Koh TH, Bulluck H and Hausenloy DJ. Impact of time of onset of symptom of ST-segment elevation myocardial infarction on 1-year rehospitalization for heart failure and mortality. Am Heart J. 2020;224:1-9.
Li JJ, Liu HH, Wu NQ, Yeo KK, Tan K, Ako J, Krittayaphong R, Tan RS, Aylward PE, Baek SH, Dalal J, Fong AYY, Li YH, O'Brien RC, Lim TSE, Koh SYN, Scherer DJ, Tada H, Kang V, Butters J and Nicholls SJ. Statin intolerance: an updated, narrative review mainly focusing on muscle adverse effects. Expert Opin Drug Metab Toxicol. 2020;16:837-851.
Fam JM, Khoo CY, Lau YH, Lye WK, Cai XJ, Choong LHL, Allen JC and Yeo KK. Age and diabetes mellitus associated with worse outcomes after percutaneous coronary intervention in a multi-ethnic Asian dialysis patient population. Singapore Med J. 2020.
Cai JX, Yap J, Gao F, Koh TH, Tong KL, Ong HY, Kojodjojo P, Tan HC, Ong ME, Foo D, Ee B, Low LP, Chui P and Yeo KK. Elderly Asian Patients Have Lower Revascularisation Rates and Poorer Outcomes for ST-Elevation Myocardial Infarction Compared to Younger Patients. Ann Acad Med Singapore. 2020;49:3-14.
Jian-Jun Li, Hui-Hui Liu, Na-Qiong Wu, Khung Keong Yeo, Kathryn Tan, Junya Ako, Rungroj Krittayaphong, Ru San Tan, Philip E Aylward, Sang Hong Baek, Jamshed Dalal, Alan Yean Yip Fong, Yi-Heng Li, Richard C O’Brien, Tien Siang Eric Lim, Si Ya Natalie Koh, Daniel J Scherer, Hayato Tada, Vernon Kang, Julie Butters & Stephen J Nicholls (2020) Statin intolerance: an updated, narrative review mainly focusing on muscle adverse effects, Expert Opinion on Drug Metabolism & Toxicology, DOI: 10.1080/17425255.2020.1802426. 2020.
Zheng H, Foo LL, Tan HC, Richards AM, Chan SP, Lee CH, Low AFH, Hausenloy DJ, Tan JWC, Sahlen AO, Ho HH, Chai SC, Tong KL, Tan DSY, Yeo KK, Chua TSJ, Lam CSP and Chan MY. Sex Differences in 1-Year Rehospitalization for Heart Failure and Myocardial Infarction After Primary Percutaneous Coronary Intervention. Am J Cardiol. 2019;123:1935-1940.
Yeo KK, Wong N, Phua GC, Amanullah MR, Foo JS, Teo LL and Ewe SH. First Percutaneous Tricuspid Valve Repair with MitraClip Device in Singapore. Ann Acad Med Singapore. 2019;48:129-132.
Yap J, Ng Y, Yeo KK, Sahlen A, Lam CSP, Lee V and Ma S. Particulate air pollution on cardiovascular mortality in the tropics: impact on the elderly. Environ Health. 2019;18:34.
Wong N, Tan PCM, Ding ZP and Yeo KK. Successful MitraClip for severe rheumatic mitral regurgitation: a case report. Eur Heart J Case Rep. 2019;3:ytz155.
Teo JX, Davila S, Yang C, Hii AA, Pua CJ, Yap J, Tan SY, Sahlen A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK, Tan P and Lim WK. Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging. Commun Biol. 2019;2:361.
Tan JWC, Tan HJG, Sahlen AO, Yeo KK, Chin WLC, Gao F, Ong EHM, Yeo CP, Ng WY and Lim SH. Performance of cardiac troponins within the HEART score in predicting major adverse cardiac events at the emergency department. Am J Emerg Med. 2019:158420.
Sia CH, Dalakoti M, Tan BYQ, Lee ECY, Shen X, Wang K, Lee JS, Arulanandam S, Chow W, Yeo TJ, Yeo KK, Chua TSJ, Tan RS, Lam CSP and Chong DTT. A Population-wide study of electrocardiographic (ECG) norms and the effect of demographic and anthropometric factors on selected ECG characteristics in young, Southeast Asian males-results from the Singapore Armed Forces ECG (SAFE) study. Ann Noninvasive Electrocardiol. 2019;24:e12634.
Sahlen A, Ljungman P, Erlinge D, Chan MY, Yap J, Hausenloy DJ, Yeo KK and Jernberg T. Air pollution in relation to very short-term risk of ST-segment elevation myocardial infarction: Case-crossover analysis of SWEDEHEART. Int J Cardiol. 2019;275:26-30.
Cheung YB, Yeo KK, Chong KJ, Khoo EYH and Wee HL. Measurement equivalence of the English, Chinese and Malay versions of the World Health Organization quality of life (WHOQOL-BREF) questionnaires. Health Qual Life Outcomes. 2019;17:67.
Bylstra Y, Kuan JL, Lim WK, Bhalshankar JD, Teo JX, Davila S, Teh BT, Rozen S, Tan EC, Liew WKM, Yeo KK, Tan P, SinGapore Incidental Finding study g, Saw SM, Cheng CY, Cook S, Foo R and Jamuar SS. Population genomics in South East Asia captures unexpectedly high carrier frequency for treatable inherited disorders. Genet Med. 2019;21:207-212.
Bylstra Y, Davila S, Lim WK, Wu R, Teo JX, Kam S, Lysaght T, Rozen S, Teh BT, Yeo KK, Cook SA, Tan P and Jamuar SS. Implementation of genomics in medical practice to deliver precision medicine for an Asian population. NPJ Genom Med. 2019;4:12.
Bulluck H, Zheng H, Chan MY, Foin N, Foo DC, Lee CW, Lim ST, Sahlen A, Tan HC, Tan JW, Tong KL, Wong AS, Wong PE, Yeo KK, Foo LL, Chua TS, Koh TH and Hausenloy DJ. Independent Predictors of Cardiac Mortality and Hospitalization for Heart Failure in a Multi-Ethnic Asian ST-segment Elevation Myocardial Infarction Population Treated by Primary Percutaneous Coronary Intervention. Sci Rep. 2019;9:10072.
Bulluck H, Chowdhury N, Lim MX, Allen JC, Bryant JA, Chan MY, Chan MHH, Chin CWL, Ho HH, Lim ST, Tan RS, Tan JW, Wong PE, Yeo KK, Cook SA and Hausenloy DJ. Feasibility to Perform T2 * Mapping Postcontrast Administration in Reperfused STEMI Patients for the Detection of Intramyocardial Hemorrhage. J Magn Reson Imaging. 2019.
Zhang JM, Shuang D, Baskaran L, Wu W, Teo SK, Huang W, Gobeawan L, Allen JC, Tan RS, Su X, Ismail NB, Wan M, Su B, Zou H, Low R, Zhao X, Chi Y, Zhou J, Su Y, Lomarda AM, Chin CY, Fam JM, Keng FYJ, Wong ASL, Tan JWC, Yeo KK, Wong PEH, Chin CT, Ho KW, Yap J, Kassab GS, Chua T, Koh TH, Tan SY, Lim ST and Zhong L. Advanced analyses of computed tomography coronary angiography can help discriminate ischemic lesions. Int J Cardiol. 2018;267:208-214.
Yeo KK, Armstrong EJ, Lopez JE, Chen DC, Westin GG, Li CS, Anderson D, Hua A, Singapuri A, Amsterdam EA, Chiamvimonvat N and Laird JR. Aspirin and clopidogrel high on-treatment platelet reactivity and genetic predictors in peripheral arterial disease. Catheter Cardiovasc Interv. 2018;91:1308-1317.
Yap J, Singh GD, Kim JS, Soni K, Chua K, Neo A, Koh CH, Armstrong EJ, Waldo SW, Shunk KA, Low RI, Hong MK, Jang Y and Yeo KK. Outcomes of primary percutaneous coronary intervention in acute myocardial infarction due to unprotected left main thrombosis: The Asia-Pacific Left Main ST-Elevation Registry (ASTER). J Interv Cardiol. 2018;31:129-135.
Wong N, Hamid N, Tang HC and Yeo KK. Killing two birds with one stone-MitraClip for flail P2 and systolic anterior motion of mitral valve: a case report. Eur Heart J Case Rep. 2018;2:yty146.
Wee HL, Yeo KK, Chong KJ, Khoo EYH and Cheung YB. Mean Rank, Equipercentile, and Regression Mapping of World Health Organization Quality of Life Brief (WHOQOL-BREF) to EuroQoL 5 Dimensions 5 Levels (EQ-5D-5L) Utilities. Med Decis Making. 2018;38:319-333.
Seng MC, Shen X, Wang K, Chong DT, Fam JM, Hamid N, Amanullah MR, Yeo KK, Ewe SH, Chua TS, Ding ZP and Sahlen A. Allometric Relationships for Cardiac Size and Longitudinal Function in Healthy Chinese Adults- Normal Ranges and Clinical Correlates. Circ J. 2018;82:1836-1843.
Malhotra C, Foo R, Singh R, Ozdemir S, Teo I, Sim D, Jaufeerally F, Aung T, Keong YK, Nadkarni N and Finkelstein EA. Study protocol for a cohort study of patients with advanced heart failure in Singapore. BMJ Open. 2018;8:e022248.
Loh JP, Tan LL, Zheng H, Lau YH, Chan SP, Tan KB, Chua T, Tan HC, Foo D, Lee CW, Tong KL, Foo LL, Hausenloy D, Sahlen A, Yeo KK, Fox KAA, Wang TY, Richards AM and Chan MY. First Medical Contact-to-Device Time and Heart Failure Outcomes Among Patients Undergoing Primary Percutaneous Coronary Intervention. Circ Cardiovasc Qual Outcomes. 2018;11:e004699.
Lim WK, Davila S, Teo JX, Yang C, Pua CJ, Blocker C, Lim JQ, Ching J, Yap JJL, Tan SY, Sahlen A, Chin CW, Teh BT, Rozen SG, Cook SA, Yeo KK and Tan P. Beyond fitness tracking: The use of consumer-grade wearable data from normal volunteers in cardiovascular and lipidomics research. PLoS Biol. 2018;16:e2004285.
Lim FY, Yap J, Gao F, Teo LL, Lam CSP and Yeo KK. Correlation of the New York Heart Association classification and the cardiopulmonary exercise test: A systematic review. Int J Cardiol. 2018;263:88-93.
Lee PT, Loh J, Sng G, Tung J and Yeo KK. Empathy and burnout: a study on residents from a Singapore institution. Singapore Med J. 2018;59:50-54.
Huang W, Hammad K, Chao VTT and Yeo KK. Left Circumflex Artery Rupture with Left Atrial Tamponade and Functional Mitral Stenosis. Case Rep Cardiol. 2018;2018:8676572.
Cannistraci CV, Nieminen T, Nishi M, Khachigian LM, Viikila J, Laine M, Cianflone D, Maseri A, Yeo KK, Bhindi R and Ammirati E. "Summer Shift": A Potential Effect of Sunshine on the Time Onset of ST-Elevation Acute Myocardial Infarction. J Am Heart Assoc. 2018;7.
Balakrishnan ID, Chin CY, Teo L, Tan BY and Yeo KK. 'Balanced ischaemia' on ECG in dual territory STEMI. Oxf Med Case Reports. 2018;2018:omy043.
Aw TC, Huang WT, Le TT, Pua CJ, Ang B, Phua SK, Yeo KK, Cook SA and Chin CWL. High-Sensitivitycardiac Troponinsin Cardio-Healthy Subjects: A Cardiovascular Magnetic Resonance Imaging Study. Sci Rep. 2018;8:15409.
Yeo KK, Zheng H, Chow KY, Ahmad A, Chan BPL, Chang HM, Chong E, Chua TSJ, Foo DCG, Low LP, Ong MEH, Ong HY, Koh TH, Tan HC, Tang KF and Venketasubramanian N. Comparative analysis of recurrent events after presentation with an index myocardial infarction or ischaemic stroke. Eur Heart J Qual Care Clin Outcomes. 2017;3:234-242.
Tan XW, Zheng Q, Shi L, Gao F, Allen JC, Jr., Coenen A, Baumann S, Schoepf UJ, Kassab GS, Lim ST, Wong ASL, Tan JWC, Yeo KK, Chin CT, Ho KW, Tan SY, Chua TSJ, Chan ESY, Tan RS and Zhong L. Combined diagnostic performance of coronary computed tomography angiography and computed tomography derived fractional flow reserve for the evaluation of myocardial ischemia: A meta-analysis. Int J Cardiol. 2017;236:100-106.
Shen T, Teo TY, Yap JJ and Yeo KK. Gender Differences in Knowledge, Attitudes and Practices towards Cardiovascular Disease and its Treatment among Asian Patients. Ann Acad Med Singapore. 2017;46:20-28.
Cheung YB, Yeo KK, Chong KJ, Khoo EY and Wee HL. Reliability and Validity of the English-, Chinese- and Malay-Language Versions of the World Health Organization Quality of Life (WHOQOL-BREF) Questionnaire in Singapore. Ann Acad Med Singapore. 2017;46:461-469.
Ang LW, Yap J, Lee V, Chng WQ, Jaufeerally FR, Lam CSP, Cutter J, Yeo KK and Ma S. Influenza-Associated Hospitalizations for Cardiovascular Diseases in the Tropics. Am J Epidemiol. 2017;186:202-209.
Zhang JM, Zhong L, Luo T, Lomarda AM, Huo Y, Yap J, Lim ST, Tan RS, Wong AS, Tan JW, Yeo KK, Fam JM, Keng FY, Wan M, Su B, Zhao X, Allen JC, Kassab GS, Chua TS and Tan SY. Simplified Models of Non-Invasive Fractional Flow Reserve Based on CT Images. PLoS One. 2016;11:e0153070.
Yeo KK, Yap J, Tan JW, Lim ST and Koh TH. Venous Access Closure Using the Double-ProGlide Preclose Technique After MitraClip Implantation: Long-Term Clinical and Duplex Ultrasound Outcomes. J Invasive Cardiol. 2016;28:40-3.
Yap J, Earnest A, Lee V, Sng G, Lam C and Yeo KK. Impact of stock market volatility on mortality and cardiovascular events. Int J Cardiol. 2016;223:318-319.
Wong N, Chua SJT, Gao F, Sim STR, Matchar D, Wong SLA, Yeo KK, Tan WCJ and Chin CT. The effect of a nurse-led telephone-based care coordination program on the follow-up and control of cardiovascular risk factors in patients with coronary artery disease. Int J Qual Health Care. 2016;28:758-763.
Teo TY, Yap J, Shen T and Yeo KK. Complementary and alternative medicine use amongst patients with cardiovascular disease in Singapore. BMC Complement Altern Med. 2016;16:446.
Tay E, Muda N, Yap J, Muller DW, Santoso T, Walters DL, Liu X, Yamen E, Jansz P, Yip J, Zambahari R, Passage J, Ding ZP, Wang J, Scalia G, Soesanto AM and Yeo KK. The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation. Catheter Cardiovasc Interv. 2016;87:E275-81.
Tan ES, Yap J, Xu CF, Feng L, Nyunt SZ, Santhanakrishnan R, Chan MM, Seow SC, Ching CK, Yeo KK, Richards AM, Ng TP, Lim TW and Lam CS. Association of Age, Sex, Body Size and Ethnicity with Electrocardiographic Values in Community-based Older Asian Adults. Heart Lung Circ. 2016;25:705-11.
Sahlen A, Hamid N, Amanullah MR, Fam JM, Yeo KK, Lau YH, Lam CS and Ding ZP. Impact of aortic root size on left ventricular afterload and stroke volume. Eur J Appl Physiol. 2016;116:1355-65.
Keh YS, Yap J, Yeo KK, Koh TH and Eeckhout E. Clinical Outcomes of Bioresorbable Scaffold in Coronary Artery Disease: A Systematic Literature Review. J Interv Cardiol. 2016;29:57-69.
Gao F, Lam CS, Yeo KK, Machin D, de Carvalho LP, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Earnest A, Chua T and Chan MY. Influence of Ethnicity, Age, and Time on Sex Disparities in Long-Term Cause-Specific Mortality After Acute Myocardial Infarction. J Am Heart Assoc. 2016;5.
Devidutta S and Yeo KK. Acute stent thrombosis due to stent underexpansion managed with rotational atherectomy. Cardiovasc Revasc Med. 2016;17:66-70.68. Bulluck H, Foin N, Cabrera-Fuentes HA, Yeo KK, Wong AS, Fam JM, Wong PE, Tan JW, Low AF and Hausenloy DJ. Index of Microvascular Resistance and Microvascular Obstruction in Patients With Acute Myocardial Infarction. JACC Cardiovasc Interv. 2016;9:2172-2174.
Clinical Outcomes of Bioresorbable Scaffold in Coronary Artery Disease: A Systematic Literature Review. Keh YS, Yap J, Yeo KK, Koh TH, Eeckhout E. J Interv Cardiol. 2016 Jan 5. doi: 10.1111/joic.12260. [Epub ahead of print].
Correlation of the New York Heart Association Classification and the 6-Minute Walk Distance: A Systematic Review. Yap J, Lim FY, Gao F, Teo LL, Lam CS, Yeo KK. Clin Cardiol. 2015 Oct;38(10):621-8. doi: 10.1002/clc.22468. Epub 2015 Oct 7.
The MitraClip Asia-Pacific registry: Differences in outcomes between functional and degenerative mitral regurgitation. Tay E, Muda N, Yap J, Muller DW, Santoso T, Walters DL, Liu X, Yamen E, Jansz P, Yip J, Zambahari R, Passage J, Ding ZP, Wang J, Scalia G, Soesanto AM, Yeo KK. Catheter Cardiovasc Interv. 2015 Oct 28. doi: 10.1002/ccd.26289. [Epub ahead of print]
Venous Access Closure Using the Double-ProGlide Preclose Technique After MitraClip Implantation: Long-Term Clinical and Duplex Ultrasound Outcomes. Yeo KK, Yap J, Tan JW, Lim ST, Koh TH. J Invasive Cardiol. 2015 Nov 15. pii: JIC20151115-3. [Epub ahead of print]
Acute stent thrombosis due to stent underexpansion managed with rotational atherectomy. Devidutta S, Yeo KK. Cardiovasc Revasc Med. 2015 Nov 11. pii: S1553-8389(15)00266-3. doi: 10.1016/j.carrev.2015.10.003. [Epub ahead of print]
Percutaneous mitral valve repair with the mitraclip: Early results from the mitraclip asia-pacific registry (mars). Yeo KK, Yap J, Yamen E, Muda N, Tay E, Walters DL, Santoso T, Liu X, Jansz P, Yip J, Zambahari R, Passage J, Koh TH, Wang J, Scalia G, Kuntjoro I, Soesanto AM, Muller D. EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 2014
Association between statin medications and mortality, major adverse cardiovascular event, and amputation-free survival in patients with critical limb ischemia. Westin GG, Armstrong EJ, Bang H, Yeo KK, Anderson D, Dawson DL, Pevec WC, Amsterdam EA, Laird JR. Journal of the American College of Cardiology. 2014;63:682-690
Endovascular recanalization of infrapopliteal occlusions in patients with critical limb ischemia. Singh GD, Armstrong EJ, Yeo KK, Singh S, Westin GG, Pevec WC, Dawson DL, Laird JR. Journal of vascular surgery. 2014
Angiographic characteristics of definite stent thrombosis: Role of thrombus grade, collaterals, epicardial coronary flow, and myocardial perfusion. Reeves RR, Patel M, Armstrong EJ, Sab S, Waldo SW, Yeo KK, Shunk KA, Low RI, Rogers JH, Mahmud E. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. 2014
Nitinol self-expanding stents vs. Balloon angioplasty for very long femoropopliteal lesions. Armstrong EJ, Saeed H, Alvandi B, Singh S, Singh GD, Yeo KK, Anderson D, Westin GG, Dawson DL, Pevec WC, Laird JR. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists. 2014;21:34-43
Adherence to guideline-recommended therapy is associated with decreased major adverse cardiovascular events and major adverse limb events among patients with peripheral arterial disease. Armstrong EJ, Chen DC, Westin GG, Singh S, McCoach CE, Bang H, Yeo KK, Anderson D, Amsterdam EA, Laird JR. Journal of the American Heart Association. 2014;3:e000697
Association between statin medications and mortality, major adverse cardiovascular event, and amputation-free survival rates in patients with critical limb ischemia. Westin GG, Armstrong EJ, Bang H, Yeo KK, Anderson D, Dawson DL, Pevec WC, Amsterdam EA, Laird JR. J Am Coll Cardiol. 2013
Mid-term outcomes following endovascular re-intervention for iliac artery in-stent restenosis Catheter Cardiovasc Interv. Javed U, Balwanz CR, Armstrong EJ, Yeo KK, Singh GD, Singh S, Anderson D, Westin GG, Pevec WC, Laird JR. 2013 Apr 24
Transradial and transfemoral coronary angiography and interventions: 1-Year outcomes after initiating the transradial approach in a cardiology training program. Balwanz CR, Javed U, Singh GD, Armstrong EJ, Southard JA, Wong GB, Yeo KK, Low RI, Laird JR Jr, Rogers JH. American heart journal. Mar 2013;165(3):310-316.
Comparison of procedural success and long-term outcomes of stent thrombosis in coronary bypass grafts versus native coronary arteries. Waldo SW, Armstrong EJ, Yeo KK, et al. The American journal of cardiology. Mar 1 2013;111(5):689-694.
Gender-related variation in the clinical presentation and outcomes of critical limb ischemia. McCoach CE, Armstrong EJ, Singh S, Javed U, Anderson D, Yeo KK, Westin GG, Hedayati N, Amsterdam EA, Laird JR Jr. Vascular medicine. Feb 2013;18(1):19-26.
Percutaneous mitral valve repair with MitraClip for severe functional mitral regurgitation. Yeo KK, Ding ZP, Chua YL, et al. Singapore medical journal. Jan 2013;54(1):e9-e12.
Procedural success and long-term outcomes of aspiration thrombectomy for the treatment of stent thrombosis. Waldo SW, Armstrong EJ, Yeo KK, Patel M, Reeves R, Macgregor JS, Low RI, Mahmud E, Rogers JH, Shunk K. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2013
Angiographic characteristics of femoropopliteal in-stent restenosis: Association with long-term outcomes after endovascular intervention. Armstrong EJ, Singh S, Singh GD, Yeo KK, Ludder S, Westin G, Anderson D, Dawson DL, Pevec WC, Laird JR. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. 2013
Excimer laser with adjunctive balloon angioplasty and heparin-coated self-expanding stent grafts for the treatment of femoropopliteal artery in-stent restenosis: twelve-month results from the SALVAGE study. Laird JR, Jr., Yeo KK, Rocha-Singh K, et al. Catheter Cardiovasc Interv. Nov 1 2012;80(5):852-859.
Right pace, wrong place. Ann Acad Med Singapore. Lim CP, Yeo KK, Tan BY, Liew R, Tan JW. Sep 2012;41(9):417-419.
Coronary artery bypass operations for elderly patients in California, 2003 to 2008. Li Z, Amsterdam EA, Yeo KK, et al. Ann Thorac Surg. Apr 2012;93(4):1167-1172.
Angiographically confirmed stent thrombosis in contemporary practice: Insights from intravascular ultrasound. Armstrong EJ, Kwa AT, Yeo KK, et al. Catheter Cardiovasc Interv. Apr 18 2012.
Contemporary clinical characteristics, treatment, and outcomes of angiographically confirmed coronary stent thrombosis: results from a multicenter California registry. Yeo KK, Mahmud E, Armstrong EJ, et al. Catheter Cardiovasc Interv. Mar 1 2012;79(4):550-556.
Comparison of clinical characteristics, treatments and outcomes of patients with ST-elevation acute myocardial infarction with versus without new or presumed new left bundle branch block (from NCDR(R)). Yeo KK, Li S, Amsterdam EA, et al. The American journal of cardiology. Feb 15 2012;109(4):497-501.
AsiaPCR/SingLive: in its third year and growing. Lim E, Lim CP, Muller O, Yeo KK, Lim ST, Koh TH, Eechkout E. EuroIntervention. Feb 2012;7(10):1144-1146.
Clinical presentation, management, and outcomes of angiographically documented early, late, and very late stent thrombosis. Armstrong EJ, Feldman DN, Wang TY, Kaltenbach LA, Yeo KK, Wong SC, Spertus J, Shaw RE, Minutello RM, Moussa I, Ho KK, Rogers JH, Shunk KA. JACC Cardiovasc Interv. Feb 2012;5(2):131-140.
The treatment of femoropopliteal in-stent restenosis: back to the future. Laird JR, Yeo KK. J Am Coll Cardiol. Jan 3 2012;59(1):24-25.
Angiographic stent thrombosis at coronary bifurcations: short- and long-term prognosis. Armstrong EJ, Yeo KK, Javed U, et al. JACC Cardiovasc Interv. Jan 2012;5(1):57-63.
Outcomes following treatment of femoropopliteal in-stent restenosis: A single center experience. Yeo KK, Malik U, Laird JR. Catheterization and cardiovascular interventions: official journal of the Society for Cardiac Angiography & Interventions. May 12 2011.
Early duplex scanning after infrainguinal endovascular therapy. Humphries MD, Pevec WC, Laird JR, Yeo KK, Hedayati N, Dawson DL. J Vasc Surg. Feb 2011;53(2):353-358.
Relation of race, ethnicity and cardiac surgeons to operative mortality rates in primary coronary artery bypass grafting in California. Castellanos LR, Li Z, Yeo KK, Young JN, Ayanian JZ, Amsterdam EA. The American journal of cardiology. Jan 2011;107(1):1-5.
Life-threatening coronary sinus thrombosis following catheter ablation: case report and review of literature. Yeo KK, Davenport J, Raff G, Laird JR. Cardiovasc Revasc Med. Oct-Dec 2010;11(4):262 e261-265.
Early duplex scanning after infrainguinal endovascular therapy. Humphries MD, Pevec WC, Laird JR, Yeo KK, Hedayati N, Dawson DL. J Vasc Surg. Oct 23 2010.
Off-pump bypass surgery and postoperative stroke: California coronary bypass outcomes reporting program. Li Z, Denton T, Yeo KK, et al. Ann Thorac Surg. Sep 2010;90(3):753-759.
The role of stent-grafts for prevention and treatment of restenosis. Kwa AT, Yeo KK, Laird JR. J Cardiovasc Surg (Torino). Aug 2010;51(4):579-589.
Operative mortality in women and men undergoing coronary artery bypass grafting (from the California Coronary Artery Bypass Grafting Outcomes Reporting Program). Bukkapatnam RN, Yeo KK, Li Z, Amsterdam EA. The American journal of cardiology. Feb 1 2010;105(3):339-342.
Recovery of methamphetamine associated cardiomyopathy predicted by late gadolinium enhanced cardiovascular magnetic resonance. Lopez JE, Yeo KK, Caputo G, Buonocore M, Schaefer S. J Cardiovasc Magn Reson. 2009;11:46.
Late surgical mitral valve repair after percutaneous repair with the MitraClip system. Rogers JH, Yeo KK, Carroll JD, et al. J Card Surg. Nov-Dec 2009;24(6):677-681.
The effect of posture on Cheyne-Stokes respirations and hemodynamics in patients with heart failure. Soll BA, Yeo KK, Davis JW, Seto TB, Schatz IJ, Shen EN. Sleep. Nov 2009;32(11):1499-1506.
A comparison of echocardiographic findings in young adults with cardiomyopathy: with and without a history of methamphetamine abuse. Ito H, Yeo KK, Wijetunga M, Seto TB, Tay K, Schatz IJ. Clin Cardiol. Jun 2009;32(6):E18-22.
Off-pump coronary artery bypass graft surgery in California, 2003 to 2005. Li Z, Yeo KK, Parker JP, Mahendra G, Young JN, Amsterdam EA. American heart journal. Dec 2008;156(6):1095-1102
Percutaneous treatment of a large superior mesenteric artery pseudoaneurysm and arteriovenous fistula: a case report. Yeo KK, Dawson DL, Brooks JL, Laird JR. J Vasc Surg. Sep 2008;48(3):730-734.
Direct flow medical percutaneous aortic valve: proof of concept. Low RI, Bolling SF, Yeo KK, Ebner A. EuroIntervention. Aug 2008;4(2):256-261.
Food and Drug Administration-approved endovascular repair devices for abdominal aortic aneurysms: a review. Tan JW, Yeo KK, Laird JR. J Vasc Interv Radiol. Jun 2008;19(6 Suppl):S9-S17.
Excimer laser assisted angioplasty for complex infrainguinal peripheral artery disease: a 2008 update. Tan JW, Yeo KK, Laird JR. J Cardiovasc Surg (Torino). Jun 2008;49(3):329-340.
Severity of chronic kidney disease as a risk factor for operative mortality in nonemergent patients in the California coronary artery bypass graft surgery outcomes reporting program. Yeo KK, Li Z, Yeun JY, Amsterdam E. The American journal of cardiology. May 1 2008;101(9):1269-1274.
Use of stent grafts and coils in vessel rupture and perforation. Yeo KK, Rogers JH, Laird JR. J Interv Cardiol. Feb 2008;21(1):86-99.
Aortic stenosis: assessment of the patient at risk. Yeo KK, Low RI. J Interv Cardiol. Dec 2007;20(6):509-516.
Dual mechanism platypnea-orthodeoxia syndrome from severe right coronary artery stenosis and a patent foramen ovale. Yeo KK, Rogers JH. Catheter Cardiovasc Interv. Sep 2007;70(3):440-444.
Clinical characteristics and 30-day mortality among Caucasians, Hispanics, Asians, And African-Americans in the 2003 California coronary artery bypass graft surgery outcomes reporting program. Yeo KK, Li Z, Amsterdam E. The American journal of cardiology. Jul 1 2007;100(1):59-63.
The association of methamphetamine use and cardiomyopathy in young patients. Yeo KK, Wijetunga M, Ito H, et al. Am J Med. Feb 2007;120(2):165-171.
Ethnicity modifies the association between diabetes mellitus and ischaemic heart disease in Chinese, Malays and Asian Indians living in Singapore. Yeo KK, Tai BC, Heng D, et al. Diabetologia. Dec 2006;49(12):2866-2873.
Valve replacement in endocarditis: setting limits in noncompliant intravenous drug abusers. Yeo KK, Chang WJ, Lau JM, Tan SY. Hawaii Med J. Jun 2006;65(6):168, 170-161.
Tachycardia-induced elevations in cardiac troponin in the absence of coronary artery disease. Yeo KK, Cruz L, Hong R. Hawaii Med J. Mar 2006;65(3):86-87.
Procedural success and complications following percutaneous coronary interventions among Asians and Pacific Islanders. Yeo KK, Beauvallet S, Mau MK, Seto TB. Clin Cardiol. Sep 2005;28(9):429-432.
Multiple cardiac papillary fibroelastoma and transient left ventricular apical ballooning syndrome in an elderly woman: case report. Yeo KK, Fukuyama O. J Heart Valve Dis. Jan 2005;14(1):137-139.
Stereotactic brain biopsies in AIDS patients--early local experience. Yeo KK, Yeo TT, Chan CY, Sitoh YY, Teo J, Wong SY. Singapore medical journal. Apr 2000;41(4):161-166.

Research Trials

The role of aspirin and thienopyrdine non-responsiveness in peripheral arterial disease, PI
3-Dimensional Reconstruction and Quantitation of the Mitral Valve by Echocardiography for Assessment of Short and Long Term Consequences of Percutaneous Repair of Mitral Regurgitation, PI
Long-term clinical outcomes, cost-of-care, quality-of-care and re-admission rates in patients with coronary artery disease or congestive heart failure in Singapore (SingCLOUD): Proof of Concept, PI
Empathy in SingHealth Residents, PI, 31 Mar 2015 – 31 Mar 2017 (2 years)
A portable video-based patient education tool for cardiac catheterisation, PI, 1 Oct 2015 – 30 Sep 2017 (2 years)
SingHEART: A long-term longitudinal study on the cardiovascular health of normal people with biobanking, deep phenotyping, cardiac MRI and physical activity, PI, 1 Jun 2015 – 1 Jun 2016 (1 year)
Genomics in Cardiovascular Medicine: Proof of Concept Pilot, PI, 2016 – 2017 (1 year)
Implementation of ICHOM in NHCS: Pilot, PI, 2017 – 2018 (1 year)
ARROW : identificAtion of postpRandial biomaRkers tOWards cardiovascular prevention, PI, 2017 – 2019 (2 years)
Trisail: A Percutaneous Tricuspid Valve Repair/Replacement Device, PI, 2018 – 2022 (4 years)
Long-term clinical outcomes, cost-of-care, clinical characteristics, re-admission rates, outpatient care and mortality in patients with coronary artery disease, congestive heart failure or atrial fibrillation in Singapore ("SingCLOUD" for Singapore Cardiac Longitudinal OUtcomes Database Study), PI, 2019 – 2022 (3 years)
A Percutaneous Tricuspid Valve Repair/Replacement Device, PI, 2020 – 2021 (1 year)
SingHEART, PI, 2020 – 2022 (2 years)
TRISAIL: A Percutaneous Tricuspid Valve Repair/Replacement Device, PI, 2020 – 2022 (2 years)
MYOVAx (Pathophysiologic Mechanism for MYOcarditis in COVID19 Vaccinations) (COVID19RF-0016), PI, 2021 – 2023 (2 years)
An updated wearable magnetic flux device to optimize blood pressure control, PI, 2021 – 2023 (2 years)
JARVISDHL: Transforming Chronic Care for Diabetes, Hypertension and hyperLipidemia with AI, PI, 2021 – 2023 (2 years)
Active Delivery of Sirolimus-loaded ultrasound-responsive Multi-cavity microparticle (SSMPs) for the treatment of vascular restenosis, PI, 2022 – 2023 (1 year)
CArdiovascular DiseasE National Collaborative Enterprise (CADENCE), PI, 2023 – 2026 (3 years)
SingHEART: A long-term longitudinal study on the cardiovascular health of normal people with biobanking, deep phenotyping, cardiac MRI and physical activity, PI, 2024 – 2029 (5 years)