The signs and symptoms of gallbladder cancer are not always apparent in its early stages. When symptoms do appear, they may include:

• Abdominal pain, particularly in the upper right side, which may be persistent or intermittent.
• Unexplained weight loss
• Jaundice, or yellowing of the skin and eyes, caused by bile duct obstruction.
• Nausea and vomiting, especially if the cancer has progressed and is affecting digestion.
• Loss of appetite, which may contribute to weight loss and general weakness.
• Bloating or a sense of fullness in the abdomen, even after eating small amounts.
• Fever, which may indicate infection or inflammation associated with gallbladder cancer.